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ROLE OF N-ACETYLCYSTEINE IN RESCUE OF MICE HEART
An imbalance between oxidants and antioxidants generates the oxidative stress. Oxidative stress is the major cause of many diseases like cardiovascular, respiratory disease, renal diseases, neurological diseases, cancer, and aging. Cardiovascular complications are the leading cause of mortality in patients so the purpose of this review is to evaluate the effectiveness of N-acetylcysteine (NAC) in ...
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SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF Cu(II), Co(III) AND Fe(III) COMPLEXES OF 2-BENZOYL-3-(NITROPHENYL)QUINOXALINE
A new series of transition metal complexes of the type ML where M = Cu(II), Co(III) and Fe(III) and L = 2-benzoyl-3-(nitrophenyl)quinoxaline have been characterized and the structural features were arrived from the elemental analysis, magnetic susceptibility, molar conductance, FT- IR, UV-Vis and NMR spectral data. From the spectral measurements and magnetic susceptibility values a square planar g...
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SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS ESTIMATION OF CEFUROXIME SODIUM AND SULBACTAM SODIUM IN INJECTON
Cefuroxime is a 2nd-generation cephalosporin and Sulbactam is a β-Lactamase inhibitor. The combination formulation is used for the treatment of lower respiratory tract infection. Two new, simple, accurate and precise UV spectrophotometric methods have been developed and validated for the simultaneous determination of Cefuroxime Sodium (CEF) and Sulbactam Sodium (SUL) in their combined dosage form...
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POLYCYSTIC OVARIAN SYNDROME- A MULTIFACETED DISEASE: A REVIEW
Polycystic ovarian syndrome (PCOS) is one of the most prevalent endocrine disorders in females of reproductive age. Globally, it has been found that PCOS affects 10% of reproductive-age women when using the NIH criteria for diagnosis, and up to 18% of reproductive-age women are diagnosed with PCOS as per the Rotterdam criteria. Mostly symptoms of PCOS include irregular menstrual cycles, signs of h...
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BIOCHEMICAL ESTIMATION OF PRIMARY METABOLITES OF CASSIA NODOSA BUNCH.
Cassia nodosa Bunch.is an ornamental tree belonging to family Leguminosae, popularly known as Pink Shower is a perennial tree. Laboratory evaluations were made to asses the study of primary metabolites in different plant parts of Cassia nodosa Bunch. The highest amount of soluble sugars (10.27mg/ gdw), lipids (32.36mg/gdw), phenols (20.0mg/gdw), DNA (11.78mg/gdw) and Chlorophyll- a+b (0.94mg/gdw) ...
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EVALUATION OF CNS DEPRESSANT AND ANALGESIC ACTIVITIES OF THE METHANOL EXTRACT OF PIPER LONGUM LINN. LEAVES
Present study reports CNS depressant and analgesic activities of methanol extract obtained from the leaves of Piper longum L (MEPL). CNS depressant activity was evaluated by using open field and hole cross tests at doses of 250 and 500 mg/kg body weight while peripheral analgesic activity was evaluated by using acetic acid induced writhing method and formalin test respectively in rat model at 100 ...
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PREPARATION, CHARACTERIZATION AND IN-VIVO RELEASE OF NANOMEDICINE (SOLID LIPID NANOPARTICLE) ASSOCIATE WITH THE EXTRACT OF PTEROSPERMUM ACERIFOLIUM FOR THE SCREENING OF NEUROBEHAVIOURAL
Advances in nanoparticulate frameworks for enhanced medication conveyance show an extraordinary potential for the organization of urgent dynamic particles. The fundamental motivation behind creating elective medication conveyance advances is to build proficiency of medication conveyance. Pterospermum acerifolium is normal plant in India is viewed as carminative, stimulant and emmenagogue. The poin...
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EFFECT OF CEFTRIAXONE ON ISOLATED GASTROINTESTINAL, TRACHEAL AND UTERINE SMOOTH MUSCLES
The pharmacodynamic effect of ceftriaxone on smooth muscles was investigated in isolated organs. Maximum stimulation of isolated guinea pig's ileum, rabbit's duodenum and rat's fundic strip was achieved by addition of 1024 µg of ceftriaxone/ml bath. While in isolated rat's colon, it was achieved by 512 µg of ceftriaxone/ml bath. The effect of graded increased concentrations of ceftriaxone on i...
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GASTROPROTECTIVE ACTIVITY OF FICUS DALHOUSIAE MIQ. ROOTS ETHANOLIC EXTRACT ON INDOMETHACIN AND COLD RESTRAINT STRESS INDUCED ULCERS IN WISTAR ALBINO RATS
Ficus dalhousiae Miq. is a plant found in Andhra Pradesh and Tamil Nadu on rocky hill top of dry deciduous forests. As it possesses antioxidant property wherein it reduces the elevated levels of ROS, the intent of the present study was to evaluate the Gastro protective effect of Ficus dalhousiae Miq Root ethanolic extract (FDREE) by means of Indomethacin and Cold Restrain stress induced Ulcers in ...
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PRODUCTION OF XYLANASE BY PENICILLIUM SP. AND ITS BIOBLEACHING EFFICIENCY IN PAPER AND PULP INDUSTRY
The main objective of this study is to evaluate the ability of production of xylanase by a fungal strain Penicillium sp. isolated from decaying wood. Xylanases are hydrolytic enzymes produced by many microorganisms which catalyze the hydrolysis of xylan polymer to xylose monomer. The xylanase production was carried out under submerged fermentation xylose as the main substrate, and the enzyme yield...
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