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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

IJPSR is indexed with Embase

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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18.

ANTIDIABETIC ACTIVITY OF 1-(4-(DIMETHYLAMINO)BENZYLIDENE)-5-(2-OXO INDOLIN-3-YLIDENE) THIOCARBOHYDRAZONE IN RATS

Objective: The present study was aimed to evaluate the antidiabetic activity of 1-(4-(Dimethylamino) benzylidene)-5-(2-oxoindolin-3-ylidene) thiocarbohydrazone i.e. a novel Isatin derivative diabetic rats. Methods: The antidiabetic activity of Isatin derivative was evaluated against alloxaninduced diabetes in rats. Diabetes in rats was induced by administration of alloxan monohydrate (120...

Ch. Tejasree , G. Kiran , G. Rajyalakshmi and A. Rama Narsimha Reddy*

Department of Pharmacology, Vaageswari College of Pharmacy 1, Beside LMD Police Station, Karimnagar-505481, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2738-43

2738-2743

2306

1204

8

1.

A CURRENT REVIEW FROM RECENT LITERATURE ON NOVEL SARS-COV-2 OUTBREAK

The outbreak of a novel coronavirus 2019 was traced back in China in late 2019, followed by their worldwide transmission as a pandemic. From January to August 2020, a total of 1,724 papers were published, where 125 were only published in August 2020, demonstrating the importance and need for current awareness and research to overcome this deleterious virus. This paper briefly highlighted the major...

C. Houacine *, G. A. Ibrahim, H. Alnasif, H. Suliman, I. Khan, I. Himoudy, N. K. Nasr, R. Mohamedkhair, R. Ballal, S. S. Yousaf and S. M. I. Elbashir

School of Pharmacy and Biomedical Sciences, Faculty of Clinical and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.

DOI: 10.13040/IJPSR.0975-8232.12(2).692-13

692-713

2306

1395

0

24.

EVALUATION OF ACUTE AND SUBACUTE TOXICITY OF ALCOHOLIC EXTRACT OF THE ROOTS OF TRAGIA CANNABINA IN RATS

The toxicity profile of alcoholic extract of roots ofTragia cannabina Family: Euphorbiaceae was studied in wistar rats. The multiple oral administration of extract at single dose of 100, 500, 1000, 2000 and 3000 mg/kg body weight for 24 hrs. did not produce sign of toxicity, behavioral appearance, change on a gross appearance. The sun-acute toxicity was determined by administration of graded dosag...

R. K. Patel *, S.B. Patel and J. G. Shah

Assistant Professor, Department of Pharmacology, Indukaka Ipcowala College of Pharmacy, New Vallabh Vidya Nagar, Anand, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(2).479-82

479-482

2305

992

3

40.

ANTIMICROBIAL ACTIVITY OF SOME ETHNOMEDICINAL PLANTS USED IN KASHMIR, INDIA

Antimicrobial activity of 11 ethnomedicinal plant extracts was evaluated against five bacterial strains (Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Proteus vulgaris) and one fungal strain (Candida albicans). Plants were collected from different regions of Kashmir Valley and the ethnomedicinal data were gathered from traditional healers and elders of the stu...

G. Guna

Department of Botany, Islamia College of Science and Commerce, Srinagar, Jammu & Kashmir, India.

DOI: 10.13040/IJPSR.0975-8232.9(12).5339-43

5339-5343

2305

951

0

2.

A REVIEW ON ANTIMICROBIAL POTENTIAL OF SULFONAMIDE SCAFFOLD

Sulfonamides, sometimes called sulfa drugs, are the first drug that is largely employed and systematically essential for preventive and chemotherapeutic agents against various bacteria. Sulfonamides possess a wide range of pharmacological activities such as Oral hypoglycemic, antileprotic, anti-epileptic, anti-hypertensive, anti-bacterial, anti-protozoal, anti-fungal, antiretroviral, non-peptidic ...

