Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
BIOLOGICAL EVALUATIONS OF POTENTIAL HERB- NERIUM INDICUM (LINN.)
The methanolic extract of Nerium indicum showed the presence of alkaloids, tannins, phenols, and starch in phyto-chemical investigation. Total phenolic content of the drug was estimated by Folin Ciocatteu’s method and was found to be 55.20 µg/10 ml. Analgesic activity was performed using three models they are Writhing, Tail-flick activity and Hot plate models. The methanoilc extract showed 44...
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EFFICACY OF EMBLICA OFFICINALIS FRUITS IN LPO AND ANTIOXIDANTS ON LEAD TREATED RATS
Emblica officinalis (EO) a native plant of India is used in a variety of conditions and to treat a host of ailments besides being a rich source of Vitamin C. The efficacy of this fruit powder administered orally in lead induced toxicity was investigated in rats. Lipid peroxidation and antioxidant enzymes of lead induced and treated rats were studied in liver and kidney. The changes observed in tox...
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¬POST-STROKE DEPRESSION: PATHOLOGLOGY, DIAGNOSIS AND TREATMENT STRATEGY
Post stroke depression is most commonly faced psychiatric challenge, causing severe disability. Post stroke depression (PSD) occurs in nearly one-third patients either during acute/chronic stroke period. It’s often under-diagnosed. A good diagnosis must be done within one month after stroke, based on self-reporting tools, followed by observer-rated interview. Mechanism is multifactorial, present...
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DOUBLE LIPOSOMES MEDIATED DUAL THERAPY OF AIDS RELATED OPPORTUNISTIC FUNGAL INFECTIONS AND AIDS
To deliver zidovudine (AZT) to asialoglycoprotein receptors, drug-containing galactosylated liposomes were prepared. Simultaneously, miconazole nitrate (MCZ) was entrapped in the outer liposomal bilayer of double liposomes for the treatment of opportunistic fungal infections. Galactosylated liposomes were entrapped in double liposomes. The galactose binding Ricinus communis lectin was used for the...
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PREPARATION AND EVALUATION OF MUCOADHESIVE MICROCAPSULES OF VERAPAMIL
Mucoadhesive microcapsules of verapamil, a peripheral vasodilator, used in the treatment of hypertension, angina pectoris, cardiac arrhythmia, have been prepared from sodium alginate, hydroxypropylmethyl cellulose- K4M & E5LV, Carbopol 934P using 10% w/v calcium chloride solution by ionic gelation method. Drug : polymer ratio was 1:1 in all formulations and polymer mixtures employed were 1:1, ...
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COMPARATIVE STUDY OF AZADIRACHTA INDICA LEAF POWDER AND ITS DIFFERENT EXTRACTS ON GLYCEMIC, INSULINEMIC AND LIPIDEMIC STATUS OF TYPE 2 DIABETIC MODEL RATS
The present study was carried out to investigate the effect of oral feeding of A. indica leaf (powder, aqueous and 80% ethanol extract) in STZ induced type 2 diabetic rats. Diabetes was induced by single intraperitoneal injection of STZ to 48hrs old pups and experiments were carried out three months later. For chronic experiment type 2 rats were divided into 5 groups: 1) Water control, 2) Glibencl...
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ADRENAL MYELOLIPOMA ASSOCIATED WITH CHOLELITHIASIS- A CASE REPORT
Adrenal myelolipomas are rare benign endocrinologically inactive tumor composed of mature adipose tissue and hematopoietic cells in varying proportions. Most lesions are small, unilateral and asymptomatic, discovered incidentally at autopsy or on imaging studies performed for other reasons. Its characteristic appearance on sonography and computed tomography enables preoperative diagnosis with a hi...
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DEVELOPMENT AND VALIDATION OF A HEADSPACE GAS CHROMATOGRAPHIC METHOD FOR THE DETERMINATION OF RESIDUAL SOLVENTS IN LEVETIRACETAM (API)
Levetiracetam is a new antiepileptic medication that is effective as adjunctive therapy in the treatment of partial onset seizures in adults and children 4 years of age and older with epilepsy. Levetiracetam is an antiepileptic drug available as a clear, colorless, grape-flavored liquid (100 mg/mL) for oral administration. It is the S-enantiomer of etiracetam, structurally similar to the prototypi...
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DEVELOPMENT AND VALIDATION OF UV SPECTROSCOPIC METHODS FOR SIMULTANEOUS ESTIMATION OF PARACETAMOL AND ZALTOPROFEN IN BULK AND TABLET FORMULATION
Two methods for simultaneous estimation of Pracetamol and Zaltoprofen in combined tablet dosage form have been developed. The first UV spectrophotometric method was a determination using the simultaneous equation method at 245 nm and 227 nm. The second UV spectrophotometric method is the Q – analysis (absorption ratio) method, which involves the formation of absorbance equation at 237.5 nm (isob...
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ROLE OF PROBIOTIC LACTOBACILLUS SPOROGENES IN THE TREATMENT OF ACUTE DIARRHOEA IN CHILDREN
Objective: To investigate the effectiveness of Lactobacillus sporogenes in the treatment of acute diarrhoea in paediatric population. Methods: In a prospective randomized open label comparative study, 62 children (1 month– 6 years) admitted to the Medical College Hospital for the treatment of acute diarrhoea, were included. The patients were randomised into two groups, control group (n =31) rece...
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