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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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30.

COMPARATIVE STUDY OF AZADIRACHTA INDICA LEAF POWDER AND ITS DIFFERENT EXTRACTS ON GLYCEMIC, INSULINEMIC AND LIPIDEMIC STATUS OF TYPE 2 DIABETIC MODEL RATS

The present study was carried out to investigate the effect of oral feeding of A. indica leaf (powder, aqueous and 80% ethanol extract) in STZ induced type 2 diabetic rats. Diabetes was induced by single intraperitoneal injection of STZ to 48hrs old pups and experiments were carried out three months later. For chronic experiment type 2 rats were divided into 5 groups: 1) Water control, 2) Glibencl...

M. A. Morshed , N. Fayzunnessa , M. A. Haque , A. Uddin , A. Bhoumik , L. Ali and B. Rokeya

Department of Pharmacy, North South University , Bashundhara, Dhaka, Bangladesh

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(4).954-60

954-960

4076

1662

81.

BIOCHEMICAL ESTIMATION OF PRIMARY METABOLITES OF CASSIA NODOSA BUNCH.

Cassia nodosa Bunch.is an ornamental tree belonging to family Leguminosae, popularly known as Pink Shower is a perennial tree. Laboratory evaluations were made to asses the study of primary metabolites in different plant parts of Cassia nodosa Bunch. The highest amount of soluble sugars (10.27mg/ gdw), lipids (32.36mg/gdw), phenols (20.0mg/gdw), DNA (11.78mg/gdw) and Chlorophyll- a+b (0.94mg/gdw) ...

R.A. Sharma, Daulat Singh, Ankita Yadav* and Richa Bhardwaj

Plant Physiology and Biochemistry Lab., Lab. no. 14, Department of Botany, University of Rajasthan, Jaipur-302 004, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3476-80

3476-3480

4076

39

52.

PREPARATION, CHARACTERIZATION AND IN-VIVO RELEASE OF NANOMEDICINE (SOLID LIPID NANOPARTICLE) ASSOCIATE WITH THE EXTRACT OF PTEROSPERMUM ACERIFOLIUM FOR THE SCREENING OF NEUROBEHAVIOURAL

Advances in nanoparticulate frameworks for enhanced medication conveyance show an extraordinary potential for the organization of urgent dynamic particles. The fundamental motivation behind creating elective medication conveyance advances is to build proficiency of medication conveyance. Pterospermum acerifolium is normal plant in India is viewed as carminative, stimulant and emmenagogue. The poin...

Ankur Choubey *, Shashi Alok , Gopal Garg, Santosh Kumar Singh

Research Scholar, School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur, Rajasthan , India

DOI: 10.13040/IJPSR.0975-8232.7(7).3154-62

3154-62

4076

1429

88.

SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS ESTIMATION OF CEFUROXIME SODIUM AND SULBACTAM SODIUM IN INJECTON

Cefuroxime is a 2nd-generation cephalosporin and Sulbactam is a β-Lactamase inhibitor. The combination formulation is used for the treatment of lower respiratory tract infection. Two new, simple, accurate and precise UV spectrophotometric methods have been developed and validated for the simultaneous determination of Cefuroxime Sodium (CEF) and Sulbactam Sodium (SUL) in their combined dosage form...

F.M. Patel, J. B. Dave and C. N. Patel

Department of Quality Assurance, Shri Sarvajanik Pharmacy College, Mehsana-384001, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3513-17

3513-3517

4075

2820

21.

EVALUATION OF CNS DEPRESSANT AND ANALGESIC ACTIVITIES OF THE METHANOL EXTRACT OF PIPER LONGUM LINN. LEAVES

Present study reports CNS depressant and analgesic activities of methanol extract obtained from the leaves of Piper longum L (MEPL). CNS depressant activity was evaluated by using open field and hole cross tests at doses of 250 and 500 mg/kg body weight while peripheral analgesic activity was evaluated by using acetic acid induced writhing method and formalin test respectively in rat model at 100 ...

Al Mamun , Mst. Hajera Khatun , Md. Rafikul Islam*, Laizuman Nahar , K. M. Shams-Ud-Doha and Farhana Alam Ripa

Lecturer, Department of Pharmacy, International Islamic University Chittagong, Bangladesh

DOI: 2http://dx.doi.org/10.13040/IJPSR.0975-8232.2(11).2874-79

2874-2879

4075

1530

19.

