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IN-VITRO ANALYSIS TO ANALYSE THE DISINTEGERATION PROPERTY OF PRF WHEN TREATED WITH VARIOUS CONCENTRATION OF TRANEXAMIC ACID
Aim: To assess whether Tranexamic acid has any effect in inhibiting degradability of PRF membrane and also to compare the degradability of PRF at different concentrations of Tranexamic acid (200 mg, 150 mg and 50 mg). Material and Methods: The degradability of PRF membrane was compared between various concentrations of Tranexamic acid such as 200 mg, 150 mg, 50 mg against negative control of phosp...
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FORMULATION DEVELOPMENT AND EVALUATION OF NANOGEL LOADED WITH MONTELUKAST SODIUM NIOSOMES
Niosomes are vesicular carriers in the drug delivery system that are reported in the seventies. They are formed by self -assembly of non –ionic surfactant and cholesterol upon hydration with aqueous media resulting in lamellar structures that encapsulates both polar and non polar drugs. In the present research work, Montelukast sodium niosomes were prepared by using non –ionic surfactant span ...
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PHARMACEUTICAL SCIENCE BRINGS GENETICS AND IMMUNOLOGY TOGETHER TO EVOLVE A NEW DIMENSION IN TREATING CHILDHOOD CANCER: A REVIEW
Surgery, chemotherapy and radiation therapy has been the cornerstone of cancer management for decades. Since a decade or so, targeted therapies by way of Imatinib and Trastuzumab arrived that specifically target cancer cells and reply on specific molecular changes to identify them. These are in fact the standard treatment at present in several forms of cancer. But now in recent times, the fifth pi...
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ASSESSMENT OF PRESCRIBING PATTERN OF ANTIEPILEPTICS IN PAEDIATRIC IN-PATIENTS OF A TERTIARY CARE HOSPITAL
Purpose: To study the prescribing pattern of AEDs for a different type of seizures in the pediatric population and disease conditions other than epilepsy and to identify the drug interactions with the use of AEDs among the study population. Methods: This six months long prospective observational study was conducted at in-patient wards of JSS Hospital. The case sheets of all in-patients were review...
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ISOLATION, IDENTIFICATION AND QUANTIFICATION OF BIOACTIVE COMPOUNDS FROM AMARANTHUS HYPOCHONDRIACUS LEAF EXTRACT: A VITAL SOURCE OF POTENT NATURAL ANTIOXIDANTS
In this study we aimed at isolation, identification, and quantification of two phenolic compounds reported for the first time in leaves of Amaranthus hypochondriacus. A non targeted GC-MS metabolite profiling of hexane extracts of amaranth leaves was done which indicated the presence of major phenolic compounds. Two alkylated phenols namely 2,4-di-tert-butyl phenol (A) and 3-(3,5-di-tert-butyl-4-h...
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COMPREHENSIVE STUDY OF ACACIA LEUCOPHLOEA (ROXB.): TRADITIONAL USES, PHYTOCHEMISTRY AND PHARMACOLOGICAL SIGNIFICANCE
Herbal remedies have been utilized in medical practice for thousands of years and are recognized notably as a significant and widely available resource for health treatment. Traditional botanicals and herbal supplements have been deemed to be mild, non-toxic and even safe due to their natural nature. Acacia leucophloea (Roxb.) Willd. belongs to the family Mimosaceae, recognized as a diverse reso...
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A COMPARATIVE STUDY OF DOT AND SAT IN RURAL TERTIARY CARE HOSPITAL: A TWO YEARS RETROSPECTIVE STUDY
Directly observed therapy (DOT) of tuberculosis patients talking their drugs is supposed to improve treatment completion and outcome .we compared DOT and Self Administered therapy (SAT), in which patients on the same drug regimen are not, observed taking their pills, to assess the effect of each on the success of tuberculosis treatment. This was the two year (2010 and 2011) retrospective study of ...
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EFFECTS OF ANTIMICROBIAL ACTIVITY OF VITIS VINIFERA (RED GRAPE) AND CAMELLIA SINENSIS (GREEN TEA) EXTRACTS
Food and nutrients play vital role in normal functioning of the body. The samples selected for this study were Ethanolic extract of Red grape seed, Ethanolic extract of green tea leaves, Commercially available grape seed extract / Isotretinion tablet, green tea extract , Vitamin A and E tablets. The Nutraceutical effects of grape seed extract and green tea extract was analyzed. The antimic...
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ASSESSMENT OF ANTIOXIDANT ACTIVITY OF DIFFERENT EXTRACTS OF ANNONA RETICULATA (L.)
Objective: The present study has been carried out to evaluate the antioxidant property of different extracts obtained from successive extraction of Annona reticulata L. leave with solvents of increasing polarity. Effort also has been made to estimate the flavonoid and phenolics content of the extracts. Method: The antioxidant activity has been studied in-vitro by using DPPH, hydrogen peroxide and ...
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FOUR MOST LIFE THREATENING UROGENITAL CANCER AND ITS MANAGEMENT
Now a day’s urogenital cancer is the life threatening disease in worldwide, among them most four life threatening urogenital cancers are kidney cancer, bladder cancer, prostate cancer and testicular cancer. Kidney cancer or renal cell carcinoma (also called adenocarcinoma) is a disease in which malignant cancer cells are found in the living of tubules (renal epithelium). The kidney cancer has th...
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