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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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24.

ALLIUM SATIVUM REGULATES LIPID METABOLISM IN ALLOXAN INDUCED DIABETIC RATS

Allium sativum (A. sativum), commonly known as garlic, is a species in the onion genus, Allium. The hypolipidemic activity of A. Sativum (Family: Amaryllidaceae) extract have been studied in alloxan-induced diabetic rats. In this model oral administration of extract (500mg/kg bw., p.o.) for 15 days in diabetic-dyslipidemic rats exerted significant lipid lowering effect as assessed by the reversal ...

Prabha Verma *, Brijesh Rathore, Vishnu Kumar, Abbas Ali Mahdi and Raj Kumar Singh

Department of Biochemistry, Maharani Laxmi Bai Medical College, Jhansi,Uttar Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.7(12).4949-55

4949-4955

4136

2325

3.

VASORELAXANT AND ANTIHYPERTENSIVE EFFECTS OF RHUS PENTAPHYLLA (SEARSIA PENTAPHYLLA)

Rhus pentaphylla (Jacq.) Desf. (Searsia pentaphylla (Jacq.) FA. Barkley) is used for its colorant and tanning properties by the local population. The bark, leaves, roots, and fruits are employed in Moroccan traditional medicine to treat gastrointestinal disorders and diarrhea. Nevertheless, the pharmacological properties of R. pentaphylla on cardiovascular diseases have not yet been presented. Thi...

N. Messaoudi, H. Mekhfi, M. Aziz, A. Legssyer, M. Bnouham and A. Ziyyat *

Laboratory of Physiology, Genetics and Ethnopharmacology, Department of Biology, Faculty of Sciences, University Mohammed First, Oujda-Morocco.

DOI: 10.13040/IJPSR.0975-8232.10(10).4430-43

4430-4443

4136

1890

34.

ANTIMICROBIAL ACTIVITY OF EUGENOL AGAINST HUMAN PATHOGENIC BACTERIA BY MINIMAL INHIBITORY CONCENTRATION, MINIMAL BACTERICIDAL CONCENTRATION AND DISC-DIFFUSION METHODS

Essential oils from plants have been reported to have antibacterial activity. Essential oil is a mixture of many chemicals, and one or more chemicals in essential oil may have antibacterial activity. In our laboratory, essential oil from the leaves of Ocimum sanctum L. was found to have antibacterial activity against 18 human bacteria. GC-MS analysis of the Ocimum sanctum essential oil revealed th...

V. Jayapal

Mahatma Gandhi Medical College & Research Institute, Pillaiyar Kuppam, Puducherry, India.

DOI: 10.13040/IJPSR.0975-8232.12(1).330-35

330-335

4136

1642

30.

COMPARATIVE STUDY OF AZADIRACHTA INDICA LEAF POWDER AND ITS DIFFERENT EXTRACTS ON GLYCEMIC, INSULINEMIC AND LIPIDEMIC STATUS OF TYPE 2 DIABETIC MODEL RATS

The present study was carried out to investigate the effect of oral feeding of A. indica leaf (powder, aqueous and 80% ethanol extract) in STZ induced type 2 diabetic rats. Diabetes was induced by single intraperitoneal injection of STZ to 48hrs old pups and experiments were carried out three months later. For chronic experiment type 2 rats were divided into 5 groups: 1) Water control, 2) Glibencl...

M. A. Morshed , N. Fayzunnessa , M. A. Haque , A. Uddin , A. Bhoumik , L. Ali and B. Rokeya

Department of Pharmacy, North South University , Bashundhara, Dhaka, Bangladesh

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(4).954-60

954-960

4135

1689

37.

A COMPARISON BETWEEN WELLS’ SCORE AND MODIFIED DOPPLER ULTRASOUND IN THE DIAGNOSIS OF DEEP VENOUS THROMBOSIS OF THE LOWER LIMB

The assessment of the probability of occurrence of deep vein thrombosis played a very important part in making a correct diagnosis and modified Wells’ score is a widely used prediction rule for pre-test probability assessment. We aimed to evaluate the diagnostic accuracy of the modified Wells’ score in the diagnosis of lower extremity deep vein thrombosis compared to Doppler ultrasound study. ...

