Danio rerio is one of the best model organisms to study various kinds of disorders. Their genome is fully sequenced and they possess easily detectable developmental properties. The development of their embryo is quite rapid. This is important as the embryos are formed by external fertilization, are large and transparent. Abortifacient is a substance that induces abortion. It can be used in the for...
Endodontic treatment is helpful in saving millions of teeth each year, but at present the focus has shifted towards regenerative approaches as an ideal form of therapy to treat diseased or necrotic pulp tissues. Regeneration of lost tissues has been known for a very long time, but their use in dentistry is gaining momentum. The growing understanding of biological regeneration has permitted the use...
MORPHOMETRY OF THE THYROID GLAND IN DIFFERENT AGE GROUPS IN NORTH INDIAN POPULATION: A CADAVERIC STUDY
Aims and Objectives: The present study was conducted to find out morphometry of thyroid gland in different age groups. Material and Methods: The study was conducted on 60 human thyroid glands in the Department of Anatomy, Pt. B. D. Sharma, PGIMS, Rohtak in North Indian population. Results: In present study, mean length of right and left lobe of thyroid gland was found to be 29.88±7.03 mm and 29.4...
The requirement of drug resistance regularly to plague Tuberculosis control, with vast increase in the spreading of MDR-TB. It can act as a gateway to XDR-TB and then emphasis on the urgency for new drug development and optimal treatment option for Tuberculosis therapy. In this study, we assess the recommending for using Rifabutin (RFB) instead of rifampicin (RIF). The objective of this study and ...
ANTIHYPERTENSIVE EFFECT OF THE ALCOHOLIC EXTRACT OF SEEDS OF PHASEOLUS VULGARIS LINN. (FABACEAE) ON HIGH SALT DIET INDUCED HYPERTENSION IN MALE RATS
Aim: To evaluate the antihypertensive effect of ethanolic extract of seeds of Phaseolus vulgaris Linn. (EEPV) on high salt diet induced hypertension in male rats. Methods: Male wistar rats (180-200g) received high salt diet (8% NaCl) and 1% saline water for 6 weeks, then cannulated for dosing of Enalapril, angiotensin converting enzyme inhibitor (0.5 mg/kg, i.v.) in standard group and EEPV (50 and...
STORAGE OF WORKING STANDARDS IN POLYPROPYLENE CONTAINERS, ITS EFFECT, CONTAMINANTS AND IMPACT ON ANALYSIS ON LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROSCOPY
Authorspropose a method to determine the contamination caused during the storage of colchicine stock solution, which will be helpful for the bioanalytical scientists. The process of identification of impurities, exceptionally in this case, started from the point of optimization of the compound, where in the parent ion was not detected and instead an unknown mass is being interpreted by the detecto...
PHYTOCHEMICAL SCREENING AND IN-VITRO STUDIES OF ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF EXTRACTS OF DRIED STEVIA REBAUDIANA LEAVES
The present study is based on the comparative evaluation of preliminary phytochemical screening and in vitro antimicrobial activity of methanolic and ethanolic extracts of Stevia rebaudiana leaves. The crude extracts of S. rebaudiana leaves were subjected to phytochemical screening tests by using standard procedures for the detection of the presence or absence of eight major secondary metabolites....
SELF-REPORTED CHRONIC ILLNESSES AND USE OF PRESCRIPTION MEDICINES (PM) AMONG ELDERLY MALAYS- A COMMUNITY BASED STUDY
This study explored self-reported chronic illnesses and use of prescription medicines (PM) by elderly Malays in the community. The study was a population based cross sectional study conducted among 490 Malay subjects aged ≥ 60 years in the semi-urban and rural areas in Perak, Malaysia. The study was conducted using pre-validated questionnaires after getting informed consent from the study partic...
Aim and Objective: To evaluate the antioxidant property of fish oil by its free radical scavenging activity using three different antioxidant models. Materials and Methods: In vitro antioxidant activity of fish oil was evaluated by DPPH radical scavenging activity, lipid peroxidation, ABTS radical scavenging activity using olive oil as positive control. Different concentrations of the fish oil, 0....
EVALUATION OF HEPATOPROTECTIVE AND ANTI-OXIDANT ACTIVITY OF ROOT EXTRACTS OF AEGLE MARMELOS IN CARBON TETRACHLORIDE INDUCED HEPATOTOXICITY WISTAR ALBINO RATS
Herbal medicines are effective in the treatment of various ailments. Very often these drugs are unscientifically exploited and / or improperly used. Therefore plant drugs deserve detailed studies in the light of modern science. The detailed investigation and documentation of plants used in local health traditions and pharmacological evaluation of these plants and their taxonomical relatives can le...