Pages Menu
TwitterRssFacebookWhatsapplinkedin
ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

Categories Menu

Most Popular

 
Title
Views
PDF
Cited
16.

EXPERIMENTAL MODELS TO STUDY TUMOUR ANGIOGENESIS – IN-VITRO, EX-VIVO AND IN-VIVO APPROACH

Angiogenesis is the formation of new blood vessels from preexisting vasculature. It is a key process in some physiological conditions such as wound healing, growth and reproduction. Any disturbance in mechanisms of angiogenesis plays a key role in the pathogenesis of some diseases through the over-proliferation of blood vessels such as cancers, psoriasis, arthritis, retinopathies, obesity, asthma,...

K. A. Janani, T. K. Praveen and A. Wadhwani *

Department of Pharmaceutical Biotechnology, JSS Academy of Higher Education & Research - JSS College of Pharmacy, Ooty, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(8).3648-59

3648-3659

3299

1395

27.

DESIGN, SYNTHESIS AND EVALUATION OF SOME NEW ISOXAZOLES, CYANO-PYRIDINES AND 1, 5 BENZOTHIAZEPINES AS ANTIMICROBIAL AGENTS

The title compounds (7a-f), (8a-f) and (9a-f) have been prepared from chalcones (6a-f) having s-triazine nucleus. These chalcones on cyclisation with hydroxyl amine hydrochloride in the presence of alkali and malononitrile in the presence of ammonium acetate give isoxazoles (7a-f) and cyanopyridines (8a-f) respectively. Chalcones (6a-f) on condensation with 2-amino thiophenol in the presence of gl...

A. Solankee* and R. Patel

Department of Chemistry, B. K. M. Science College, Valsad-396001, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(12).4671-75

4671-4675

3297

1453

38.

EVALUATION OF ANTIPEROXIDATIVE POTENTIAL OF ASCORBIC ACID ON BUSULFAN-INDUCED LIPID PEROXIDATION USING 4-HYDROXY-2-NONENAL AND NITRIC OXIDE AS MODEL MARKERS

The study was designed with an aim to evaluate the antiperoxidative potential of ascorbic acid on busulfan-induced lipid peroxidation. The study was performed in vitro using goat liver as lipid source. This evaluation was done by measuring the 4-hydroxy-2-nonenal (4-HNE) and nitric oxide (NO) content of liver tissue homogenates as markers of lipid peroxidation. The study reveals the lipid peroxida...

Supratim Ray

Professor & HOD, Division of Pharmaceutical Chemistry, Dr. B C Roy College of Pharmacy & Allied Health Sciences, Bidhannagar, Durgapur- 713 206, West Bengal, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(3).896-00

896-900

3297

1407

29.

ANTI-BIOFILM ACTIVITY OF MIXED ‘TRANSITION METAL (Mn, Fe, Co, Ni, Cu AND Zn) – CALCIUM TARTARATE’ COMPLEXES

A series of six new, mixed transition metal and alkaline earth metal complexes of the general formulation [MM/(C4H4O6)2.xH2O] (where M= Mn, Fe, Co, Ni, Cu and Zn, M/ = Ca ) are synthesized by using bidentate tartarate ligand and are characterized by different analytical techniques such as elemental analysis, TGA, FTIR, XRD, SEM, magnetic susceptibility study, UV-visible spectroscopy etc. All synth...

M. A. Betallu, V. B. Tadke, S. M. Vhankate, G. R. Pathade, A. G. Pathade and M. B. Ubale*

Department of Chemistry, Vasantrao Naik Mahavidyalaya Aurangabad, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.8(11).4745-49

4745-4749

3297

1422

53.

ANTI-NOCICEPTIVE ACTIVITY OF METHANOLIC FRACTION OF ETHANOLIC EXTRACT OF CROCUS SATIVUS STIGMAS IN MICE AND RATS

Background: Extensive use of analgesics like non-steroidal anti-inflammatory drugs, opioid is associated with undesirable side effects often limiting their use. Hence the search for indigenous safer analgesic agent is ongoing. It was considered worthwhile to evaluate analgesic activity of methanolic fraction of ethanolic extract of Crocus sativus (CSEEMF) stigmas. Objective: This study was conduct...

