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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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30.

COMPARATIVE STUDY OF AZADIRACHTA INDICA LEAF POWDER AND ITS DIFFERENT EXTRACTS ON GLYCEMIC, INSULINEMIC AND LIPIDEMIC STATUS OF TYPE 2 DIABETIC MODEL RATS

The present study was carried out to investigate the effect of oral feeding of A. indica leaf (powder, aqueous and 80% ethanol extract) in STZ induced type 2 diabetic rats. Diabetes was induced by single intraperitoneal injection of STZ to 48hrs old pups and experiments were carried out three months later. For chronic experiment type 2 rats were divided into 5 groups: 1) Water control, 2) Glibencl...

M. A. Morshed , N. Fayzunnessa , M. A. Haque , A. Uddin , A. Bhoumik , L. Ali and B. Rokeya

Department of Pharmacy, North South University , Bashundhara, Dhaka, Bangladesh

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(4).954-60

954-960

4081

1667

88.

SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS ESTIMATION OF CEFUROXIME SODIUM AND SULBACTAM SODIUM IN INJECTON

Cefuroxime is a 2nd-generation cephalosporin and Sulbactam is a β-Lactamase inhibitor. The combination formulation is used for the treatment of lower respiratory tract infection. Two new, simple, accurate and precise UV spectrophotometric methods have been developed and validated for the simultaneous determination of Cefuroxime Sodium (CEF) and Sulbactam Sodium (SUL) in their combined dosage form...

F.M. Patel, J. B. Dave and C. N. Patel

Department of Quality Assurance, Shri Sarvajanik Pharmacy College, Mehsana-384001, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3513-17

3513-3517

4081

2825

16.

EFFECT OF CEFTRIAXONE ON ISOLATED GASTROINTESTINAL, TRACHEAL AND UTERINE SMOOTH MUSCLES

The pharmacodynamic effect of ceftriaxone on smooth muscles was investigated in isolated organs. Maximum stimulation of isolated guinea pig's ileum, rabbit's duodenum and rat's fundic strip was achieved by addition of 1024 µg of ceftriaxone/ml bath. While in isolated rat's colon, it was achieved by 512 µg of ceftriaxone/ml bath.  The effect of graded increased concentrations of ceftriaxone on i...

M. G. Elsayed, A. A. Elkomy and M. H. Aboubakr*

Department of Pharmacology, Faculty of Veterinary Medicine, Benha University, Egypt

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(9).2347-51

2347-2351

4081

1481

52.

PREPARATION, CHARACTERIZATION AND IN-VIVO RELEASE OF NANOMEDICINE (SOLID LIPID NANOPARTICLE) ASSOCIATE WITH THE EXTRACT OF PTEROSPERMUM ACERIFOLIUM FOR THE SCREENING OF NEUROBEHAVIOURAL

Advances in nanoparticulate frameworks for enhanced medication conveyance show an extraordinary potential for the organization of urgent dynamic particles. The fundamental motivation behind creating elective medication conveyance advances is to build proficiency of medication conveyance. Pterospermum acerifolium is normal plant in India is viewed as carminative, stimulant and emmenagogue. The poin...

Ankur Choubey *, Shashi Alok , Gopal Garg, Santosh Kumar Singh

Research Scholar, School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur, Rajasthan , India

DOI: 10.13040/IJPSR.0975-8232.7(7).3154-62

3154-62

4081

1430

39.

TOPSIS ANALYSIS FOR THE PREDICTION OF DIABETES BASED ON GENERAL CHARACTERISTICS OF HUMANS

Worldwide diabetic patients are very common. This paper studies spread of diabetes in human living in Lahore, Pakistan. Data is collected from two local hospitals of Lahore and TOPSIS is applied to draw the results of the study. The study points out the people who are more likely to have diabetes due to various parameters like age, weight, height, body mass index (BMI), systolic blood pressure (SB...

M. Zulqarnain, F. Dayan * and M. Saeed

Department of Mathematics, University of Management and Technology, Lahore, Pakistan.

DOI: 10.13040/IJPSR.0975-8232.9(7).2932-39

2932-2939

4081

1446

11.

