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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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10.

IDENTIFICATION AND QUANTIFICATION OF OLEANOLIC ACID FROM CYCLEA PELTATA BY HIGH-PERFORMANCE THIN LAYER CHROMATOGRAPHY (HPTLC) METHOD

Objective: To identify and quantify oleanolic acid from the roots of cyclea peltata by HPTLC method. Methods: The Plant cyclea peltata is a perennial herb from Menispermacae family. The powdered roots of plant cyclea peltata were extracted with methanol. Methanolic extract prepared separated with n-butanol, chloroform, and ethyl acetate as total saponin, total alkaloid and phenolic compound fracti...

L. B. Bhagure and H. D. Une *

Department of Pharmacology, Y. B. Chavan College of Pharmacy, Rouza Bagh, Aurangabad, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.10(11).4899-06

4899-4906

3407

1622

57.

DEVELOPMENT EVALUATION AND CHARACTERIZATION OF LOSARTAN POTASSIUM BUCCAL PATCHES USING HYDROPHILIC POLYMERS

Among different routes of drug delivery buccal route is an attractive alternate for drug administration which provides improved patient compliance and increase bioavailability of drugs undergoing extensive hepatic first pass metabolism. The present research work focussed on development, evaluation and characterization of buccal patches of losartan potassium using mucoadhesive hydrophilic polymers ...

S. N. R. Adhikari * and S. Panda

Department of Pharmaceutics, Seemanta Institute of Pharmaceutical Sciences, Mayurbhanj, Odisha, India.

DOI: 10.13040/IJPSR.0975-8232.9(12).5474-84

5474-5484

3406

1559

13.

MATHEMATICALLY DESIGNED BIOPROCESS FOR RELEASE OF VALUE ADDED PRODUCTS WITH PHARMACEUTICAL APPLICATIONS FROM WASTES GENERATED FROM SPICES INDUSTRIES

A mathematical model optimizing bio-physico-chemical pre-treatment of steam exploded Piper nigrum, and Syzygium aromaticum lignocellulosic biomass waste was developed. The model was developed using, RSM, involving central composite face-centered design (CCD) with six parameters, three levels and 40 runs, at 95% confidence level. Six parameters optimized were quantity of each enzyme (a) Cellulase (...

M. Singh and S. Vats *

Institute of Biosciences and Technology, Shri Ram Swaroop Memorial University, Lucknow, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(1).130-38

130-138

3406

1479

7.

CHALCONE – PROMISING ENTITY FOR ANTICANCER ACTIVITY: AN OVERVIEW

Chalcones are naturally occurring compounds with a wide range of biological activities along with an anticancer activity through various mechanisms. It is also known as aromatic ketone, which creates a central core for different essential biologically active compounds. The literature on anticancer chalcones shows the use of various prolonged approaches like structural manipulation and replacement ...

A. A. Alman *, K. Daniel and S. G. Killedar

Department of Pharmacy, B. R. Nahata College of Pharmacy, Mandsaur University, Mandsaur, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(5).2027-41

2027-2041

3406

2254

16.

FORMULATION DEVELOPMENT AND EVALUATION OF NANOGEL LOADED WITH MONTELUKAST SODIUM NIOSOMES

Niosomes are vesicular carriers in the drug delivery system that are reported in the seventies. They are formed by self -assembly of non –ionic surfactant and cholesterol upon hydration with aqueous media resulting in lamellar structures that encapsulates both polar and non polar drugs. In the present research work, Montelukast sodium niosomes were prepared by using non –ionic surfactant span ...

B. R. Rane *, R. S. Patil and A. S. Jain

Shri D.D. Vispute College of Pharmacy and Research Center, Panvel, Raigad, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.12(8).4208-21

4208-4221

3406

3396

21.

SYNTHESIS, SPECTRAL CHARACTERIZATION AND DNA BINDING PROPERTIES OF LANTHANIDE (III) COMPLEXES WITH 2-FORMYLPYRIDINE NICOTINOYLHYDRAZONE

The lanthanide (III) complexes of general formula of [Ln(FPNH)2(NO3)](NO3)2.nH2O (where, Ln = La, Ce, Pr, Nd, Sm; FPNH = 2-formylpyridine nicotinoylhydrazone, n = 0, 2 and 5 for La/Ce/Pr, Sm and Nd complexes, respectively) were synthesized under mild reaction conditions with excellent yields. The complexes were characterized based on elemental analysis, molar conductivity, and infrared spectroscop...

B. Moksharagni and K. H. Reddy*

Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu , Andhra Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.8(8).3379-84

3379-3384

3405

1623

43.

EFFECT OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS ON SERUM AMYLASE AND LIPASE IN PATIENTS WITH HYPERTENSION

Introduction: Angiotensin-converting enzyme (ACE) inhibitors are a class of potential drugs used as first-line agents for the treatment of hypertension and heart failure in physiologically young patients despite its side effects. Apart from the other common side effects, they are known to induce bradykinin release which alters vascular permeability leading to pancreatic edema resulting in intrapan...

N. Ojha, J. A. Ebens and P. Shanmugasundaram *

Department of Pharmacy Practice, School of Pharmaceutical Sciences, VISTAS, Pallavaram, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(5).2412-16

2412-2416

3403

1433

18.

IN-VIVO APPRAISAL OF PHARMACOLOGICAL ACTIVITY OF BACOPA MONNIERI AND ITS HPLC ANALYSIS FOR BACOSIDE A

Bacopa monnieri is a herb, known to possesses various pharmacological and medicinal properties. Aim: The objective of the study was to analyse the activity of Bacopa monnieri as an antipyretic, analgesic and anti-ulcerogenic agent. Methods: Indomethacin was used as the standard of comparison for this study. Animals were arbitrarily separated into three groups of six animals in each group. The firs...

S. E. Prince *, A. P. Das and G. Arumugam

Department of Biomedical Sciences, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(5).2244-49

2244-2249

3403

1307

29.

AN ASSOCIATIVE INVESTIGATION BETWEEN TSH AND SERUM LIPID CONCENTRATIONS IN THE POPULATION OF BHOPAL, INDIA

The association between TSH and serum lipids in people with no apparent thyroid dysfunction is less understood. We have investigated the association between normal thyroid function, defined as TSH within the reference range and serum lipids concentrations. Cross-sectional, population based study with 1785 individuals without known thyroid dysfunction. We calculated mean concentrations of total ser...

Rakesh Kumar Patidar, Ranjeeta Raghuwanshi, Preeti Sharma, Vinod singh*

Department of Microbiology, Barkatullah University, Bhopal, Madhya Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(4).1112-15

1112-1115

3402

1524

63.

MOLECULAR DOCKING AND IN-SILICO ADME STUDIES OF NOVEL DERIVATIVE OF ERLOTINIB IN GLIOMA

Glioblastoma (GBM), with restricted therapy alternatives, is a catastrophic primary brain tumor. The receptor of the epidermal growth factor receptor (EGFR) in glioblastomas is recurrently enhanced, over articulated, or mutated, but up to 20 percent of GBM patients find it to be responded to kinase inhibition of EGFR. Several inhibitors of EGFR tyrosine kinase (TKI) failed clinically, due in part ...

D. Tripathi and S. Imran *

Department of Biotechnology, Faculty of Engineering and Technology, Manav Rachna International Institute of Research and Studies, Faridabad, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.11(5).2498-03

2498-2503

3402

1450