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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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52.

PREPARATION, CHARACTERIZATION AND IN-VIVO RELEASE OF NANOMEDICINE (SOLID LIPID NANOPARTICLE) ASSOCIATE WITH THE EXTRACT OF PTEROSPERMUM ACERIFOLIUM FOR THE SCREENING OF NEUROBEHAVIOURAL

Advances in nanoparticulate frameworks for enhanced medication conveyance show an extraordinary potential for the organization of urgent dynamic particles. The fundamental motivation behind creating elective medication conveyance advances is to build proficiency of medication conveyance. Pterospermum acerifolium is normal plant in India is viewed as carminative, stimulant and emmenagogue. The poin...

Ankur Choubey *, Shashi Alok , Gopal Garg, Santosh Kumar Singh

Research Scholar, School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur, Rajasthan , India

DOI: 10.13040/IJPSR.0975-8232.7(7).3154-62

3154-62

4078

1429

22.

ANTIOXIDANT ANALYSIS AND ENZYME INHIBITION ASSAY OF PLANTS OF APOCYNACEAE FAMILY FOR ULCERS

Different plants of the Apocynaceae family viz. Alstonia scholaris, Calotropis procera, Rauvolfia serpentine, Hemidesmus indicus and Calotropis gigantean are traditionally being reported in ulcers treatments. The present study was aimed to validate the authenticity of correlationship of various phytoconstituents concentrations, antioxidant activity and urease inhibitory potential of the same. Vari...

N. Sikri and S. Dalal*

Department of Biotechnology, Kurukshetra University, Kurukshetra, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.9(2).608-16

608-616

4078

1654

39.

EVALUATION OF RATIONAL USAGE OF ANTIMICROBIAL AGENTS IN THE PAEDIATRIC DEPARTMENT AT TERTIARY TEACHING CARE HOSPITAL, GUJRAT

Background: Prescription of drugs which needs to be continuously assessed and refined according to disease progression. It not only reflects the physician’s knowledge about drugs but also know the pathophysiology of diseases and attitude towards rational prescribing.  Methods: Retrospective study was carried out by collecting 350 prescriptions containing antimicrobial agents of the indoor patie...

Vipul Prajapati * and J. D. Bhatt

M.B.B.S, M.D (Pharmacology) Assistant professor, Department of pharmacology, AMC MET Medical College, Ahmedabad-380008, Gujrat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(12).5374-81

5374-5381

4077

1506

54.

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF Cu(II), Co(III) AND Fe(III) COMPLEXES OF 2-BENZOYL-3-(NITROPHENYL)QUINOXALINE

A new series of transition metal complexes of the type ML where M = Cu(II), Co(III) and Fe(III) and L = 2-benzoyl-3-(nitrophenyl)quinoxaline have been characterized and the structural features were arrived from the elemental analysis, magnetic susceptibility, molar conductance, FT- IR, UV-Vis and NMR spectral data. From the spectral measurements and magnetic susceptibility values a square planar g...

S. Jone Kirubavathy , R. Velmurugan , K. Parameswari and S. Chitra*

Department of Chemistry, P. S.G. R. Krishnammal College for Women, Coimbatore- 641 004, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2498-04

2508-2517

4077

1735

81.

BIOCHEMICAL ESTIMATION OF PRIMARY METABOLITES OF CASSIA NODOSA BUNCH.

Cassia nodosa Bunch.is an ornamental tree belonging to family Leguminosae, popularly known as Pink Shower is a perennial tree. Laboratory evaluations were made to asses the study of primary metabolites in different plant parts of Cassia nodosa Bunch. The highest amount of soluble sugars (10.27mg/ gdw), lipids (32.36mg/gdw), phenols (20.0mg/gdw), DNA (11.78mg/gdw) and Chlorophyll- a+b (0.94mg/gdw) ...

R.A. Sharma, Daulat Singh, Ankita Yadav* and Richa Bhardwaj

Plant Physiology and Biochemistry Lab., Lab. no. 14, Department of Botany, University of Rajasthan, Jaipur-302 004, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3476-80

3476-3480

4077

39

21.

