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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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7.

MULTI DIMENSION PROTEIN IMPACT MATRIX BASED PROTEIN SEQUENCE PREDICTION USING DATA MINING

Proteins are the most essential and versatile macromolecules of life, and the knowledge of their functions is a crucial link in the development of new drugs, better crops, and even the development of synthetic biochemicals such as biofuels. Experimental procedures for protein function prediction are inherently low throughput and are thus unable to annotate a non-trivial fraction of proteins that a...

A. Surendar

School of Electronics, Vignan’s University, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(2).427-34

427-434

3903

1420

7.

STABILITY INDICATING ASSAY METHOD DEVELOPMENT AND VALIDATION OF EDOXABANTOSYLATE MONOHYDRATE: A COMPREHENSIVE STUDY INVOLVING IMPURITIES ISOLATION, IDENTIFICATION AND DEGRADATION KINETICS DETERMINATION IN VARIOUS CONDITIONS

Objective: State of the art, robust and environmentally benign stability indicating assay method (SIAM) has been developed for model drug Edoxabantosylate (EDO) Methods: Successful RP-HPLC chromatographic method was accomplished on a CHROMBUDGET® 100-5-C18 column (250 mm × 4.6 mm, 5 μ) column using methanol and acetate buffer in the ratio of 53:47 having 2.9 pH and 10mM buffer strength. The deg...

S. Masani, P. Shah, S. Saroj and S. J. Rajput *

Faculty of Pharmacy, G.H. Patel Pharmacy Building, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.10(10).4477-87

4477-4487

3903

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51.

CIGARETTE SMOKE EXTRACTS INDUCE AND REPRESS GENES IN HUMAN EMBRYONIC LUNG CELLS

Disastrous effects of tobacco consumption on health remain in the focus of preclinical and clinical research. Exposures to tobacco smoke are closely connected to acute and chronic smoke lung dysfunctions and the effects are not restricted to airway inflammation processes. The facts that smoke exposure result in aberrant gene expression and changes in cellular phenotype resulting in clinical patter...

Klaus Braun*. Agnes Hotz-Wagenblatt , Manfred Wiessler, Rüdiger Pipkorn , Dorde Komljenovic , Wolfhard Semmler and Waldemar Waldeck

German Cancer Research Center (DKFZ), Dept. of Medical Physics in Radiology, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany

DOI: k.braun@dkfz.de

1059-1076

3901

1503

22.

EVALUATION OF RATIONAL USAGE OF ANTIMICROBIAL AGENTS IN THE MEDICINE DEPARTMENT AT TERTIARY TEACHING CARE HOSPITAL, GUJRAT

Background: Prescription of drugs which needs to be continuously assessed and refined according to disease progression. It is not only reflects the physician’s knowledge about drugs but also know the pathophysiology of diseases and attitude towards rational prescribing. Methods-: Retrospective study was carried out by collecting 350 prescriptions containing antimicrobial agents of the indoor ...

Vipul Prajapati* and J.D. Bhatt

Assistant professor, Department of Pharmacology, AMC MET Medical College, Ahmedabad-380008

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(3).865-73

865-873

3901

1565

27.

FLAVONE AND FLAVONE GLYCOSIDE FROM CICHORIUM INTYBUS LINN

Cichorium intybus Linn (Compositae) contains UV-absorbing metabolites. Studies on methanol extract of Cichorium intybus Linn by means of HPLC-UV, NMR, HPLC-MS resulted in isolation and identification of three previously unknown flavones glycosides: 5, 6, 7, 3′, 4′, 7′-hexahydroxy flavones-7-O-β-D-glucopyranoside (1), 3, 5, 7 – trihydroxy-3′,4′-dimethoxy-flavone-7-O-β-D-galactopyranos...

Gautam Patil* and Umesh Vishwkarma

Research Scholar, Natural Products Laboratory, Department of Chemistry, Dr. H. S. Gour Central University, Sagar-470003, Madhya Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(3).835-39

835-839

3901

2023

24.

