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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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35.

RELATIVE STRUCTURAL ANALYSIS OF LytTR DOMAIN OF AgrA PROTEIN INVOLVED IN BACTERIAL QUORUM SENSING

Resistance to antimicrobials by pathogenic bacteria is a global menace. An attractive pathway to resolve this problem of resistance may be achieved by targeting the bacterial quorum sensing (QS) process. Fighting bacterial infections by interfering with their command language and disrupting virulence expression could serve as a viable alternative. One of the current strategies is to attenuate viru...

H. K. Basak, A. Chatterjee and A. Pal *

Microbiology & Computational Biology Laboratory, Department of Botany, Raiganj University, Raiganj, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.11(6).2828-39

2828-2839

2293

1209

48.

PHYTOCHEMICAL INVESTIGATION, ISOLATION AND CHARACTERIZATION OF BETULIN FROM LEAF OF GYMNOSPORIA MONTANA

Ethnomedicinal plant-like Gymnosporia montana belonging to the family Celastraceae is commonly known as Vikalo in Gujarat. Ethanomedicinally, fresh leaves of Vikalo are chewed in trible regions of Gujarat to cure jaundice. Phytochemical screening of the plant showed the presence of phytoconstituents like phenol, flavonoids, alkaloids, triterpenoids, and saponin. The present study was undertaken fo...

D. Bhavita *, B. Lakshmi and M. Zaveri

K. B. Institute of Pharmaceutical Education and Research, Gandhinagar, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.12(3).1752-56

1752-1756

2293

1323

14.

DESIGN AND EVALUATION OF CHRONOTHERAPEUTIC ANTI-HYPERTENSIVE COMBINATION THERAPY USING MINI-TABLETS TECHNOLOGY

Hypertension or elevated blood pressure (BP) is a serious medical condition that significantly increases the risks of heart, kidney, brain, and other diseases. In persons with normal BP and uncomplicated essential hypertension, BP falls to the lowest levels during the nighttime sleep, and rises suddenly with morning awakening, and reaches the peak during the initial h of diurnal activity. The opti...

M. A. Hadi *, T. B. Balla, R. Unissa and A. Patel

School of Pharmacy, College of Health Sciences and Medicine, Wolaita Sodo University, Ethiopia.

DOI: 10.13040/IJPSR.0975-8232.12(8).4185-96

4185-4196

2293

1161

14.

A COMPREHENSIVE REVIEW ON PSIDIUM GUAJAVA LINN: AS AN HERBAL REMEDY

Psidium guajava Linn is an herbal remedy used in Ayurveda as a traditional system of medicine in ethnomedicine. It is a tropical evergreen plant that grows in tropical and subtropical climates. It has a wide variety of nutritional components. The whole plant and various parts of the plants possess different types of therapeutic activity, such as Tannin, phenols, triterpenes, flavonoids, essential ...

Saheli Chakraborty, Rajesh Ghosh, Soumyadip Ghosh * and Debgopal Ganguly

Bengal School of Technology, Sugandha, Chuchura, Hooghly - 712102, West Bengal, India

DOI: 10.13040/IJPSR.0975-8232.13(11).4447-54

4447-4454

2293

1064

50.

TOPICAL DRUG DELIVERY OF KETOCONAZOLE ENTRAPPED TRANSFEROSOMAL GEL WITH DESIGN AND ENACTMENT

In pharmaceutical research, the transdermal route of drug delivery has gained great interest, Trasferosomes is a novel vesicular drug carrier system that is composed of water, surfactant, and phospholipids; these were introduced in the early 1990s. The mechanism on which drugs absorb through skin is “osmotic gradient”. Transferosomes, when applied on the skin surface it diffuses into skin laye...

Lovely Chaurasia *, Anuj Pradhania, Sakshi Garg and Gargi Gupta

IIMT College of Medical Sciences, Meerut, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.12(12).6615-21

6615-6621

2292

1365

39.

