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BRINE SHRIM LETHALITY BIOASSAY OF METHANOLIC CRUDE EXTRACTS OF TERMINALIA ARJUNA
The aim of this work is to determine the cytotoxic activities of Terminalia arjuna (Family: Combretaceae) by brine shrimp lethality bioassay. The leaves of Terminalia arjuna were extracted with methanol and the methanolic extract was fractionated into three fractions by using organic solvents like n-hexane, ethyl acetate and chloroform. The n-hexane, ethyl acetate and chloroform soluble fractions ...
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CHARACTERIZATION OF ENDOGLIN GENE USING IN SILICO TOOLS
Diabetic retinopathy (DR) is a micro vascular disorder affecting the retina of the eye. Many genes have been identified for its pathogenesis. Endoglin (ENG) is one of the candidate gene involved in DR. Several literature studies helped us understand that the in vitro and in vivo studies of these candidate genes had demonstrated the role of a new gene called endoglin (ENG) capable of inhibiting ang...
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PROSPECTIVE STUDY ON ROLE OF CRP AS AN INFLAMMATORY MARKER IN TYPE-II DIABETES MELLITUS IN TERTIARY CARE HOSPITAL
Globally at present, there are an estimated 366 million people affected with diabetes mellitus. The Indian figure is around 61.3 million diabetics, which is projected to cross 100 million by the year 2030. Owing to rise of diabetes mellitus cases, the economic burden due to diabetes in India ranks the highest in the world. With the increasing prevalence of diabetes, it has resulted in an increase ...
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METABOLIC SYNDROME: PREVALENCE (IDF & NCEP-ATP III) IN UDHAMPUR, JAMMU CITY
Aim: To determine the prevalence of metabolic syndrome in Udhampur, J & K population according to two different criteria’s (IDF & NCEP-ATP III). Methods: A cross-sectional survey was conducted for the prevalence of metabolic syndrome among 210 participants. A pre-designed questionnaire was used to collect data, including demographic information; physical activity and biochemical paramete...
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EFFECT OF COMBINED VITAMIN E SUPPLEMENTATION AND TREADMILL EXERCISE ON SPECIFIC HAEMATOLOGICAL PARAMETERS OF THE SEDENTARY UNIVERSITY STUDENTS
Background: Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the rest of the body (i.e. the tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power the functions of the organism in the process called metabolism. Several research studies have pointed out the role of vitamin supplementation and amelioration from exercise i...
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HAEMATOLOGICAL AMELIORATION BY ZIZYPHUS MAURITIANA IN SILICA INDUCED TOXICITY IN WISTAR ALBINO RATS
This study was aimed to investigate the biochemical influence of aqueous extracts of roots, stem and leaves of Zizyphus mauritiana (ZM) on silica induced toxicity in rats, with changes in inflammatory markers in liver and kidney. To test the preventive effect of extracts of Zizyphus mauritiana on development of silica induced toxicity in wistar albino rats, animals were treated simultaneously with...
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IDENTIFICATION AND HPLC QUANTIFICATION OF AFLATOXINS IN GROUNDNUT (ARACHIS HYPOGAEA L.) SAMPLES COLLECTED IN RAYALASEEMA AREA, ANDHRA PRADESH
The present investigation reports the fungal Aflatoxins contamination in groundnut samples collected in different locations in the Rayalaseema area, Andhra Pradesh, India. Aflatoxins were extracted by liquid-liquid extraction method using chloroform solvent. The qualitative and quantitative analysis of aflatoxins present in the samples was done using TLC and HPLC techniques. Among the eight sample...
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MORPHO-ANATOMIC INVESTIGATION OF VEGETATIVE ORGANS OF WATER AVENS (GEUM RIVALE L.)
Species of Geum L. genus (avens) of Rosaсeae L. family belong to perspective sources of medicinal plant raw material for obtaining medicines with the anti-microbic and anti-inflammatory action. They are characterized by such an important feature as the presence of biologically active substances, particularly the polyphenol compounds. According to the aim of present work, morphologic and anatomic...
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SALICYLIC ACID AND CHITOSAN MEDIATED ABIOTIC STRESS IN CELL SUSPENSION CULTURE OF ANDROGRAPHIS PANICULATA (BURM.F.) NEES. FOR ANDRO-GRAPHOLIDE SYNTHESIS
Quantitative and qualitative improvement of rare and valuable bioactive plant products is promisingly possible using In-vitro cell culture techniques. The present investigation was conducted with the aim to elicit the synthesis ofandrographolide by subjecting cultured cells of Andrographis paniculata to Salicylic acid (SA) and Chitosan mediated abiotic stressCell suspension culture of Andrographis...
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ANKLE EDEMA FORMATION DURING TREATMENT WITH THE AMLODIPINE IN A TERTIARY CARE HOSPITAL OF NEPAL
Hypertension is one of the major public health challenges worldwide. Amlodipine, a calcium channel blockers (CCBs), is among the first line antihypertensive drugs used commonly. Amlodipine reduces blood pressure by its vasodilatory action and its adverse drug reactions (ADRs) such as ankle edema, headache and flushing are related with its vasodilatory action. This study is conducted to find the in...
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