Pages Menu
TwitterRssFacebookWhatsapplinkedin
ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

Categories Menu

Most Popular

 
Title
Views
PDF
Cited
25.

FORMULATION EVALUATION AND OPTIMIZATION OF METFORMIN HCl MATRIX TABLET USING NATURAL POLYMER

Objectives: The main objective was to find out a suitable and effective natural release retardant, which can be used in matrix tablet preparation along with synthetic excipients. Methods: Tamarind seed polysaccharides (TSP) were isolated from Tamarindus indica by hot extraction method followed by freeze-drying and yield was found to be 16.85%. Microbial studies confirmed that TSP doesn’t support...

T. Saikia

Girijananda Chowdhury Institute of Pharmaceutical Science, Azara, Guwahati, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.10(12).5435-42

5435-5442

4269

1445

13.

ANTIMICROBIAL, CYTOTOXICITY, FREE RADICAL SCAVENGING ACTIVITIES AND COMPOUNDS ISOLATED FROM THE ROOTS OF HEMIDESMUS INDICUS (LINN.) R. BR.

Hemidesmus indicus Linn. R. Br. is a twining shrub traditionally used for the treatment of various diseases and ailments in the rural area of Bangladesh.  Different extracts (methanol, hexane, ethyl acetate, n-butanol and water) from the roots of this shrub tested for their antimicrobial, cytotoxicity and free radical scavenging activities. All extracts showed moderate free radical scavenging act...

A. Saha, J. Tasnim , S. Ahmed , T. Muslim , M. A. Rahman and N. Sultana *

Principal Scientific Officer Institute of National Analytical Research and Service (INARS), BCSIR Laboratories Dhaka, Dr. Qudrat-i-Khuda Road, Dhanmondi, Dhaka-1205, Bangladesh.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(1).117-22

117-122

4268

2277

26.

OPTIMIZATION OF ULTRASOUND-ASSISTED EXTRACTION OF TOTAL FLAVONOIDS AND ANTIOXIDANT PROPERTIES FROM TRIGONELLA FOENUM-GRAECUM SEEDS WITH RESPONSE SURFACE METHODOLOGY

Trigonella foenum-graecum is an annual plant in the family Fabaceae. The distinctive cuboid-shaped, yellow to amber coloured fenugreek seeds are frequently encountered in the cuisines of the Indian subcontinent. In this study, Trigonella foenum-graecum is used as an experimental matrix. Ultrasound-assisted extraction (UAE) of total flavonoids from Trigonella foenum-graecum is studied with dua...

Shaileyee Das

Department of Pharmaceutical Chemistry, NSHM College of Pharmaceutical Technology, NSHM Knowledge Campus Kolkata group of Institution, Kolkata-700053, West Bengal, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(11).4308-18

4308-4318

4268

1750

18.

EVALUATION OF IN VITRO ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF CASSIA AURICULATA LINN. EXTRACTS

Objective: To evaluate in vitro antioxidant and anti-inflammatory activity of Cassia auriculata leaf extracts. Methods: Herbal extraction was done by Soxhlet extraction method with increasing polarity of Solvents viz., Chloroform, Ethanol, Methanol. Phytochemicals analysis was done using different biochemical tests. Antioxidant potential of plant extracts were analyzed by ferric ion reducing antio...

J. B. Uppin, V. M. Chandrasekhar and G. R. Naik*

Department of Studies in Biotechnology, Gulbarga University, Gulburga, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.9(2).575-81

575-581

4268

1782

13.

COMPARATIVE MOLECULAR DOCKING STUDIES AND STRUCTURAL PREDICTION OF PLANT COMPOUNDS ON LRRK2

Neurodegenerative disease is the condition of brain cells that lose of its ability to generate the neurotransmitters and this leads to the accumulation of proteins in the brain. These condition causes memory loss and problems in the cognitive functions. Neurological diseases are characterized by four major types such as Alzheimer’s disease, Parkinson’s disease, Huntington disease, Amyotrophic ...

P. Jayanthi * and K. Vijayalakshmi

Department of Biochemistry, Bharathi Women’s College, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.9(6).2258-65

2258-2265

4268

1820

7.