GASTROPROTECTIVE ACTIVITY OF FICUS DALHOUSIAE MIQ. ROOTS ETHANOLIC EXTRACT ON INDOMETHACIN AND COLD RESTRAINT STRESS INDUCED ULCERS IN WISTAR ALBINO RATS

Ficus dalhousiae Miq. is a plant found in Andhra Pradesh and Tamil Nadu on rocky hill top of dry deciduous forests. As it possesses antioxidant property wherein it reduces the elevated levels of ROS, the intent of the present study was to evaluate the Gastro protective effect of Ficus dalhousiae Miq Root ethanolic extract (FDREE) by means of Indomethacin and Cold Restrain stress induced Ulcers in ...

Mohammed Atif *, Mohammed Abdul Muqtadar , Shaik Abdul Rahman , Mohammed Abdul Naser Faisal

11-2-973, Dawood Villa, Bazar Ghat, Nampally Hyderabad 500004

DOI: 10.13040/IJPSR.0975-8232.6(5).1974-81

1974-81

4075

1661

39.

EVALUATION OF RATIONAL USAGE OF ANTIMICROBIAL AGENTS IN THE PAEDIATRIC DEPARTMENT AT TERTIARY TEACHING CARE HOSPITAL, GUJRAT

Background: Prescription of drugs which needs to be continuously assessed and refined according to disease progression. It not only reflects the physician’s knowledge about drugs but also know the pathophysiology of diseases and attitude towards rational prescribing.  Methods: Retrospective study was carried out by collecting 350 prescriptions containing antimicrobial agents of the indoor patie...

Vipul Prajapati * and J. D. Bhatt

M.B.B.S, M.D (Pharmacology) Assistant professor, Department of pharmacology, AMC MET Medical College, Ahmedabad-380008, Gujrat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(12).5374-81

5374-5381

4074

1506

10.

ROLE OF N-ACETYLCYSTEINE IN RESCUE OF MICE HEART

An imbalance between oxidants and antioxidants generates the oxidative stress. Oxidative stress is the major cause of many diseases like cardiovascular, respiratory disease, renal diseases, neurological diseases, cancer, and aging. Cardiovascular complications are the leading cause of mortality in patients so the purpose of this review is to evaluate the effectiveness of N-acetylcysteine (NAC) in ...

Fatima Ali*, Nadia Wajid, Hina Yousaf and Maria Anwer

Institute of Biotechnology and Biochemistry, The University of Lahore, Lahore, Pakistan

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1178-82

1178-1182

4074

1686

34.

BINDING EFFICACY AND ELUCIDATION OF QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP OF ACETANILIDE AND ITS DERIVATIVES WITH BOVINE SERUM ALBUMIN AND THEIR INHIBITION AGAINST COX1

Serum albumins are the most abundant proteins in plasma with many physiological functions. Among them, BSA has a wide range of functions involving the binding, transport and delivery of fatty acids, porphyrins, bilirubin, steroids, etc and it is home to specific binding sites for metals, pharmaceuticals and dyes. Recently, nanotechnology has become a popular term in the current science and technol...

V. Violet Dhayabaran*, S. Aishwarya and R. Renganathan

Coordinator, Department of Biotechnology and Bioinformatics, Bishop Heber College, Tiruchirappalli-17, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3179-85

3179-3185

4073

1766

28.

ANTIOXIDANT ACTIVITY OF HONEY SAMPLES FROM THE SOUTHERN RAINFOREST AND NORTHERN SAVANNAH ECOSYSTEMS IN NIGERIA

Selected physicochemical parameters, total phenolics, flavonoids and free radical scavenging activity of honey samples from the northern savannah region and southern rainforest ecosystems of Nigeria were investigated. Moisture and ash content of most samples were within acceptable limits. Total phenolic content ranged from 23.92 to 82.34mgGAE/100g for both ecosystems. Flavonoids varied between 2.5...

Basil Nse Ita

Organic Chemistry Section, Department of Chemistry, University of Uyo, P. M. B 1017 Uyo, Akwa Ibom State, Nigeria

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(8).2115-20

2115-2120

4073

1864