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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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38.

COLON SPECIFIC DRUG DELIVERY OF LIQUISOLID PLUG OF SULFASALAZINE BY SINGLE CAPSULE WITH BILAYER COATING

The purpose of this study is to achieve colonic release of anti-inflammatory drug sulfasalazine used in the treatment of inflammatory bowel disease (IBD) to minimise side effects with a novel method of single capsule with bilayer coating. Sulfasalazine is an anti-inflammatory drug which acts topically on the inflamed colon to provide relief. In the present study a time and pH dependent colon targe...

S. Bhilegaonkar * and T. Palkar

Department of Pharmaceutics, P.E.S΄s Rajaram and Tarabai Bandekar College of Pharmacy Farmagudi, Ponda, Goa, India.

DOI: 10.13040/IJPSR.0975-8232.9(5).2019-26

2019-2026

3903

1850

45.

A COMPARATIVE AND CORRELATIVE STUDY BETWEEN BLOOD AND SALIVARY GLUCOSE WITH BLOOD HbA1c IN TYPE 2 DIABETES

Diabetes is a non-communicable disease characterized by increased blood glucose. As regular monitoring of glucose and glycated hemoglobin (HbA1c) levels in diabetic individual’s blood causes psychological stress, development of a non-invasive technique to quantify glucose and HbA1c are essential. This study was carried out to compare and correlate the blood and salivary glucose and blood HbA1c l...

S. Harish and M. Shantaram *

Department of Studies and Research in Biochemistry, Mangalore University, Post Graduate Centre, Jnana Kaveri, Chikka Aluvara Kodagu, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(1).401-06

401-406

3902

1565

27.

EVALUATION OF ANTHELMINTIC ACTIVITY OF DALBERGIA SISSOO ROXB.

The ethanolic extract of bark of Dalbergia sissoo Roxb. was investigated for its activity against Indian earthworms Pheretima posthuma and nematode Ascardi galli. Various concentrations (10, 20, 50 mg/ml) of ethanolic extract were tested, which involved determination of time of paralysis and time of death of the worms. It was compared with Piperazine citrate (15 mg/ml) and Albendazole (20 mg/ml) a...

Nitinkumar Upwar*, Roshan Patel , Naheed Waseem and Naveen Kumar Mahobia

Department of Pharmacognosy, Shree Leuva Patel Trust Pharmacy Mahila College, Patel Sankul, Chakkargadh road, Amreli-365601 (Gujarat) India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(1).171-74

171-174

3901

1783

7.

RESPONSES OR EFFECT OF CEREBRAL MALARIA ON PLATELET COUNT, PLATELET FACTOR – 3 AND PLATELET AGGREGATE AVAILABILITY IN CHILDREN

Background and Objective: Malaria, a formidable global parasitic infection represent a major health problem in tropical countries in terms of geographical spread, high morbidity, severe mortality especially among children. This study investigated platelet function’s role and its strength to make platelet factor 3 (PF-3) available for coagulation in children with cerebral malaria. Subjects and...

S. J. Ogboi *, S. P. Akpalu , I. A. Joshua and P.U. Agu

Public Health Laboratory, Department of Community Medicine, Faculty of Medicine, Ahmadu Bello University, Zaria, Kaduna State, Nigeria or Department of Life Sciences (Experimental Medicine MCA) and Public Health, University of Camerino, Via Madona Delle Carceri, 62032Camerino (MC) Italy

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(12).3096-99

3096-3099

3901

1604

38.

CHEMICAL COMPOSITION AND ANTIBACTERIAL ACTIVITY OF LEAF ESSENTIAL OIL OF EUGENIA COTINIFOLIA SSP. CODYENSIS (MUNRO EX WIGHT) ASHTON

The study was carried out to investigate the essential oil composition and antibacterial effects of Eugenia cotinifolia ssp. codyensis leaves. The fresh leaf essential oil was extracted hydrodistillation process using Clevanger apparatus. The compounds of the essential oil were analyzed using Gas Chromatography Mass Spectrometry (GC-MS) technique identified a total of 84 numbers of chemical consti...

