Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
EFFECT OF CURCUMIN SUPPLEMENTATION ON THE SUBMANDIBULAR SALIVARY GLANDS OF D-GALACTOSE INDUCED MALE MICE
Significant increase in the salivary gland lipid peroxidation, fluorescence product as well as accumulation of lipofuscin granules–age pigment was observed after injection of 5% D-galactose 0.5 ml daily for 30 days. Supplementations of turmeric extract (30mg/kg body weight) for 30 days during and after D-galactose treatment significantly reduced all the above parameters. Histochemical changes in...
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PHYTOCHEMICAL STUDIES ON CASUARINA EQUISETIFOLIA AND INVESTIGATION OF ITS EFFECT AGAINST PATHOGENIC ORAL FLORA
This research was targeted to reveal the phytochemical activity of Casuarina equisetifolia against susceptible pathogenic oral bacteria. Antibacterial effect of the plant was examined by well diffusion method. Different plant parts were screened for the phytochemicals using various polar solvents like ethanol, acetone, methanol, chloroform and water. Studies disclosed that Casuarina equisetifolia ...
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FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLET
The objective of the present study was to develop venlafaxine hydrochloride orodispersible tablet by using conventional techniques which are simple and cost effective such as use of superdisintegrant technology. In this, sodium starch glycolate and Crosscarmellose sodium crosspovidone and kyron-T-314 were used in the rapid disintegration of the tablets. In this various trials were conducted for th...
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OXIDATION OF TRICYCLIC ANTIDEPRESSANT AGENT, AMITRIPTYLINE, BY PERMANGANATE IN SULPHURIC ACID MEDIUM: KINETIC AND MECHANISTIC APPROACH
The kinetics of oxidation of amitriptyline by potassium permanganate in aqueous sulphuric acid medium at 298K and at a constant ionic strength of 0.20 mol dm-3 has been investigated spectrophotometrically. The reaction exhibits 5:4 stoichiometry (5 Amitriptyline:4 KMnO4). The reaction was first order with respect to manganese(VII) concentration. The order with respect to amitriptyline was found to...
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ANTIBIOTIC SUSCEPTIBILITY PATTERN OF STAPHYLOCOCCUS AUREUS STRAINS FROM PATIENTS IN ETHIOPIA
Staphylococcus aureus (S. aureus) is one of the most serious gram-positive bacteria causing several infections. Because of its intrinsic ability to develop resistance to many antibiotics, nowadays only few drugs can be confidently mentioned for the treatment of S. aureus infections. The study aimed to investigate the antibiotics susceptibility pattern of S. aureus among patients. A cross-sectio...
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PREPARATION AND EVALUATION OF CYCLODEXTRIN COMPLEXATION OF ETORICOXIB
Cyclodextrin complexes of etoricoxib (poorly water soluble COX-2 inhibitor) were prepared with the β-CD and HPβ-CD by different techniques (physical mixture, kneading and co-evaporation methods) at 1:1 and 1:2 molar ratios. Characterization of the complexes was done in solution by phase solubility analysis and in solid state using FTIR. The stoichiometry and stability constants of ECB-β-CD (1:1...
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IDENTIFICATION OF SIGNIFICANT PATHWAYS RESPONSIBLE FOR AUTISM THROUGH MOLECULAR NETWORK ANALYSIS
Autism is a spectrum of developmental disorders characterized by impairments in social interaction, communication, often accompanied by stereotypical or repetitive behaviours. There are numerous hypotheses holding to the etiology and pathology of Autism but actual mechanism of the ailment is still unknown. Although a number of rare mutations and dosage abnormalities are specific to autism, these e...
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ANALYTICAL METHOD DEVELOPMENT OF ESOMEPRAZOLE IN BULK AND SINGLE COMPONENT FORMULATION
Esomeprazole is a proton pump inhibitor which reduces gastric acid secretion through inhibition of H+/K+-ATPase in gastric parietal cells. By inhibiting the functioning of this enzyme, the drug prevents formation of gastric acid. Esomeprazole is combined with the antibiotics, clarithromycin and amoxicillin (or metronidazole in penicillin-hypersensitive patients) in the 7-14 day eradication triple ...
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PLGA: A POLYMER OF CHOICE AS NANOCARRIER’S TO ACHIEVE EFFECTIVE DELIVERY OF MEDICINAL SUBSTANCES
Poly (D,L-lactide-co-glycolic acid) the first synthetic biodegradable polymer used in surgery as resorbabe material, is also approved by USFDA for use in drug delivery. The nanoparticle composed of PLGA can be used for both controlled and targeted drug delivery. There are various grades of PLGA which are having different biodegradation characteristics such as degradation takes place in several day...
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STATUS OF TUBERCULOSIS IN KANPUR CITY AND ROLE OF PHARMACIST AS A HEALTHCARE PROFESSIONAL IN TREATMENT AND CONTROL OF TUBERCULOSIS
Tuberculosis (TB) is a growing international health concern and it is estimated that a third of the world's population is currently infected with TB. The increasing prevalence of multidrug-resistant (MDR)-TB has greatly increased difficulties in its treatment and control. Therefore, the present study was perceived to check the status of tuberculosis at Kanpur, one of the largest city of Uttar Prad...
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