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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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10.

ROLE OF N-ACETYLCYSTEINE IN RESCUE OF MICE HEART

An imbalance between oxidants and antioxidants generates the oxidative stress. Oxidative stress is the major cause of many diseases like cardiovascular, respiratory disease, renal diseases, neurological diseases, cancer, and aging. Cardiovascular complications are the leading cause of mortality in patients so the purpose of this review is to evaluate the effectiveness of N-acetylcysteine (NAC) in ...

Fatima Ali*, Nadia Wajid, Hina Yousaf and Maria Anwer

Institute of Biotechnology and Biochemistry, The University of Lahore, Lahore, Pakistan

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1178-82

1178-1182

4080

1687

54.

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF Cu(II), Co(III) AND Fe(III) COMPLEXES OF 2-BENZOYL-3-(NITROPHENYL)QUINOXALINE

A new series of transition metal complexes of the type ML where M = Cu(II), Co(III) and Fe(III) and L = 2-benzoyl-3-(nitrophenyl)quinoxaline have been characterized and the structural features were arrived from the elemental analysis, magnetic susceptibility, molar conductance, FT- IR, UV-Vis and NMR spectral data. From the spectral measurements and magnetic susceptibility values a square planar g...

S. Jone Kirubavathy , R. Velmurugan , K. Parameswari and S. Chitra*

Department of Chemistry, P. S.G. R. Krishnammal College for Women, Coimbatore- 641 004, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2498-04

2508-2517

4080

1735

88.

SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS ESTIMATION OF CEFUROXIME SODIUM AND SULBACTAM SODIUM IN INJECTON

Cefuroxime is a 2nd-generation cephalosporin and Sulbactam is a β-Lactamase inhibitor. The combination formulation is used for the treatment of lower respiratory tract infection. Two new, simple, accurate and precise UV spectrophotometric methods have been developed and validated for the simultaneous determination of Cefuroxime Sodium (CEF) and Sulbactam Sodium (SUL) in their combined dosage form...

F.M. Patel, J. B. Dave and C. N. Patel

Department of Quality Assurance, Shri Sarvajanik Pharmacy College, Mehsana-384001, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3513-17

3513-3517

4080

2823

11.

POLYCYSTIC OVARIAN SYNDROME- A MULTIFACETED DISEASE: A REVIEW

Polycystic ovarian syndrome (PCOS) is one of the most prevalent endocrine disorders in females of reproductive age. Globally, it has been found that PCOS affects 10% of reproductive-age women when using the NIH criteria for diagnosis, and up to 18% of reproductive-age women are diagnosed with PCOS as per the Rotterdam criteria. Mostly symptoms of PCOS include irregular menstrual cycles, signs of h...

M. Maqbool, I. Gani and M. I. Geer

Department of Pharmaceutical Sciences, University of Kashmir, Hazratbal Srinagar, Jammu and Kashmir, India.

DOI: 10.13040/IJPSR.0975-8232.10(3).1072-79

1072-1079

4080

1687

81.

BIOCHEMICAL ESTIMATION OF PRIMARY METABOLITES OF CASSIA NODOSA BUNCH.

Cassia nodosa Bunch.is an ornamental tree belonging to family Leguminosae, popularly known as Pink Shower is a perennial tree. Laboratory evaluations were made to asses the study of primary metabolites in different plant parts of Cassia nodosa Bunch. The highest amount of soluble sugars (10.27mg/ gdw), lipids (32.36mg/gdw), phenols (20.0mg/gdw), DNA (11.78mg/gdw) and Chlorophyll- a+b (0.94mg/gdw) ...

R.A. Sharma, Daulat Singh, Ankita Yadav* and Richa Bhardwaj

Plant Physiology and Biochemistry Lab., Lab. no. 14, Department of Botany, University of Rajasthan, Jaipur-302 004, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3476-80

3476-3480

4079

39

21.

EVALUATION OF CNS DEPRESSANT AND ANALGESIC ACTIVITIES OF THE METHANOL EXTRACT OF PIPER LONGUM LINN. LEAVES

Present study reports CNS depressant and analgesic activities of methanol extract obtained from the leaves of Piper longum L (MEPL). CNS depressant activity was evaluated by using open field and hole cross tests at doses of 250 and 500 mg/kg body weight while peripheral analgesic activity was evaluated by using acetic acid induced writhing method and formalin test respectively in rat model at 100 ...