M. K. A. Razak *, J. I. Rasheed and A. A. Hamad

Department of Medicine, The University of Baghdad, Baghdad College of Medicine, Baghdad, Iraq.

DOI: 10.13040/IJPSR.0975-8232.10(5).2369-74

2369-2374

4135

1346

15.

PHARMACOGNOSTIC STUDIES ON LEAF AND STEM OF CRESSA CRETICA LINN.

Cressa cretica is halophytic plant belongs to family Convolvulaceae, growing extensively all over India. The entire plant is medicinally important and used extensively in traditional system of medicine. The present work attempted to summarize the macroscopic characters of the plant Cressa cretica. The microscopic characters, physical constant values, extractive values, fluorescent analysis of the ...

P. Sunita*, S. Jha and S. P. Pattanayak

Government Pharmacy Institute, Govt. of Jharkhand, Ranchi, Jharkhand, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(4).849-55

849-855

4134

1750

68.

ASSESSMENT OF SURGICAL STRESS RESPONSE AND PREDICTING ITS FUNCTIONAL IMPLICATIONS

Surgery alters the homeostatic balance and defence mechanisms in body eliciting certain responses called as stress response. In addition certain peri-operative factors may also influence the degree of stress response reflecting surgical recovery. The present study is an attempt to assess surgical stress response and to determine the influence of peri-operative factors on it. This study investigate...

M. J. Sravanthi *, V. S. Ranjani, S. K. K. Zia, S. V. Guru and P. G. Reddy

Department of Pharmacy Practice, P. Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(11).5009-14

5009-5014

4134

1920

15.

PREPARATION AND PROPERTIES OF MACROCYCLIC LIGAND AND ITS COMPLEXES DERIVED FROM TRIMETHOPRIM AND DIETHYL PHTHALATE

Macrocyclic complexes of  MnII, CoII, NiII and CuII   using a macrocyclic ligand derived by the condensation of Trimethoprim and diethyl phthalate have been prepared and characterized by electronic, IR and NMR spectral studies as well as magnetic moment and conductivity. On the basis of spectral studies, an octahedral geometry has been proposed for all the complexes....

M. Amaladasan and P. Victor Arockiadoss*

Postgraduate and Research Department of Chemistry, St. Joseph’s college (Autonomous), Tiruchirappalli-620002, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(5).1327-30

1327-1330

4132

1777

15.

ISOLATION AND EVALUATION OF CASSIA AUNGOSTIFOLIA SEED MUCILAGE AS GRANULATING AGENT

Cassia aungostifolia is a common herbaceous belongs to the family of Caesalpiniaceae. Seeds of plant contain gluco-mannose hence attempt to evaluate the seeds for suitability as tablet binder is considered and the present exploration repots the isolation of mucilage of Cassia aungostifolia seed. The DSC and FTIR thermograms of drug and mucilage indicated no chemical interaction. Phytochemical and ...

Sudarshan Singh* and SangeetaSingh

Shree HNS Institute of Pharmaceutical Education and Research, Rajkot, (Gujarat), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(8-S).118-25

118-125

4131

1525

21.

QUANTIFICATION OF A CRUDE EXTRACT FROM HEDERA COLCHICA

Crude extract from the leaves of Hedera colchica (C. Koch) C. Koch proved to have an antiulcer activity in pharmacological experiences. Hederacolchisid F (HCF) is being the chemical marker of this plant, a simple and reliable HPLC method is developed for the quan­ti­ta­ti­ve evaluation of the extract using this compound. The chromatographic separation was achieved using an Eclipse XDB-Phenyl c...

Malkhaz Getia *, Vakhtang Mshvildadze, Genri Dekanosidze and André Pichette

Tbilisi State Medical University’s Iovel Kutateladze Institute of Pharmacochemistry , Laboratory of Terpenic Compounds, 36 P. Sarajishvili, Tbilisi, Georgia

DOI: 10.13040/IJPSR.0975-8232.6(9).3836-40

3836-40

4131

2031