POLYCYSTIC OVARIAN SYNDROME- A MULTIFACETED DISEASE: A REVIEW

Polycystic ovarian syndrome (PCOS) is one of the most prevalent endocrine disorders in females of reproductive age. Globally, it has been found that PCOS affects 10% of reproductive-age women when using the NIH criteria for diagnosis, and up to 18% of reproductive-age women are diagnosed with PCOS as per the Rotterdam criteria. Mostly symptoms of PCOS include irregular menstrual cycles, signs of h...

M. Maqbool, I. Gani and M. I. Geer

Department of Pharmaceutical Sciences, University of Kashmir, Hazratbal Srinagar, Jammu and Kashmir, India.

DOI: 10.13040/IJPSR.0975-8232.10(3).1072-79

1072-1079

4081

1690

81.

BIOCHEMICAL ESTIMATION OF PRIMARY METABOLITES OF CASSIA NODOSA BUNCH.

Cassia nodosa Bunch.is an ornamental tree belonging to family Leguminosae, popularly known as Pink Shower is a perennial tree. Laboratory evaluations were made to asses the study of primary metabolites in different plant parts of Cassia nodosa Bunch. The highest amount of soluble sugars (10.27mg/ gdw), lipids (32.36mg/gdw), phenols (20.0mg/gdw), DNA (11.78mg/gdw) and Chlorophyll- a+b (0.94mg/gdw) ...

R.A. Sharma, Daulat Singh, Ankita Yadav* and Richa Bhardwaj

Plant Physiology and Biochemistry Lab., Lab. no. 14, Department of Botany, University of Rajasthan, Jaipur-302 004, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3476-80

3476-3480

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39

21.

EVALUATION OF CNS DEPRESSANT AND ANALGESIC ACTIVITIES OF THE METHANOL EXTRACT OF PIPER LONGUM LINN. LEAVES

Present study reports CNS depressant and analgesic activities of methanol extract obtained from the leaves of Piper longum L (MEPL). CNS depressant activity was evaluated by using open field and hole cross tests at doses of 250 and 500 mg/kg body weight while peripheral analgesic activity was evaluated by using acetic acid induced writhing method and formalin test respectively in rat model at 100 ...

Al Mamun , Mst. Hajera Khatun , Md. Rafikul Islam*, Laizuman Nahar , K. M. Shams-Ud-Doha and Farhana Alam Ripa

Lecturer, Department of Pharmacy, International Islamic University Chittagong, Bangladesh

DOI: 2http://dx.doi.org/10.13040/IJPSR.0975-8232.2(11).2874-79

2874-2879

4080

1534

41.

PRODUCTION OF XYLANASE BY PENICILLIUM SP. AND ITS BIOBLEACHING EFFICIENCY IN PAPER AND PULP INDUSTRY

The main objective of this study is to evaluate the ability of production of xylanase by a fungal strain Penicillium sp. isolated from decaying wood. Xylanases are hydrolytic enzymes produced by many microorganisms which catalyze the hydrolysis of xylan polymer to xylose monomer. The xylanase production was carried out under submerged fermentation xylose as the main substrate, and the enzyme yield...

A. Sridevi *, G. Narasimha and P. S. Devi

Department of Applied Microbiology, Sri Padmavati Mahila University, Tirupati, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(3).1307-11

1307-1311

4080

1488

41.

DEVELOPMENT AND VALIDATION FOR HIGH-PERFORMANCE MASS SPECTROMETRY METHOD FOR DETERMINATION OF BALOXAVIR MARBOXIL IN BIOLOGICAL MATRICES

The validated protein precipitation method was applied for the estimation of Baloxavir marboxil in human plasma with Oseltamivir as an internal standard (ISTD) by using HPLC-ESI-MS/MS. The chromatographic separation was achieved with 0.1% formic acid in combination with methanol (25:75 v/v) using the C18 column Ascentis Express (50 mm × 4.6 mm, 2.7 µm). The total analysis time was 3 min and the ...

B. Bhadru *, V. V. Rao and S. Vidyadhara

Acharya Nagarjuna University, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(5).2324-31

2324-2331

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