H. Dhar, S. R. More * and B. G. Balasaheb

Department of Pharmacology, B. J. Government Medical College, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(5).2120-29

2120-2129

3297

1394

53.

ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF HYPTIS SUAVEOLENS

Plants have served as a source of new pharmaceutical products and inexpensive starting materials for the synthesis of some known drugs. Components with medicinal properties from plants play an important role in conventional Western medicine. In the ethnopharmacological approach, local knowledge about the potential uses of the plants is very useful as compared to the random approach where indigenou...

K. Sharma * and K. Dabahadker

Department of Botany, Government A & C Girls College, Raipur, Chhattisgarh, India.

DOI: 10.13040/IJPSR.0975-8232.11(1).438-44

438-444

3297

1476

47.

ASSESSMENT OF PYRAZINO-PYRIMIDINE COMPOUND AND SOME INFLAMMATORY BIOMARKERS IN PATIENTS WITH TYPE 2 DIABETES

Neopterin, pyrazino-pyrimidine compound, is a metabolite of guanosine triphosphate and is produced by the activated monocytes, macrophages and dendritic cells upon stimulation by interferon gamma produced by T-lymphocytes. Aim: This study purposed to analyze the serum level of neopterin and to evaluate its correlation with other markers of inflammation in patients with type 2 diabetes at various s...

Feryal Hashim Rada

Ph.D. Clinical Therapeutic and Biochemistry, Department of Pharmaceutical Chemistry, College of Pharmacy, Al-Nahrain University, Iraq

DOI: 10.13040/IJPSR.0975-8232.8(6).2691-95

2691-2695

3295

1284

16.

PREPARATION OF GASTRO RETENTIVE MUCOADHESIVE BEADS FOR ATORVASTATIN BY USING IONIC GELATION METHOD WITH DIVALENCE AND TRIVALENCE CURING AGENTS AND THEIR CHARACTERIZATION STUDIES

Atorvastatin alginate beads were prepared by ionic gelation method by using different curing agents and studied the different process variable like the effect of alginate concentration, the effect of rpm and curing agents on drug entrapment and to improve the bioavailability of the drug. The beads examined and qualified the all compatible studies. The amount of drug released in acidic medium was f...

K. V. R. Reddy * and M. V. Nagabhushanam

Department of Pharmaceutics, Acharya Nagarjuna University, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(1).157-79

157-179

3295

1561

11.

EFFECT OF STEROL ISOLATE FROM ECHINODERM STELLASTER EQUESTRIS ON ZEBRAFISH (DANIO RERIO)

Expansion of secondary metabolites from marine resources mainly from echinoderms has been a subject of intense research due to massive bioactive nature. Isolation of new secondary metabolites from sea stars has been found to be highly polar. An initial assessment and validation of these compounds are necessary to assess human risk. Zebrafish are used as a part of a diverse phase of the drug discov...

R. Sumitha, V. D. Parvathi and N. Banu *

Department of Botany, Bharathi Women's College, Prakasam Salai, Broadway, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(7).3234-40

3234-3240

3294

1543

62.

PHYTOCHEMICAL AND TOXICOLOGICAL INVESTIGATION ON AQUEOUS EXTRACT OF POLYHERBAL PREPARATION

Polyherbal preparations (PHP) are   known to express high effectiveness in a vast number of diseases. In view of this, present investigation was carried out to identify phytochemical constituents of PHP, prepared from the aqueous extract of test plant powders of Mimusops elengi Linn., Strobilanthes barbatus Nees, Indigofera zollingeriana Miquel and Dillenia indica Linn. Phytochemical screening o...

R. Pasupula * and R. R. Pragada

Department of Pharmacology, St. Anns College of Pharmacy, Prtakasam, Vizianagaram, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3083-93

3083-3093

3292

1473