ESTIMATION OF OFLOXACIN IN BULK AND TABLET DOSAGE FORM BY NANODROP SPECTROPHOTOMETRIC METHOD

Ofloxacin is a fluoroquinolone antibiotic considered to be a second-generation fluoroquinolone. Ofloxacin is administered by oral, intravenous or topical (eye and ear drop) route. It is used as antibacterial for the treatment of various diseases like chronic bronchitis, pneumonia, urethritis, cervicitis, urinary tract infections, prostatitis, uncomplicated urethral and cervical gonorrhea. Ofloxaci...

Rakesh K. Singh*, Pankaj S. Patel, Darshika Awasthi ,Bipin Bihari and Prabodh Shukla

College of Pharmaceutical Sciences *, Mohuda, Berhampur (Orissa), India

DOI: 10.13040/IJPSR.0975-8232.1(4).73-79

73-79

4267

1583

38.

PHARMACOPHORE MAPPING AND VIRTUAL SCREENING ON HUMAN ALPHA AMYLASE INHIBITORS

Diabetes is a non communicable chronic metabolic disease characterized by high blood glucose level in the body. Targeting alpha amylase to control diabetes has long been studied. This study focused on developing pharmacophore model for set of inhibitor that possess anti amylase activity based on previous studies. Developing a pharmacophore model for these compound yields a hypothesis of ADDRR.  F...

S. Santhosh

Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur - 613401, India.

DOI: 10.13040/IJPSR.0975-8232.6(5).2127-32

2127-32

4267

2114

7.

PHYTOCHEMICAL SCREENING, IN-VITRO MEMBRANE STABILIZING AND THROMBO-LYTIC ACTIVITIES OF LOPHOPETALUM JAVANICUM

In the present study, different extracts of Lophopetalum javanicum (Zoll) leaves were evaluated for erythrocyte membrane stabilizing and thrombolytic activities. Phytochemical analysis of the plant was also performed to detect presence of different kinds of phytoconstituents. In order to predict anti-inflammatory activity the plant extracts were subjected to check erythrocyte membrane stabilizatio...

Md. Reyad-ul-Ferdous, Md. Golam Azam* and Md. Delower Hossain

Department of Pharmacy, North South University, Dhaka-1229, Bangladesh

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(2).350-53

350-353

4266

1781

12.

DEVELOPMENT AND VALIDATION OF A HPLC METHOD FOR IN-VIVO STUDY OF DICLOFENAC POTASSIUM

A High Performance Liquid Chromatographic method was developed for determination of Diclofenac Potassium in in-vivo study during bioavailability study. The chromatographic separation was conducted on Shimadzu Prominence LC 20 connected with PDA detector; using mixed column ODS/Cyano; ACE, (100 x 4.6 mm, 5 µm). The mobile phase was isocratic consisted of Methanol: 50 mM potassium dihydrogen phosph...

Mohamed Aly Abd El Aziz Aly El Degwy*, Mohamed Aly Mahmoud Aly and Mamdouh Salah El Den

Mepaco Pharmaceutical Company, 141 Street Ahmed Zaki, Maadi, Cairo, Egypt

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(2).622-27

622-627

4266

1561

34.

ISOLATION AND DEVELOPMENT OF AN HPLC METHOD FOR THE QUANTIFICATION OF A BIOMARKER IN THE ROOTS OF PAULLINIA PINNATA

An RP-HPLC method to be used to quantitate the amount of a biomarker in the roots of Paullinia pinnata was developed. The root bark was milled and extracted and the dry powder obtained taken through column chromatography (CC). The biomarker was then isolated. The melting point of the biomarker was determined and found to be 117-119 oC. A RP-HPLC method was successfully developed and used to quanti...

E. K. Cudjoe , John N. A. Addotey *, Nathaniel N. A. Okine , Reimmel K. Adosraku, Kofi Annan

Department of Pharmaceutical Chemistry *, KNUST, Kumasi, Ghana. KNUST, Kumasi, Ghana.

DOI: 10.13040/IJPSR.0975-8232.7(8).3446-52

3446-52

4265

1635