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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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4.

HISTORY, MANIFESTATION AND PREVENTIVE MEASURES FOR RUBELLA IN INDIA: A REVIEW

Rubella is an eradicable illness on the grounds of immunization against it produces solid protection. The name rubella comes from the Latin language, and it means “little red”. In olden times people thought that rubella was a variant of measles. German literature first described it as a separate disease, and hence it was also called “German Measles”. People are the main reservoir of the in...

D. C. Sati and R. K. K. Arya *

Department of Pharmaceutical Sciences, Kumaun University, Nainital, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.10(11).4844-52

4844-4852

4293

1569

14.

PHYSICAL-CHEMICAL CHARACTERIZATION, ANATOMICAL AND SEASONAL EVALUATION OF THUJA OCCIDENTALIS L. (CUPRESSACEAE)

Thuja occidentalis L. is a plant widely used therapeutically. Having seen the necessity to standardize the vegetal drug and to evaluate the interference of certain environmental and seasonal factors on the synthesis of metabolites, notably flavonoids, this work considered anatomical and physical-chemical characterization assays for the aforesaid vegetal drug, in addition to phytochemical prospecti...

C.B.M. Figueirêdo , L.D.S. Alves , C.C.A.R. Silva , P.A. Ferreira , G.S. Marques , A.S.C.O. Santana , K.P. Randau , R.M.M. Pimentel , R.M.F. Silva and P.J. Rolim-Neto*

Department of Pharmaceutical Sciences, Federal University of Pernambuco, Brazil.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(5).1721-31

1721-1731

4292

2480

27.

FORMULATION OF DIRECT COMPRESSED VERAMPAMIL SUSTAINED RELEASE FORMULATION USING OPTIMIZED CO PROCESSED EXCIPIENTS

Pharmaceutical excipients when co-processed have improved flow and disintegrant properties in tablet formulations. However, physical mixtures of excipients show limited functions, poor flow properties, and poor functional properties so they cannot be used directly in tablet formulations. Majority of solid dosage forms contain multiple excipients, which provides a wide window of opportunities by co...

P. Preetha*, A. Srinivasa Rao and C. Y. Priyanka

Department of Pharmaceutics, Bhaskar Pharmacy College, Hyderabad, Andhra Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.6(10).4324-35

4324-35

4291

1991

52.

EVALUATION OF ANTI-NOCICEPTIVE AND ANTI-PYRETIC ACTIVITY OF AERVA PSEUDOTOMENTOSA LEAVES AQUEOUS EXTRACT

Aerva pseudotomentosa Blatt. & Hallb. (Amaranthaceae) is arid region plant commonly known as Bui. It is used in ethno medicinal practices for the treatment of pain and inflammatory hyperalgesic disorders such as rheumatic pain, fever, inflammation, wounds and urinary disorders. This study was conducted to evaluate the anti-nociceptive, antipyretic effects of A. pseudotomentosa leaves aqueous e...

Abhishek Pandey * and Atul Kaushik

School of Studies in Pharmaceutical Sciences, Jiwaji University, Gwalior, Madhya Pradesh, India. Department of Pharmaceutical Sciences , IFTM University, Moradabad, Uttar Pradesh, India. IPS College of Pharmacy , Gwalior, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.7(11).4686-92

4686-92

4291

1583

27.

NOVEL SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 3-AMINO PHENYL-5-METHYL PYRAZOLES AND ITS DERIVATIVES

Pyrazoles and fused heterocyclic pyrazoles derivatives constitute an interesting class of heterocyclic compounds due to their synthetic versatility and effective biological activity in the field of pharmaceutical science, agriculture etc.  In the present study, new substituted pyrazoles were prepared by condensation of substituted primary amine and ethyl acetoacetate at 1400C to form analides as ...

Priti Warbhe and Reshal Deshmukh*

Department of Chemistry, Shri Shivaji Science College, Congress Nagar, Nagpur, M.S., India

DOI: 10.13040/IJPSR.0975-8232.8(1).217-21

217-221

4291

1822

35.

