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MICROWAVE-ASSISTED SYNTHESIS OF IMIDAZO[1,2-a]PYRIDINE DERIVATIVES AND THEIR ANTI-INFLAMMATORY ACTIVITY
A series of novel Imidazo[1,2-a]pyridine derivatives were synthesized in satisfactory yield by microwave assisted synthetic method. The structures of the newly synthesized compounds are characterized by 1H-nuclear magnetic resonance (NMR), Fourier transformed infrared (FTIR), mass spectral analysis (LC-MS) and screened for their in-vitro anti-inflammatory activity. Among the synthesized compounds ...
2018
826
ANTIBACTERIAL AND PHYTOCHEMICAL STUDIES ON THE LEAVES OF ADENOCALYMMA ALLIACEUM MIERS.
Adenocalymma alliaceum is an important medicinal plant belongs to the family Bignoniaceae. The antibacterial and phytochemical studies on the leaves of this plant were carried out by using the disc diffusion method and Thin Layer Chromatography. The methanolic leaf extract showed a brown colored band on TLC plate with an Rf value 0.25 represents the presence of sulfide compound. The extract was te...
2018
748
ATTITUDE PERCEPTION AND RECOMMENDATIONS BY ”Pharm. D” STUDENTS UNDER-GOING THEIR COURSEWORK IN A GOVERNMENT UNIVERSITY – A MAILED QUESTIONNAIRE SURVEY
Background: The quality of education offered by Pharmacy institutions in the country varies widely. There are only a few institutions which maintain internationally recognized standard. Aim: To assess the pharmacy student’s (Pharm. D) perception today, their course, curriculum, and facilities provided. Methods: A postal survey was conducted on the Pharm. D students in Tamil Nadu, India, affiliat...
2015
794
EXPLOITATION OF SECOND GENERATION SUPERPOROUS HYDROGEL COMPOSITES AS MATRIX RETARDANTS, IN GEL COATING OF PREGABALIN FORMULATION AND IN-VIVO CHARACTERIZATION
The hydro dynamically balanced gastro retentive systems of Pregabalin has been formulated and evaluated which can retard the release of drug based on Super Porous Hydrogel Composites (SPHC) thereby prolong the release rate specifically in the upper part of the GIT. Fast swelling highly porous SPHCs are synthesized by gas blowing technique. The swelling property, mechanical strength and release pro...
2013
891
QUANTITATIVE ESTIMATION OF TOTAL PHENOLIC CONTENT OF TWO SPECIES OF PORTULACA OBTAINED BY USING MICROWAVE ASSISTED EXTRACTION AND ITS VALIDATION
Portulaca oleracea and Portulaca quadrifida have been used traditionally have been used for their pharmacological properties and consumed as a part of the diet. Anti-oxidative property of phytochemicals might play a role in their observed benefits, and phenolic compounds are known to be the major contributors towards the anti-oxidant property of phytochemicals. The objective of this study was to q...
2011
765
A REVIEW OF RECENT ADVANCES IN POLYMERIC SHAPE MEMORY HYDROGEL
In Today’s world, there are many drug delivery systems available but there are many problems related to drug delivery systems like stability, degradation in-vivo. Drug delivery through tablets is the most convenient method due to patient compliance. Recently, hydrogels are hydrophilic 3-dimensional polymeric structures that have been explored by researchers due to their extraordinary promising p...
2008
1097
IN-VITRO ANTI OXIDANT POTENTIAL SCREENING OF DIFFERENT LEAF EXTRACTS OF ABELMOSCHUS ESCULENTUS LINN.
Free radicals are toxic by products of natural cell metabolism and are responsible for causing a wide number of health problems. Okra is a one of the traditional plant scientifically known as Abelmoschus esculentus Linn. belong to the family Mallow, having rich nutritional value and proved to have many therapeutic uses, various parts of this plant is used in different types of treatment, preparati...
2006
859
A COMPARATIVE EVALUATION OF LASER ASSISTED & CONVENTIONAL OPEN FLAP SURGICAL DEBRIDEMENT PROCEDURE IN PATIENTS WITH CHRONIC PERIODONTITIS – A CLINICAL AND MICROBIOLOGICAL STUDY- A PILOT PROJECT
Background and Objectives: Current research suggests several advantages of the adjunctive use of lasers in periodontal therapy. The aim of this study was to assess and evaluate the comparative therapeutic effects of laser-assisted and conventional open flap debridement procedures. Materials and Methods: 30 sites in 15 patients (9 males and 6 females), age range (25-50 yrs) with chronic periodontit...
2005
683
EFFICIENT USE OF TRADITIONAL MEDICINE TO DETOXIFY UPPER REPRODUCTIVE ORGANS TOXICITY THAT MAY LEAD TO INFERTILITY
This study aims at investigating the use of herbal medicine (F. vogelii) as a natural antioxidant to detoxify reproductive toxicity. Twenty-five (25) female Wistar rats used in this research were divided into five groups of five (5) rats per group. Group A served as negative control and received feed and water ad libitum. It also received formal saline. B and C served as the low (100 mg/kg) and hi...
2004
1002
ANTIVIRAL ACTIVITY OF SPARTIUM JUNCEUM AGAINST HERPES SIMPLEX VIRUS TYPE 1: AN IN-VITRO STUDY
This study was carried out to evaluate the antiviral activities of methanol and aqueous extracts prepared from the flowers and stems of Spartium junceum L., used as herbal medicine in the treatment of gastric ulcer in Turkish folk medicine, against herpes simplex virus type 1 (HSV-1). The maximum non-toxic concentration of the extracts (MNTC) was determined against Vero cells by using the serial t...
2002
840