EVALUATION OF CNS DEPRESSANT AND ANALGESIC ACTIVITIES OF THE METHANOL EXTRACT OF PIPER LONGUM LINN. LEAVES

Present study reports CNS depressant and analgesic activities of methanol extract obtained from the leaves of Piper longum L (MEPL). CNS depressant activity was evaluated by using open field and hole cross tests at doses of 250 and 500 mg/kg body weight while peripheral analgesic activity was evaluated by using acetic acid induced writhing method and formalin test respectively in rat model at 100 ...

Al Mamun , Mst. Hajera Khatun , Md. Rafikul Islam*, Laizuman Nahar , K. M. Shams-Ud-Doha and Farhana Alam Ripa

Lecturer, Department of Pharmacy, International Islamic University Chittagong, Bangladesh

DOI: 2http://dx.doi.org/10.13040/IJPSR.0975-8232.2(11).2874-79

2874-2879

4077

1531

19.

GASTROPROTECTIVE ACTIVITY OF FICUS DALHOUSIAE MIQ. ROOTS ETHANOLIC EXTRACT ON INDOMETHACIN AND COLD RESTRAINT STRESS INDUCED ULCERS IN WISTAR ALBINO RATS

Ficus dalhousiae Miq. is a plant found in Andhra Pradesh and Tamil Nadu on rocky hill top of dry deciduous forests. As it possesses antioxidant property wherein it reduces the elevated levels of ROS, the intent of the present study was to evaluate the Gastro protective effect of Ficus dalhousiae Miq Root ethanolic extract (FDREE) by means of Indomethacin and Cold Restrain stress induced Ulcers in ...

Mohammed Atif *, Mohammed Abdul Muqtadar , Shaik Abdul Rahman , Mohammed Abdul Naser Faisal

11-2-973, Dawood Villa, Bazar Ghat, Nampally Hyderabad 500004

DOI: 10.13040/IJPSR.0975-8232.6(5).1974-81

1974-81

4077

1661

88.

SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS ESTIMATION OF CEFUROXIME SODIUM AND SULBACTAM SODIUM IN INJECTON

Cefuroxime is a 2nd-generation cephalosporin and Sulbactam is a β-Lactamase inhibitor. The combination formulation is used for the treatment of lower respiratory tract infection. Two new, simple, accurate and precise UV spectrophotometric methods have been developed and validated for the simultaneous determination of Cefuroxime Sodium (CEF) and Sulbactam Sodium (SUL) in their combined dosage form...

F.M. Patel, J. B. Dave and C. N. Patel

Department of Quality Assurance, Shri Sarvajanik Pharmacy College, Mehsana-384001, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3513-17

3513-3517

4076

2822

28.

ANTIOXIDANT ACTIVITY OF HONEY SAMPLES FROM THE SOUTHERN RAINFOREST AND NORTHERN SAVANNAH ECOSYSTEMS IN NIGERIA

Selected physicochemical parameters, total phenolics, flavonoids and free radical scavenging activity of honey samples from the northern savannah region and southern rainforest ecosystems of Nigeria were investigated. Moisture and ash content of most samples were within acceptable limits. Total phenolic content ranged from 23.92 to 82.34mgGAE/100g for both ecosystems. Flavonoids varied between 2.5...

Basil Nse Ita

Organic Chemistry Section, Department of Chemistry, University of Uyo, P. M. B 1017 Uyo, Akwa Ibom State, Nigeria

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(8).2115-20

2115-2120

4075

1865

16.

EFFECT OF CEFTRIAXONE ON ISOLATED GASTROINTESTINAL, TRACHEAL AND UTERINE SMOOTH MUSCLES

The pharmacodynamic effect of ceftriaxone on smooth muscles was investigated in isolated organs. Maximum stimulation of isolated guinea pig's ileum, rabbit's duodenum and rat's fundic strip was achieved by addition of 1024 µg of ceftriaxone/ml bath. While in isolated rat's colon, it was achieved by 512 µg of ceftriaxone/ml bath.  The effect of graded increased concentrations of ceftriaxone on i...

M. G. Elsayed, A. A. Elkomy and M. H. Aboubakr*

Department of Pharmacology, Faculty of Veterinary Medicine, Benha University, Egypt

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(9).2347-51

2347-2351

4075

1476