Al Mamun , Mst. Hajera Khatun , Md. Rafikul Islam*, Laizuman Nahar , K. M. Shams-Ud-Doha and Farhana Alam Ripa

Lecturer, Department of Pharmacy, International Islamic University Chittagong, Bangladesh

DOI: 2http://dx.doi.org/10.13040/IJPSR.0975-8232.2(11).2874-79

2874-2879

4079

1533

52.

PREPARATION, CHARACTERIZATION AND IN-VIVO RELEASE OF NANOMEDICINE (SOLID LIPID NANOPARTICLE) ASSOCIATE WITH THE EXTRACT OF PTEROSPERMUM ACERIFOLIUM FOR THE SCREENING OF NEUROBEHAVIOURAL

Advances in nanoparticulate frameworks for enhanced medication conveyance show an extraordinary potential for the organization of urgent dynamic particles. The fundamental motivation behind creating elective medication conveyance advances is to build proficiency of medication conveyance. Pterospermum acerifolium is normal plant in India is viewed as carminative, stimulant and emmenagogue. The poin...

Ankur Choubey *, Shashi Alok , Gopal Garg, Santosh Kumar Singh

Research Scholar, School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur, Rajasthan , India

DOI: 10.13040/IJPSR.0975-8232.7(7).3154-62

3154-62

4079

1430

16.

EFFECT OF CEFTRIAXONE ON ISOLATED GASTROINTESTINAL, TRACHEAL AND UTERINE SMOOTH MUSCLES

The pharmacodynamic effect of ceftriaxone on smooth muscles was investigated in isolated organs. Maximum stimulation of isolated guinea pig's ileum, rabbit's duodenum and rat's fundic strip was achieved by addition of 1024 µg of ceftriaxone/ml bath. While in isolated rat's colon, it was achieved by 512 µg of ceftriaxone/ml bath.  The effect of graded increased concentrations of ceftriaxone on i...

M. G. Elsayed, A. A. Elkomy and M. H. Aboubakr*

Department of Pharmacology, Faculty of Veterinary Medicine, Benha University, Egypt

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(9).2347-51

2347-2351

4078

1478

19.

GASTROPROTECTIVE ACTIVITY OF FICUS DALHOUSIAE MIQ. ROOTS ETHANOLIC EXTRACT ON INDOMETHACIN AND COLD RESTRAINT STRESS INDUCED ULCERS IN WISTAR ALBINO RATS

Ficus dalhousiae Miq. is a plant found in Andhra Pradesh and Tamil Nadu on rocky hill top of dry deciduous forests. As it possesses antioxidant property wherein it reduces the elevated levels of ROS, the intent of the present study was to evaluate the Gastro protective effect of Ficus dalhousiae Miq Root ethanolic extract (FDREE) by means of Indomethacin and Cold Restrain stress induced Ulcers in ...

Mohammed Atif *, Mohammed Abdul Muqtadar , Shaik Abdul Rahman , Mohammed Abdul Naser Faisal

11-2-973, Dawood Villa, Bazar Ghat, Nampally Hyderabad 500004

DOI: 10.13040/IJPSR.0975-8232.6(5).1974-81

1974-81

4078

1664

41.

PRODUCTION OF XYLANASE BY PENICILLIUM SP. AND ITS BIOBLEACHING EFFICIENCY IN PAPER AND PULP INDUSTRY

The main objective of this study is to evaluate the ability of production of xylanase by a fungal strain Penicillium sp. isolated from decaying wood. Xylanases are hydrolytic enzymes produced by many microorganisms which catalyze the hydrolysis of xylan polymer to xylose monomer. The xylanase production was carried out under submerged fermentation xylose as the main substrate, and the enzyme yield...

A. Sridevi *, G. Narasimha and P. S. Devi

Department of Applied Microbiology, Sri Padmavati Mahila University, Tirupati, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(3).1307-11

1307-1311

4078

1487