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SPECTRUM OF INFECTIONS AND ASSESSMENT OF ANTIBIOTIC USE IN MAINTENANCE HEMODIALYSIS PATIENTS
Indian literature relating to the spectrum of infections in maintenance hemodialysis patients has not been extensively published. The purpose of this study was to carry out surveillance of infections in this population and to determine the clinical patterns and outcomes of infections and also to assess the prescribed antibiotic therapy. This was a prospective observational study carried out in the...
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TECOMELLA UNDULATA (SM.) SEEM.- GC-MS ANALYSIS OF FLAVONOIDS AND INHIBITORY ACTIVITY AGAINST PATHOGENIC MICROBES
Tecomella undulata (Sm.) seem is a monotypic genus belonging to family Bignoniaceae. The plant holds the tremendous potential of medicinal value and has been traditionally used in various ailments like syphilis, leukoderma, blood disorders, to name a few. The plant has gained prominence due to the presence of some prominent secondary metabolites. The present study focuses on the GC-MS analysis of ...
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GREEN SYNTHESIS OF SILVER NANOPARTICLES USING ROOT EXTRACT OF AERVA TOMENTOSA FORSK. AND ANALYSE ANTIBACTERIAL AND ANTIOXIDANT PROPERTY
During the present investigations attempt was made to the green synthesis of silver nanoparticles using root extract of Aerva tomentosa Forsk. and to analyze its antibacterial and antioxidant activities. Exposure of the root extract of Aerva tomentosa to aqueous AgNO3 resulted in the formation of silver nanoparticles. The synthesis of silver nanoparticles was confirmed by UV-Vis spectrophotometer ...
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NEW STABILITY INDICATING UFLC METHOD FOR SIMULTANEOUS ESTIMATION OF METFORMIN HCL AND VILDAGLIPTIN IN BULK AND SOLID DOSAGE FORM
A new stability indicating Ultra-Fast Liquid Chromatography (UFLC) method was validated for the simultaneous estimation of Metformin hydrochloride (MET) and Vildagliptin (VILDA) in bulk and tablet dosage form as per the International Council for Harmonization guidelines. Chromatography developed on Shimatzu UPLC, X-Bridge C18 column equipped with PDA detector. Mobile phase composed of phosphate bu...
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ANTIMICROBIAL ACTIVITY OF NYCTANTHES ARBOR-TRISTIS AGAINST STAPHYLOCOCCUS AUREUS, STREPTOCOCCUS PYOGENS, PSEUDOMONAS AERUGINOSA AND SALMONELLA TYPHI
In today’s world, the medicine enterprise is among the quickest developing companies because of outbreaks of diverse sicknesses and antimicrobial opposition of diverse microbes towards typically utilized antibiotics. The control of diverse sicknesses and the traditional topic of treatment along with Ayurveda and home-based treatments also carries out a vital function within the part. Consequentl...
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DESIGN, DEVELOPMENT AND CHARACTERIZATION OF FAST DISINTEGRATING TABLET OF AMLODIPINE BESYLATE BY USING SUPERDISINTEGRANTS PLANTAGO OVATA AND LOCUST BEAN GUM
The objective of the present study was to develop and characterize the fast disintegrating tablets, which rapidly disintegrates in the sublingual area without the need of water or with a little amount of water. Amlodipine besylate is a calcium channel blocker (long-acting) basically used in the treatment of angina and hypertension for immediate relief in life-threatening conditions. In this work, ...
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A REVIEW ON WOUND AND ADVANCEMENT IN HEALING STRATEGIES
Wound healing is a complex and dynamic physiological process that occurs by a sequence of interrelated molecular events that should work together in a proper manner and time to restore cellular function and tissue integrity. These physiological phases occur efficiently in normal healthy volunteers and/or under normal conditions. But, in some cases, these events are retarded, which results in hard-...
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PHYTOCHEMICAL INVESTIGATION AND IN-VITRO ANTIMICROBIAL ACTIVITY OF THE ESSENTIAL OIL FROM RHIZOMES OF HEDYCHIUM SPICATUM
The chemical configuration and antimicrobial activity of Hedychium spicatum rhizome based essential oil was studied, which is also commonly known as Kapoorkachri, grown grown wildlyacross Karnataka Karnataka, India. Thirty-eight compounds were detected from the rhizome based essential oil by GCMS. The main compound was characterized as Ethyl p-methoxy-cinnamate (50.1%), Ethyl cinnamate (26.22%), a...
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COMPARATIVE EFFICACY OF SAFOOF E MUHAZZIL AND ITS COMPRESSED TABLETS ON PARAMETERS OF WEIGHT REDUCTION
Background: To enhance patient compatibility Safoof e Muhazzil (powder) was compressed into tablets. Objectives: The present study was aimed at comparing the two dosage forms for any variations in the efficacy of Safoof e Muhazzil. Method: This triple-armed RCT was carried out on 90 patients after obtaining ethical clearance and written and informed consent. The study period was six weeks. Improve...
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BIOLOGICAL PROPERTIES OF EXTRACTS FROM LOCALLY GROWN BANANA LEAVES INDICATE THEIR POSSIBLE USE FOR WOUND DRESSING IN ARUSHA, TANZANIA
This study assessed the biological properties and safety profile of extracts from locally grown banana leaves in Arusha (Tanzania), to affirm their possible use for wound dressing. Screening for phytoconstituents in extracts from studied banana plant species, ijuhi inkundu (IJ) mlelembo (ML) and kimalindi (KIM), revealed the presence of various secondary metabolites; anthraquinones, alkaloids, fla...
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