R. Sarvesan , P. Eganathan *, J. Saranya and P. Sujanapal

Plant Tissue Culture and Bioprospecting Laboratory, M. S. Swaminathan Research Foundation, Taramani, Chennai, Tamilnadu, India

DOI: 10.13040/IJPSR.0975-8232.6(9).3981-85

3981-85

3901

1995

11.

IMPACT OF VITAMINS IN PREVENTION OF RISK FACTORS ASSOCIATED WITH TYPE-2 DIABETES MELLITUS

Diabetes mellitus is one of the most common metabolic disorders that cause micro and macro vascular complications. Because of additive effects of hyperglycaemia and hyperlipidaemia for cardiovascular disease, serum lipid and glucose level should be closely monitored in diabetes. Chronic Hyperglycaemia resulting from diabetes has profound effects on nearly every system of the body. The toxic effect...

V.K. Gupta*, Asha Pathak , Manoj Gahlot , R.C. Verma and C.V. Singh

Department of Pharmacology, Uttar Pradesh Rural Institute of Medical Sciences & Research , Saifai, Etawah, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(4).1335-47

1335-1347

3900

1617

12.

ANTIBACTERIAL EVALUATION OF MEDICINAL PLANTS USED BY KORKUS IN MELGHAT FOREST AGAINST GASTROINTESTINAL INFECTIONS

Use of plants as a source of traditional healing systems around the world that utilize herbal remedies is an important source for the discovery of new antimicrobials against resistant strains of bacteria. Medicinal plants have been a major source of therapeutic agents in Korkus from Melghat since time immemorial. Incredible knowledge of phytomedicine is acquired in non-coded form by these tribals ...

D. H. Tambekar* and B. S. Khante

Post Graduate Department of Microbiology, S. G.B. Amravati University, Amravati, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(3).577-83

577-583

3900

1826

54.

ANTIPYRETIC ACTIVITY OF THESPESIA POPULNEA FRUITS

In the present study, the alcoholic and aqueous extracts of Thespesia populnea were investigated for their antipyretic activity. Suspension of subcutaneous administration of brewer’s yeast in albino rat leads to pyrexia. Oral administration of extracts at a dose of 500 mg/kg body weight significantly reduced the elevated body temperature of rat. This antipyretic effect has been compared with ant...

E. N. Siju *, G. R.Rajalakshmi , Arun Shirwaikar

Assistant Professor and Head, Department of Pharmacology, Academy of Pharmaceutical Science, Pariyaram Medical College, Kannur, 670503, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(3).1087-89

1087-1089

3899

1559

24.

PHARMACOGENOMIC STUDIES OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) GENOTYPES IN SUSPECTED CAD PATIENTS

Recent studies have attempted to identify specific genes that contribute to cardiovascular health and disease. Response to various drugs like statins differs from individual to individual, due to polymorphic variations in drug metabolizing genes related to pharmacogenomics of the diseases. The aim of this study was to find out the association of Cholesteryl ester transfer protein (CETP) gene polym...

Javeed Ahmad Tantray , Y. Shiva Kumar and Kaiser Jamil*

Genetics Department, Bhagwan Mahavir Medical Research Centre, 10-1-1, Mahavir Marg, AC guards, Hyderabad- 500 004, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(10).3910-16

3910-3916

3899

2149

16.

A CASE CONTROL STUDY OF OXIDATIVE STRESS AND INFLAMMATION IN TUNISIAN PATIENTS WITH ISCHEMIC HEART DISEASE

Ischemic heart disease (IHD) is the major cause of morbid-mortality in most countries. The involvement of inflammation and oxidative stress (OS) in the development of atherosclerosis, ischemic cardiopathy triggering phenomen, has been investigated. The high sensitive C-reactive protein (hs_CRP) was measured in serum by immunoenzymatic method. Serum total homocysteine (Hcy) concentration was measur...

S. Khelil *, M. Ben-Hadj-Mohamed , M. Ben Dbibis , L. Khlifi, H. Chahed, S. Ferchichi, S. Ernez and A. Miled

Biochemistry Laboratory, Cardiologylogy Department, Farhat Hached hospital, Sousse, Tunisia

DOI: 10.13040/IJPSR.0975-8232.7(8).3314-21

3314-21

3899

1507