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COMPARATIVE STUDY OF LEVOCETIRIZINE ELIMINATION BY PRISTINE AND POTASSIUM PERMANGANATE MODIFIED ACTIVATED CHARCOAL
The elimination capacity of pristine powder activated charcoal PAC and powder activated charcoal modified with potassium permanganate MPAC to remove levocetirizine drug was investigated. The activated charcoal was impregnated with KMnO4 100 mg/L in order to improve the surface properties. The influence of concentration, time and pH on the adsorption of levocetirizine drug was conducted by means of...
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THE EFFECT OF MEDIA AND FERMENTATION CONDITION TOWARD ANTIBACTERIAL ACTIVITIES OF BACILLUS SP. DA11 ASSOCIATED WITH SARCOPHYTON SP.
The emergence of antibiotic-multidrug resistant microorganisms is an essential issue in the health sector. Consequently, the exploration of new antimicrobial compounds from many promising resources is urgently required. Soft coral-associated bacteria are potential as antimicrobial compound producers. This study aims to get the best medium and fermentation conditions in the production of secondary ...
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685
COMPARATIVE STUDY ON FILTER EFFICIENCY OF DIFFERENT BRANDS OF CIGARETTES BY MICROSCOPIC AND SPECTROSCOPIC TECHNIQUES
Internationally there has been research on large scale for determination of efficiency of cigarette filters but in India it still remains a topic of discussion. Being the second largest consumers of tobacco and tobacco products and one of the largest and fastest growing consumers of cigarettes, such studies need to be undertaken at a greater level to assess the risk and hazards of cigarette smokin...
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FORMULATION AND EVALUATION OF CETUXIMAB LOADED POLYMERIC NANOPARTICLES
Nanoparticles speak to one of the appealing choices in the compelling treatment of tumor chemo-treatment. In the present work, definition, and improvement of a novel Cetuximab (MTX)- stacked biodegradable nanoparticles utilizing poly(D, L-lactide-co-glycolide) (PLGA) was done. Nanoparticles stacked with anticancer operators can effectively build sedate focus in malignancy tissues and furthermore a...
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PROBIOTIC POTENTIALS OF LACTIC ACID BACTERIA ISOLATED FROM VAGINAL SWABS ON SELECTED GENITAL PATHOGENS
Eudragit RS100 microcapsules containing Aspirin as a model drug was prepared using solvent evaporation technique. The drug was dispersed in the organic phase and poured into the aqueous phase with stirring until microcapsules formation. The product was collected by filtration and air dried. The particle size analysis of the products was done and normal distribution curve showed for the same size r...
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PHARMACOLOGICAL EVALUATION OF SOME NOVEL THIENO 1, 2, 3-TRIAZINES-4-ONES FOR ITS ANALGESIC ACTIVITY
The analgesic activity was assessed using hot plate method, formalin induced paw licking test, acetic acid induced writhing test. Preliminary investigations were carried out with water, DMSO and chloroform for solubility. For analgesic activity 1, 2, 3- triazine-4-ones series of compounds CP1, CP2, CP3 showed significant increase in jumping time of mice in hot plate method at only higher dose leve...
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LC-MS ANALYSIS OF BIOLOGICALLY ACTIVE EXTRACTS FROM POLYHERBAL FORMULATION TO TREAT PSORIASIS
The present study deals with the identification of the phytochemical compounds in ethanol, acetone and benzene extracts from polyherbal formulation composed of the bark of Ficus religiosa, the root of Smilax chinensis, seeds of Nigella sativa, the fruit of Emblica officinalis, Terminalia chebula and Terminalia bellerica which is used to treat psoriasis. The bioactive components of different extrac...
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PREVENTIVE EFFECTS OF CARISSA CARANDAS FRUIT EXTRACT AGAINST DMBA INDUCED SKIN CARCINOGENESIS STUDIES IN SKIN OF SWISS ALBINO MICE: MORPHOLOGICAL AND HISTOPATHOLOGICAL STUDY
Antitumor and antioxidative efficacy of Carissa carandas extract (CCE) was investigated in this study against skin carcinogenesis which was initiated by a single topical application of 7, 12-dimethyl-benz(a)anthracene (100 mg / 100 ml acetone in 1% acetone) and two weeks, later promoted by repeated treatment of TPA (Croton oil) for 16 weeks (in 1% acetone) in Swiss albino mice. Oral administration...
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ANTI-OXIDATIVE, ANTIBACTERIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF ARTOCARPUS HETEROPHYLLUS SEED EXTRACTS
Artocarpus heterophyllus is an evergreen tree cultivated and consumed throughout Nepal; however, its seed has been neglected as compared to the fruit. The sample was screened for phytochemical evaluation, and general tests, DPPH activity, antibacterial activity, and total flavonoid content was also measured. Also, the potential of its use as functional food was highlighted. Phytochemical analysis ...
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FORMULATION AND EVALUATION OF HYDROTROPIC SOLID DISPERSION OF ELUXADOLINE
In the present research, newly developed hydrotropic solid dispersion technique utilizing the use of aqueous solvent was developed, to avoid the utilization of organic solvent and all together declining their toxicity. This technology was employ intended for preparing the dispersion of Eluxadoline by using new hydrotropic agent sodium caprylate with using different ratio. Prepared formulations wer...
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