P. A. Petkar and J. R. Jagtap *

Department of Pharmaceutical Chemistry, Pune District Education Association’s Seth Govind Raghunath Sable College of Pharmacy, Saswad, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.12(5).2535-47

2535-2547

2303

1290

9

32.

SYNTHESIS OF SILVER NANOPARTICLES USING SWERTIPUNICOSIDE AND ITS ACTIVITY ON HUMAN BREAST CANCER CELL LINE (MCF-7)

In the current study, synthesis of silver nanoparticles (AgNPs) using swertipunicoside was tested against human breast cancer cell line (MCF-7). The swertipunicoside was tested against the normal cell line such as vero cells to find out the toxicity of the compound. The synthesized AgNPs were characterized using UV-visible spectroscopy, X-ray powder diffraction (XRD), fourier-transform infrared sp...

S. Sivaranjani and C. Arulvasu *

Department of Zoology, University of Madras, Guindy Campus, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.9(11).4775-83

4775-4783

2302

914

0

18.

FORMULATION, NUTRITIONAL, SENSORY, ANTIOXIDANT ACTIVITY AND SHELF LIFE STUDIES OF INSTANT SOUP MIX

In today’s modern lifestyle, there is an increase in the development of various instant food products. To meet consumer requirements, the food choice will depend on several factors. The present study was aimed with the objective to formulate a value-added instant soup mix with nutritional and sensory charac-teristics. Further, the prepared instant soup mix was subjected to antioxidant and shelf ...

Priti and K. Prameela *

Department of Biotechnology, GITAM Institute of Technology, GITAM University, Visakhapatnam, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(12).6114-23

6114-6123

2301

1256

2

58.

TEMPERATURE STRESS MEDIATED CONSEQUENCES ON PHYSIOLOGY AND SECONDARY METABOLITES OF DATURA STRAMONIUM (L.)

Datura stramonium (L.), a multipurpose plant of Himalayan regions which possess antiseptic, sedative, antidiarrhoeal properties used for treating various diseases which include treatment of ulcer, skin disorder, jaundice, fever, heart diseases, etc. To evaluate the temperature stress-mediated morphological, physiochemical, and antioxidative defense in Datura stramonium, plants were subjected to di...

Shriya, M. Sharma *, A. Kumari and S. Choudhary

Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).3085-91

3085-3091

2300

820

6

25.

PHYTOCHEMICAL STUDIES, FTIR AND GC-MS ANALYSIS OF HARDWICKIA BINATA ROXB. (FABACEAE / CAESALPINIACEAE)

Hardwickia binata belongs to family Fabaceae / Caesalpiniaceae and commonly known as ‘Anjan’. The present study includes phytochemical screening, FTIR and GC-MS analysis. Shade dried powdered leaves, seed and husk of H. binata extracted in petroleum ether, chloroform, ethyl acetate, acetone, methanol, ethanol, distilled water using Soxhlet apparatus and used for phytochemical analysis. Crude p...

S. V. Deshmukh * and N. A. Ghanawat

Department of Botany, Yashavantrao Chavan Institute of Science, Satara, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.11(1).233-40

233-240

2298

982

0

13.

CAPSAICIN (C18H27NO3) AND PHYTOL (C20H40O) FROM CAPSICUM ANNUM L. LEAF DOCKED AGAINST SALIVARY GLAND PROTEIN OF CULEX QUINQUEFASCIATUS

Overpopulation leads to rapid urbanization, and industrialization has directed an unplanned town expansion with no sanitary facilities and proper wastewater disposal arrangements drains in the pond. Mosquitoes create a significant public health problem in India and serve as vectors for transmitting various diseases like malaria, filariasis, dengue, chikungunya, etc., to humans. This results in the...

C. A. Annapoorani *, G. Indumathi and K. Manimegalai

Department of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2748-53

2748-2753

2296

795

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