EVALUATION OF EFFECTS OF PARTHENIUM HYSTEROPHORUS L., LEAVES EXTRACTS AGAINST MILK-INDUCED EOSINOPHILIA IN MICE

Parthenium hysterophorus L., compositae, also known as congress weed, carrot weed, star weed, reaching a height of 2 m in  weeks of germination, is believed to have entered India accidentally in the mid 1950's and is now available abundantly all over the India. Leaves are traditionally used in the treatment of asthma and allergy, leavas of the plant were extracted successively using aqueous and...

S. Rajasekaran

Department of Pharmacology, Jamia Salafiya Pharmacy College, Pulikkal, malappuram, Kerala, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1303-06

1303-1306

3901

1666

45.

A COMPARATIVE AND CORRELATIVE STUDY BETWEEN BLOOD AND SALIVARY GLUCOSE WITH BLOOD HbA1c IN TYPE 2 DIABETES

Diabetes is a non-communicable disease characterized by increased blood glucose. As regular monitoring of glucose and glycated hemoglobin (HbA1c) levels in diabetic individual’s blood causes psychological stress, development of a non-invasive technique to quantify glucose and HbA1c are essential. This study was carried out to compare and correlate the blood and salivary glucose and blood HbA1c l...

S. Harish and M. Shantaram *

Department of Studies and Research in Biochemistry, Mangalore University, Post Graduate Centre, Jnana Kaveri, Chikka Aluvara Kodagu, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(1).401-06

401-406

3901

1562

1.

BIOFILM INFECTIONS: A NEW THERAPEUTIC CHALLENGE

Biofilms are multicellular communities of bacteria. The ability to form biofilm is a universal attribute of bacteria and as bacteria can form biofilm in medical, industrial and environmental settings, it impacts human lives in many different ways. Bacteria undergo profound physiologic, morphologic and genetic changes as the transit from planktonic (free swimming, non-biofilm) form to surface attac...

Ashfaque Hossain

Department of Medical Microbiology, College of Medicine, University of Hail, PO Box.- 2440, Hail, Saudi Arabia

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(9).3286-95

3286-3295

3900

1701

40.

FORMULATION AND OPTIMIZATION OF FAST DISSOLVING TABLETS OF OLANZAPINE USING VACUUM DRYING TECHNIQUE BY 22 FACTORIAL DESIGN

The purpose of this research was to develop fast dissolving tablets of olanzapine and to optimize the processing variables. Tablets containing olanzapine, camphor, crosscarmellose, and directly compressible lactose were prepared by direct compression technique. The tablets were compressed and later exposed to vacuum. Sublimation of camphor from tablets resulted in superior fast dissolving tablets....

Sudhakar Sekar*, V. Malarvizhi and C. Vijaya

Faculty of Pharmacy, Masterskill University College of Health Sciences, Cheras- 43200, Selangor DE, Malaysia

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(6).1594-99

1594-1599

3900

1897

55.

GC–MS ANALYSIS AND IN-VITRO CYTOTOXIC ACTIVITY OF METHANOLIC EXTRACT OF ANTIGONON LEPTOPUS FLOWERS

The present study has been designed to evaluate the bioactive compounds and cytotoxic activity from the n-hexane fraction of methanolic extract of Antigonon leptopus flowers. The n-hexane fraction was analysed by GC-MS (Thermo GC-TRACE ultra ver.: 5.0, Thermo MS DSQ II) which revealed the presence of many diversified compounds including flavonoids, Vitamin D2 derivative, carbohydrates, amino acids...

S. S. Prajna , K. Sony Priya, S. Swarnalatha, P. Bhojaraju, L. K. Kanthal and K. Satyavathi*

Avanthi institute of pharmaceutical sciences, Cherukupally, Bhogapuram, Vizianagaram , Andhra Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.6(7).3083-87

3083-87

3900

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