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DESIGN, DEVELOPMENT AND EVALUATION OF TOPICAL ANTIINFLAMATORY HERBAL GEL
The objective of the present investigation was to develop topical curcuminoids containing gel as an anti-inflammatory. The first gel base was prepared by using various different concentrations of Carbopol 934, Propylene glycol 400, Methylparaben, Propylparaben, and required amount of distilled water. The optimized base was selected for the incorporation of different concentrations of curcuminoids ...
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SEMECARPUS ANACARDIUM LINN: AN ETHNOMEDICAL, PHYTOCHEMICAL AND PHARMACOLOGICAL REVIEW
Semecarpus anacardium Linn. (Family Anacardiaceae), generally known 'Ballataka' or' Bhilwa', is a factory well-known for its medicinal value in ayurvedic and siddha system of the drug; it's also used for non-medicinal purpose like marking of cloth, hair color, etc. since ancient time. Phytochemical analyses of Semecarpus anacardium nut shows that, its nut contains a variety of biologically active ...
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IN-VIVO ANTIFUNGAL ACTIVITY OF THE AERIAL PART OF ANVILLEA RADIATA BY USING A NEW METHOD OF STORAGE BY COATING GRAIN
The aim of the present study is to evaluate the antifungal effect of Anvillea radiata and to test the storage efficiency of soft wheat by coating. Phytochemical screening conducted on the Anvillea radiata extracts revealed the presence of the elements has known medical and physiological activities. Our results show a correlation between the plant part, extract concentrations and mold species. In g...
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ANTI-BACTERIAL AND TOXICOLOGICAL ACTIVITY IN SILICO OF CINNAMOMUM CASSIA ESSENTIAL OIL
The search for natural anti-microbials present in plants has been the target of intense scientific studies over the last years. The objective of this study was to assess the in-vitro antibacterial potential and in silico toxicology of the essential oil of Cinnamomum cassia (Chinese cinnamon) against E. coli and S. aureus strains. The essential oil was initially solubilized in tween 80 and dimethyl...
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EFFECTS OF NON-CALORIC ARTIFICIAL SWEETENERS (NAS) ON GLYCAEMIC STATUS IN MALE SWISS ALBINO MICE
Objective: The objective of the study was to estimate the effects of Non-caloric Artificial Sweeteners (NAS) on glycaemic status in male Swiss albino mice. Methods: 36 male Swiss albino mice were selected and divided into six groups of 6 animals each. Group 1 served as control and received a normal pellet diet with drinking water. Groups 2, 3, 4, 5 and 6 received normal pellet diet and drinking wa...
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SECONDARY METABOLITES AS LEAD MOLECULES FOR ANTICANCER THERAPIES: A REVIEW
Cancer initiates from the transformation of normal living cells into malignant cells via a multistage event that usually advances from a pre-cancerous phase to a malignant tumour. Anti-metastatic drugs or anti-neoplastic drugs prevent and regulate the growth of onco cells. Based on the mode of drugs, the universally anticancer drugs market is categorized into cytotoxic, targeted, and hormonal drug...
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THE PHARMACOLOGICAL ACTIONS OF IRIFLOPHENONE-3-C-β-D GLUCOSIDE: AN OVER VIEW
Iriflophenone 3-C-β-D glucoside is a Benzophenone derivative which can be obtained from various plant sources like Aquilaria crassna, A. sinensis, A. malaccensis, Cyclopia genistoides, Mangifera indica, Dryopteris ramosa etc. It can act as an important herbal active constituent as it has various pharmacological actions, such as Antidiabetic, anti-inflammatory, antioxidant, and antimicrobial agent...
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FORMULATION & EVALUATION OF HERBAL TRANSDERMAL PATCH OF CENTELLA ASIATICA & LIQUORICE TO STUDY WOUND HEALING ACTIVITY
Wound healing remains a significant challenge in modern medicine, necessitating the exploration of innovative therapeutic strategies. Centella asiatica, a widely recognized medicinal herb, has garnered attention for its potential wound healing properties. This study aimed to investigate the efficacy of a Centella asiatica transdermal patch in promoting wound healing. These results suggest that the...
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ANTINOCICEPTIVE AND ANTI-INFLAMMATORY ACTIVITIES OF THE AQUEOUS EXTRACT OF MIKANIA LINDLEYANA IN RODENTS
Mikania lindleyana is a plant widely distributed in Brazilian Amazonia, popularly known as “sucuriju” and largely used in folk medicine to treat inflammation, chronic ulcers and pain. In the present study, we identified the secondary metabolites of the aqueous extract of M. lindleyana (AEML) and investigate its effects on several models of inflammation and nociception in rodents. Phytochemical...
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EFFECT OF COMBINED EXPOSURE OF DICHLORVOS AND MONOCROTOPHOS ON NEUROTRANSMITTERS AND ACETYLCHOLINESTERASE IN RAT
Organophosphate pesticides are associated with neurotoxicity. Organophosphates are cholinesterase-inhibiting chemicals used predominately as pesticides. These have played a very important role in sustainable production of food, animal feed and as protection against disease vectors. They are also used as chemical warfare agents (nerve agents). The effects of dichlorvos and monocrotophos on brain ne...
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