Black pepper, the ‘King of spices’ (Piper nigrum L.), is a widely used spice, known for its pungent odour. From time immemorial, plant sources were used in traditional systems of medicine and day-to-day common use, such as in meal preparation and cosmetic purposes. This is due to their vast pharmacological potential with minimum side effects. Among the various species of the Piperaceae family,...
Dalbergia spinosa Roxb. (Leguminosae) is a mangrove plant native to Asia and enjoys number of traditional uses. This paper describes the investigation of antibacterial and cytotoxic activity of the ethanol extract of D. spinosa leaves. Antibacterial activity of the ethanol extract of D. spinosa leaves was tested by disc diffusion assay and broth macrodilution assay. The extract was also tested for...
Pyrimidine is a 5-membered heterocyclic ring which is versatile lead compound for designing potent bioactive agents. This interesting group of compound has diverse biological activities such as antimicrobial, CNS depressant, anti-inflammatory, analgesic, anti-convulsant, anticancer, antihelmentic, antioxidant and herbicidal. Available data represents that pyrimidine being heterocyclic planar five ...
DEVELOPMENT AND VALIDATION OF A HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR DETERMINATION OF CEFIXIME TRIHYDRATE AND ITS DEGRADED PRODUCTS FORMED UNDER STRESS CONDITION OF UV LIGHT
A simple, accurate, precise and sensitive reverse phase high performance liquid chromatography (RP-HPLC) method for the determination of cefixime trihydrate and its degraded products have been developed and validated. Drug was resolved on a C18 column (waters spherisorb 25 cm × 4.6 mm, 5µm), utilizing mobile phase of sodium dihydrogen phosphate monohydrate (0.1M aqueous) pH adjusted to 2.5 with ...
A survey of green synthesis of thiazines and oxazines revealed the moiety have attracted a great deal of interest of medicinal chemist, biochemist, pharmacologist and rendered as a lead molecule for designing potential bioactive agents. This review accompanying supplementary green synthetic information & its references would extend great deal of help to researchers in determining the best and ...
EFFICACY AND MECHANISMS OF MEDICINAL PLANTS AS IMMUNOTHERAPY IN TREATMENT OF ALLERGIC RHINITIS: A SYSTEMATIC REVIEW
Allergic rhinitis is a common disease of immune system that negatively affects general health, quality of life, and social relationships. In the recent years, many studies have been conducted to discover novel treatments for this disease particularly using natural products. Here, we review findings of recent studies that harness medicinal plants and phyto-therapies in oriental medicine that have e...
COST VARIATION ANALYSIS OF ANTIHYPERTENSIVE DRUGS AVAILABLE IN INDIAN MARKET: AN ECONOMIC PERSPECTIVE
Aim: To analyze the percentage cost variations among different brands of the commonly prescribed anti–hypertensive drugs. Materials and Methods: The cost of different brands of commonly used antihypertensive drugs was sorted out by referring latest CIMS, MIMS, Drugs Monitor and IDR. The cost of 10 dosage forms (Tablets / capsules) in INR of each brand, Cost Ratio and Percentage Cost Variation we...
Cotoneaster is a plant from Rosaceae family and produces a sugary secretion (manna). Manna is the most important constituent of species of this plant. Manna consists of different types of carbohydrates, and other phytochemicals. Sugar characterization, including reducing sugar was assayed by cupric/sodium carbonate spectrophotometric method. In addition, the composition of individual sugars was al...
PRODUCTION OF REACTIVE OXYGEN SPECIES, ITS EFFECT, DRUGS AND PLANT EXTRACT USED AS AN ANTIOXIDANT, CHELATOR ON THALASSEMIC PATIENT: A REVIEW
β- Thalassemia is an inherited genetic disorder which is caused by different kinds of mutations in the HBB gene in chromosome 11. Due to several types of mutation in β- gene, globin chains cannot synthesise completely and free α-globin is highly unstable and readily precipitates bound heme and iron. In β- thalassemia these precipitated iron, repeated blood transfusion and increased gastroint...
Background: Gouania longipetala Hemsl. (Rhamnaceae), has ethnomedicinal use in the treatment of wounds, gonorrhoea, abdominal pain, lumbago, ophthalmia, conjunctivitis, and rickets. However, no scientific investigation of these effects has been established. Our aim was to verify the antibacterial, antioxidant and anti-inflammatory effects of the stem of Gouania longipetala. Methods: The antibact...