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ANTIMICROBIAL ACTIVITY OF SILVER NANOPARTICLES FROM SUBSTITUTED AND UNSUBSTITUTED IMIDAZOLIUM IONIC LIQUIDS
Nanotechnology is an innovative and escalating field that has made its contribution to all spheres of human life. Conventional synthesis of nanoparticles suffers from serious problems like high temperature, poor yield, longer reaction time, and use of toxic and highly sensitive compounds. Green synthesis of nanoparticles is an emerging field which is known to eliminate / minimize the aforementione...
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INDUCTION OF ROOTS AND IN-VITRO REGENERATION OF NOTHAPODYTES NIMMONIANA GRAHAM FROM EMBRYO CULTURES
The present study was aimed to develop the effective protocol for induction roots and in-vitro regenerated plants from embryo culture of Nothapodytes nimmoniana. Excised embryos were sterilized under the aseptic condition and cultured on L2 medium fortified with different concentration (0.5 - 3 mg/L) and the combination of auxins and cytokinins. Maximum shoot initiation was observed in BAP (2 mg/L...
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IDENTIFICATION AND QUANTIFICATION OF OLEANOLIC ACID FROM CYCLEA PELTATA BY HIGH-PERFORMANCE THIN LAYER CHROMATOGRAPHY (HPTLC) METHOD
Objective: To identify and quantify oleanolic acid from the roots of cyclea peltata by HPTLC method. Methods: The Plant cyclea peltata is a perennial herb from Menispermacae family. The powdered roots of plant cyclea peltata were extracted with methanol. Methanolic extract prepared separated with n-butanol, chloroform, and ethyl acetate as total saponin, total alkaloid and phenolic compound fracti...
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PRELIMINARY PHYTOCHEMICAL SCREENING AND GC-MS ANALYSIS FOR IDENTIFICATION OF BIOACTIVE COMPOUNDS FROM ABUTILON FRUTICOSUM GUILL AND PERR. A RARE AND ENDEMIC PLANT OF INDIAN THAR DESERT
Present work was aimed to determine, identify, and characterize the bioactive chemical compounds from methanolic leaves extract of Abutilon fruticosum by GC-MS analysis. Fresh disease-free leaves were collected shade dried and powdered for extraction with HPLC grade methanol. Preliminary phytochemical screening of methanolic leaves extract was performed using standard methods to determine the pres...
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FORMULATION AND CHARACTERIZATION OF ECONAZOLE NITRATE LOADED TRANSFERSOMAL GEL FOR ANTIFUNGAL ACTIVITY
The aim of the present work is to formulate and characterize Econazole nitrate (EN) loaded transfersomal gel for antifungal activity. EN is a broad-spectrum imidazole antifungal agent that belongs to BCS Class II. Due to poor solubility, EN is incompletely absorbed after oral administration and bioavailability vary among individuals. Topical treatment of fungal infections is usually preferred, but...
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ETHANOLIC SEED EXTRACT OF AFRAMOMUM MELEGUETA PROTECTS AND PRESERVES THE FUNCTIONS AND MICROARCHITECTURE OF THE OVARY OF ADULT FEMALE WISTAR RATS AGAINST PARAQUAT INDUCED TOXICITY
Aframomum melegueta (Alligator pepper) is a tropical plant that belongs to the Zingiberaceae (Ginger) family, consumed for its culinary and health benefits. This study investigated the therapeutic efficacy of ethanolic seed extract of Aframomum melegueta at ameliorating paraquat-induced ovarian toxicity in rat models. Thirty female Wistar rats were divided into control and five test groups (n=5). ...
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FORMULATION & EVALUATION OF HERBAL TRANSDERMAL PATCH OF CENTELLA ASIATICA & LIQUORICE TO STUDY WOUND HEALING ACTIVITY
Wound healing remains a significant challenge in modern medicine, necessitating the exploration of innovative therapeutic strategies. Centella asiatica, a widely recognized medicinal herb, has garnered attention for its potential wound healing properties. This study aimed to investigate the efficacy of a Centella asiatica transdermal patch in promoting wound healing. These results suggest that the...
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THE PRACTICE OF SELF MEDICATION IN DIARRHEA AMONG SECOND YEAR MEDICAL STUDENTS IN A TERTIARY CARE HOSPITAL IN JHARKHAND
Over the counter (OTC) drugs are drugs easily available without the prescription of a registered medical practitioner (RMP) and self-mediation practices of these drugs are very common in medical students especially in diarrhea which mostly requires dehydration therapy only. But very few reports are available regarding the use of OTC antidiarrhoeal drugs. The aim of the study was designed to assess...
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EUPHORBIA FUSIFORMIS: A RARE, VERSATILE SPECIES – A REVIEW
Euphorbia fusiformis Buch.-Ham.ex D. Don, (Synonym: Euphorbia acaulis Roxb) is an infrequent, medicinal, geophytic herb of the family Euphorbiaceae. It is distributed only in few pockets of India, Nepal, Africa and China. In India, it is found to grow in Maharashtra, Karnataka, Gujarat, Goa, Rajasthan, Andhra Pradesh, Madhya Pradesh, Uttar Pradesh, Bihar, Tamil Nadu and West Bengal. Traditionall...
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STORAGE OF WORKING STANDARDS IN POLYPROPYLENE CONTAINERS, ITS EFFECT, CONTAMINANTS AND IMPACT ON ANALYSIS ON LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROSCOPY
Authorspropose a method to determine the contamination caused during the storage of colchicine stock solution, which will be helpful for the bioanalytical scientists. The process of identification of impurities, exceptionally in this case, started from the point of optimization of the compound, where in the parent ion was not detected and instead an unknown mass is being interpreted by the detecto...
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