EVALUATION OF MYCOPLASMA HOMINIS PROTEOME TO IDENTIFY THE POTENTIAL VACCINE CANDIDATE PROTEINS

Objective: Mycoplasma hominisis a gram-negative bacteria belonging to class Mollicutes that is commonly present in men and women of reproductive age. At present, there is no effective prophylaxis for Mycoplasma hominis, as it has gained resistance for the drugs hence an in-silico approach was undertaken to find out the peptide-based vaccine for the pathogen. Methods: In women, it affects the genit...

S. Madagi and S. Shiragannavar *

Department of Studies and Research in Bioinformatics, Karnataka State Akkamahadevi Women’s University Vijayapura, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.11(4).1831-36

1831-1836

2291

1246

21.

TO STUDY THE ANTI-INFLAMMATORY PROPERTIES OF AQUEOUS EXTRACT OF LEAVES OF IMPATIENS BALSAMINA IN EXPERIMENTAL ANIMAL MODELS

The present study was undertaken to study the anti-inflammatory effects of aqueous extract of Impatiens balsamina leaves in suitable animal models. The leaves of Impatiens balsamina were extracted with distilled water using the Soxhlet apparatus. The extract thus obtained was screened for anti-inflammatory activity using Cotton pellet implantation method, Granuloma pouch method, and formaldehyde a...

Debashree Ningthoujam * and Aruna Soibam

Department of Pharmacology, Imphal, Manipur, India.

DOI: 10.13040/IJPSR.0975-8232.13(5).2039-47

2039-2047

2289

1174

26.

IN-VITRO SEED GERMINATION AND EFFECT OF TDZ AND AgNO3 ON HIGH FRE-QUENCY SHOOT REGENERATION FROM RUELLIA TUBEROSA L., USING COTYLE-DANARY NODE EXPLANTS

Ruellia tuberosa, commonly called Minnie root, has plenty of applications in herbal medicine due to the presence of several bioactive compounds. A simple, efficient, and reproducible in-vitro plant regeneration protocol was developed for Ruellia tuberosa. The cotyledonary nodal explants were excised from seedlings were inoculated on Murashige and Skoog (MS) medium supplemented with various concent...

P. V. C. Lakshmi, C. M. N. Reddy, P. Rathinapriya, M. Ramesh and B. Srinivas *

Department of Biotechnology, Dravidian University, Kuppam, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.12(4).2211-24

2211-2224

2288

1366

50.

PLANT MEDIATED GREEN SYNTHESIS OF SILVER NANOPARTICLES USING RUMEX OBTUSIFOLIUS LEAF EXTRACT AND THEIR ANTIBACTERIAL ACTIVITY

Rumex obtusifolius, belonging to the Polygonaceae family, commonly known as ‘broad-leaf-dock’ is one of the most important medicinal plants. It is common wayside weeds and uses as an antidote to nettle, depurative, astringent, laxative, and tonic and in the treatment of sores, blisters, jaundice, burns, cancer, and tumors. In this study, we design to synthesize silver nanoparticles from silver...

M. C. Purohit, M. Singh *, G. Kumar and N. Singh

Department of Chemistry, B. G. R. Campus Pauri (H.N.B. Garhwal University (A Central University), Srinagar, Garhwal, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.11(9).4524-29

4524-4529

2287

1114

29.

IN-VITRO ANTIBACTERIAL ACTIVITIES OF EXTRACTS OF YEMENI PLANTS MYRTUS COMMUNIS L. AND FLEMINGIA GRAHAMIANA WIGHT & ARN.

Yemen is located on the southwestern brink of the Arabian Peninsula. The methanolic and aqueous crude extracts of two Yemeni traditional medicinal plants Myrtus communis L. and Flemingia grahamiana Wight & Arn were evaluated for antibacterial activity in-vitro by Well- diffusion method against six bacterial pathogens, Staphylococcus aureus, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella...

L. N. A. Abdulqawi * and S. A. Quadri

Department of Zoology, Maulana Azad College, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.12(2).956-62

956-962

2287

1246