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SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF N-ARYLQUINOXALIN-2-AMINES BEARING BENZIMIDAZOLE DERIVATIVES
In the present study reports synthesis and development of 3-Chloro – N - ((5-chloro-1-tosyl-1H-benzo [d] imidazol – 2 - yl) methyl) - N arylquinoxalin-2-amines (5a-e) from 3-chloro-N-p-tolyl quinoxalin -2-amine (3) condensed with proporgyl bromide followed by adding 4-chloro-N1-tosylbenzene-1,2-diamine,by adopting simple procedure. All titled compounds were screened for their anti bacterial ac...
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IN-VITRO AND EX-VIVO STUDIES ON SYNERGISTIC EFFECTS OF LIMONIA ACIDISSIMA AND APPLE CIDER VINEGAR ON ANTI-UROLITHIATIC ACTIVITY
Kidney stones are aggregations of minerals such as calcium, oxalate, phosphates, uric acid, cysteine, etc. which can obstruct any part of the urinary system. This can turn fatal if left untreated as the major route of excretion is blocked causing the toxicity level to rise in the body which might lead to organ failure, coma and death. Limonia acidissima (wood apple) and Apple cider vinegar were fo...
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A PRELIMINARY EVALUATION OF ANTIBACTERIAL AND TOXIC POTENTIALS OF P. GUINEENSE SWARTZ. FRUIT PULP FROM DIFFERENT STAGES OF RIPENESS
Psidium guineense Swartz is a shrub native to Brazil. It is consumed in natura or in the form of pulp, which presents a high content of C vitamin and proteins. The chemical prospection of the aqueous extracts from unripe and mature pulp revealed the presence of tannins and flavonoids. The extracts demonstrated moderate antibacterial activity against the most of strains tested, and the best result ...
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EVIDENCE BASED STUDY OF EFFECT OF SWARNA YOGA (GOLD FORMULATIONS) IN CHILDREN: A SYSTEMATIC REVIEW
Background: In the field of pediatrics, a number of herbo-metallic preparations are available which tend to enhance immunity in children. Various Ayurveda texts have mentioned these preparations, especially gold formulations like Swarna Prashan, Suvarnabindu, Suvarna Vacha, Kumarabharana Rasa etc. in children, and many clinical studies have also been published to establish their safety and efficac...
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ISOLATION OF ENDOPHYTIC FUNGI FROM DIPTEROCARPUS GRANDIFLORUS BLANCO AND EVALUATION OF XYLANASE ENZYME ACTIVITY FROM FERMENTATION BROTH
Xylanase enzyme, one example of secondary metabolites generated by the endophytic microbes was an enzyme which degrades Xylan. The current research study was focused on isolation of endophytic fungi from Dipterocarpus grandiflorus Blanco that produced xylanase enzyme and evaluation of this enzyme activity. Isolation of endophytic fungi from Twigs of D. grandiflorus Blanco were performed via direct...
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ANTIOXIDANT POTENTIAL OF THE WHOLE PLANT EXTRACT OF MOLLUGO PENTAPHYLLA LINN. ON ETHANOL INDUCED LIVER DAMAGE
The potential antioxidant effect ethanol induced liver damage was investigated using crude methanolic extract of the whole plant of Mollugo pentaphylla Linn. The standard drug used was ascorbic acid mg / kg/day. Serum cholesterol, triglycerides aspartate amino transferase (AST) and alanine amino transferase (ALT) levels were measured as antioxidant indicators. There was a significant reduction...
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EFFECT OF CHITOSAN COATING ON THE PHYSIOCHEMICAL CHARACTERISTICS OF GEFITINIB LOADED NANOLIPOSOMES
In the present work the nanoliposomes prepared by using REV and MEU methods were coated with different concentration of chitosan solutions. The main objective behind this work was to assess the physical properties, stability and in vitro release of uncoated and chitosan coated nanoliposomes of gefitinib. The existence of a covering on the exterior of nanoliposomes was confirmed by the modification...
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IDENTIFICATION OF INTER SPECIES GENETIC VARIABILITY BETWEEN TWO MORPHOLOGICALLY SIMILAR SPECIES OF WITHANIA THROUGH PROTEIN AND RAPD MARKERS
The two species of Withania i.e. Withania obtusifolia and Withania somnifera were usually misinterpreted because of their co-existence in mixed populations. The present investigation involves analyzed of interspecific relationship between these two species. A careful morphological, anatomic and phytochemical, identification of the two species has led to the findings that there was a slight variati...
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PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT ACTIVITY STUDIES OF LEAF OF BRASSICA JUNCEA VAR RUGOSA THROUGH SEQUENTIAL SOLVENT EXTRACTION
Objectives: To find out different qualitative and quantitative phytochemical properties, it’s in-vitro antioxidant properties and peroxidase activity of Brassica juncea var. Rugosa (record tro- 50197928) with fresh and sequential solvent extracts. Methods: The leaf sample of Brassica juncea var. rugosa was collected from Manipur and the sample was dried. The dried powder was extracted using Soxh...
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PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF DIOSPYROS EBENUM J. KOENIG EX RETZ., LEAVES EXTRACT
Phytochemical screening and antioxidant activities with different solvents extracts of Diospyros ebenum were investigated. The phytochemical screening of this study indicated the presence of alkaloids, carbohydrates, coumarins, flavonoids, glycosides, phenols, proteins, saponins, steroids, tannins, and terpenoids. The methanolic extract of D. ebenum was significantly higher phenolic content when c...
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