SENSITIVE, HIGH-THROUGHPUT AND ENANTIOSELECTIVE QUANTITATION OF ZOPICLONE IN HUMAN PLASMA BY LCMS/MS: APPLICATION TO A HUMAN PHARMACOKINETIC STUDY

Zopiclone (ZPC), a cyclopyrrolone derivative, is a short-acting hypnotic agent. Its pharmacological properties include hypnotic, sedative, anxiolytic, anticonvulsant and muscle-relaxant actions. ZPC has a single chiral centre, and its enantiomers are S-zopiclone (S-ZPC) and R-zopiclone (R-ZPC). S-ZPC was adjudge to possess two- fold enhanced pharmacological activity than racemate (ZPC) while its o...

Aslam Khan*, M. Rajput, A. Sen, P. Sinha Ray, S. Biswas, A. Khan and A. More

Clinical Research Services, Reliance Life Sciences Private Limited, Dhirubhai Ambani Life Sciences Centre (DALC), Thane-Belapur Road, Rabale, Navi Mumbai-400 701, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1381-94

1381-1394

4290

3006

12.

ANATOMICAL CHARACTERIZATION AND MICROCHEMISTRY OF VISMIA GUIANENSIS (AUBL.) CHOISY (CLUSIACEAE) BLADE LEAF

Vismia guianensis (Aubl.) Choisy is a tree that belongs to the secondary vegetation in rainforests. This study aimed to perform anatomy analysis by light microscopy; scanning and microchemistry of the leaves of V. guianensis. Tri stratified upper epidermis with intense cutinization and unistratified inferior epidermis was observed. The stomata found are paracytic and the trichomes arranged in rose...

Sarah Regina Pereira Camelo , Russany Silva Costa , Janaina Gell de Pontes Vieira , Roseane Maria Ribeiro-Costa , Wagner Luiz Ramos Barbosa , Flavio Vasconcelos , Jose Otavio Carrera Silva Junior*

Adj. Prof., Laboratory of Pharmaceutical Technology, School of Pharmacy, Institute of Health Sciences, Federal University of Para, University City “Jose da Silveira Netto”, CEP 66075-110, Belem, Para, Brazil

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(5).1312-17

1312-1317

4290

1559

29.

CHOLESTEROL ESTERASE ENZYME INHIBITORY AND ANTIOXIDANT ACTIVITIES OF LEAVES OF CAMELLIA SINENSIS (L.) KUNTZE. USING IN VITRO MODELS

The present study was to evaluate the in vitro cholesterol esterase enzyme inhibitory and in vitro antioxidant activity of the methanol extract of the leaves of Camellia sinensis (L.).  Phytochemical screening of the extract shows the presence of flavonoids, phenolics and terpenoids. The extract shows ability to inhibit the enzyme with IC50 (82.46±0.74µg/ml) whereas that of standard, Orlistat (...

A. Pradeep Kumar*, A. T. Sivashanmugam M. Umamaheswari, V. Subhadradevi and P. Jagannath

Department of Pharmacology, College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences, 395, Sarojini Naidu Road, Siddhapudur, Coimbatore-641044, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(10).2675-80

2675-2680

4290

2129

21.

SYNTHESIS AND EVALUATION OF MESOPOROUS SILICA NANOPARTICLES (MSN) LOADED COX-II INHIBITOR – MELOXICAM FOR TARGETED COLORECTAL CANCER TREATMENT

Polymer functionalised mesoporous silica nanoparticles hold great promise to enhance drug targeting and cell internalisation for cancer cells. Since the presence of abundant folate receptors on cancer cells, folic acid functionalised mesoporous silica nanoparticles (MSN) were used as folate marker and polyethyleneimine was used to improve cell internalisation. Meloxicam was loaded into the pores o...

D. Kaduskar* and R. Yawalkar

Department of Pharmaceutics, Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM’s, NMIMS, Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.8(10).4230-38

4230-4238

4290

1743

2.

ACRIDINE A VERSATILE HETEROCYCLIC MOIETY AS ANTICANCER AGENT

Acridine is a heterocyclic nucleus consisting of three fused rings heterocyclic moiety and a presence of Nitrogen in the ring structure. It is used in a large number of therapeutically agents for curing ailments like antimalarial, antiseptics, abortifacient, anticancer, and so on because of its adjuvant molecule attached to it. It possesses high pharmacological properties mainly with respect to ca...

N. B. Panchal *, P. H. Patel, N. M. Chhipa and R. S. Parmar

Parul Institute of Pharmacy and Research, Parul University, Waghodia, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.11(10).4739-48

4739-4748

4290

2540