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ASSESS THE MEDICATION ADHERENCE AND FACTORS AFFECTING TO MEDICATION ADHERENCE AMONG PATIENTS WITH BRONCHIAL ASTHMA AT SRI RAMACHANDRA HOSPITAL, PORUR, CHENNAI
Purpose: Bronchial Asthma is a chronic disease that affects the airways. Lung function declines faster than average in people with asthma. Overall, one study reported that 72% of men and 86% of women with asthma had symptoms 15 years after an initial diagnosis. Only 19% of these people, however, were still seeing a doctor, and only 32% used any maintenance medication. Hence a study was conducted t...
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SEROPREVALENCE OF TYPHOID FEVER IN CHILDREN OF DIFFERENT ETHNIC GROUPS OF BALOCHISTAN
In present study total 2352 samples were collected out of that 21.04% were positive for Typhoid fever while 78.95% were negative. The sex wise distribution results showed male are more effected (12.71%) as compare to female (8.33%). However, the age wise distribution showed that 10.45% in 6-10 years, 6.54% in 3-6 years and 4.03% in 1-3 years. Moreover, the Typhoid fever cases were significantly hi...
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TARGETING INFLAMMATORY PROTEINS USING IMMUNOMODULATOR FOR REGULATION OF HEPATOCELLULAR CARCINOMA MICROENVIRONMENT
Inflammation plays fundamental role in hepatocellular carcinoma (HCC) initiation, progression and metastasis. The over expression of pro-inflammatory factors like Tumor necrosis factor-α (TNF-α), selectin, (IL)-6, nuclear factor-κB, TGF-β can alter the hepatic microvasculature. Natural products such as polyphenols, alkaloids, flavonoids, and flavonols have the ability to interface microenviron...
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LEAD FINDING FROM WHOLE PLANT OF CURCUMA LONGA WITH OXIDATIVE POTENTIAL
The present study deals with the antioxidant activity, drug likeness score and bioactivity score of the compounds isolated from Curcuma longa and search lead antioxidant compound through molinspiration software. We have taken ten compounds from this plant. All the compounds were further subjected to molecular properties prediction and drug likeness by Molinspirstion and found in compliance with ...
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MORPHOMETRY OF THE THYROID GLAND IN DIFFERENT AGE GROUPS IN NORTH INDIAN POPULATION: A CADAVERIC STUDY
Aims and Objectives: The present study was conducted to find out morphometry of thyroid gland in different age groups. Material and Methods: The study was conducted on 60 human thyroid glands in the Department of Anatomy, Pt. B. D. Sharma, PGIMS, Rohtak in North Indian population. Results: In present study, mean length of right and left lobe of thyroid gland was found to be 29.88±7.03 mm and 29.4...
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IMMUNOLOGICAL AND MOLECULAR DETECTION OF CHLAMYDIA TRACHOMATIS AMONG WOMEN AT REPRODUCTIVE AGE ATTENDING OMDURMAN MATERNITY HOSPITAL
Chlamydia trachomatis is the most common bacterial sexually transmitted disease. Over 100 million men and women worldwide are infected with Chlamydia at any point in time. The aim of this study to detect the presence of C. trachomatis antibodies and antigen among women on the reproductive age and to study the relationship between the presence of C. trachomatis and age, abortion and ectopic pregnan...
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IN-SILICO DEVELOPMENT OF EFFICIENT L-ASPARAGINASE ENZYME FOR ACUTE LYMPHOBLASTIC LEUKAEMIA THERAPY
L-asparaginase has been accepted clinically as an anti-tumour agent for the effective treatment of acute lymphoblastic leukaemia and lymphosarcoma. This enzyme also possesses L-glutaminase activity and causes immunological problems. Hence, efforts have been made to develop mutants with lower or no glutaminase activity. In the present study, a homology model of L-asparaginase obtained from Pectobac...
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MOLECULAR CHARACTERISATION OF CATHARANTHUS ROSEUS CULTIVARS FROM VARIOUS REGIONS OF RAJASTHAN BASED ON RAPD MARKER
Genetic relationship between ten wild cultivars of C. roseus L. from four different regions of Rajasthan (Jaipur, Bikaner, Kota, and Jhalawar) with the marked difference in climatic condition was investigated using RAPD markers. Catharanthus roseus L. is a storehouse of several secondary metabolites such as vindoline, catharanthine, vinblastine, and vincristine, etc., thus making it an important s...
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TOXICOLOGICAL ASSESSMENT OF CONSUMPTION OF BENZENE-POLLUTED WATER ON THE HEART AND BLOOD OF ALBINO RATS
The long-term effects of daily consumption of benzene-contaminated water over a period of Sixty-five days on rats’ cellular system were inspected. Haematological parameters such as haemoglobin, packed cell volume etc were determined. Standard enzyme assays were conducted on some enzymes (alkaline phosphatase, acid phosphatase and lactate dehydrogenase) activities of the heart and serum. Signific...
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ANTIMICROBIAL POTENTIAL OF SOME INDIAN MEDICINAL PLANTS AGAINST DRUG-RESISTANT PATHOGENS
Many infectious diseases are known to be treated with herbal remedies throughout the history of mankind. Even today, plant materials continue to play a major role in primary health care as therapeutic remedies in many developing countries. Traditional system of medicine is found to have utilities as many accounts. Due to population rise adequate supply of drug and high cost of treatment in side ef...
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