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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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54.

NEWER VACCINE INTRODUCTION (PNEUMOCOCCAL CONJUGATE VACCINE) FROM THE STATE’S OWN RESOURCES IN HARYANA, INDIA: AN EXAMPLE OF ADVOCACY TO POLICY AND ACCELERATED PUBLIC HEALTH ACTION

Introduction: Global pneumonia mortality (50%) caused by pneumococcus is responsible for invasive pneumococcal disease. Pneumococcal Conjugate Vaccine (PCV) has been introduced by the Government of India in a phased manner in selected states, but Haryana was not included. Objective: To draw key lessons learned from the process of newer vaccine introduction (PCV) in Haryana from the state’s resou...

S. K. Dalpath *, S. Trikha, M. Sharma, S. Juneja, M. Gupta, S. Kumar and A. P. Kumar

Public Health Policy and Planning, Monitoring & Evaluation, Haryana State Health Resource Centre, Panchkula, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.12(8).4519-24

4519-4524

4234

1343

40.

SUPPRESSION OF ELEVATED REACTIVE OXYGEN SPECIES BY ACORUS CALAMUS (VACHA) A SWEET FLAG IN DROSOPHILA MELANOGASTER UNDER STRESS FULL CONDITIONS

Reactive Oxygen Species is a phrase used to describe a number of reactive molecules and free radicals derived from molecular Oxygen. The production of Oxygen based radicals is the bane to all aerobic species where its excessive levels intern induces oxidative stress. The present study is to evaluate the anti-stress property of Acorus calamus (vacha), where the fruit flies in different groups are a...

Asra Fathima, H.B. Vasanth Patil and B.Y. Sathish Kumar*

Post Graduate Department of Studies and Research in Bio-technology, J.S.S. College of Arts, Commerce and Science (Autonomous college of University of Mysore), Ooty Road, Mysore 570 025, Karnataka, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1431-39

1431-1439

4233

1623

46.

FORMULATION, CHARACTERIZATION AND EVALUATION OF ISOTRETINOIN GEL FOR TREATMENT OF ACNE VULGARIS

Acne vulgaris is a commonly diagnosed inflammatory skin condition that affects pediatric, young and adult patients. The object of the paper is formulation development and evaluation of isotretinoin gel for the treatment of Acne vulgaris. The isotretinoin based anti-acne gel was formulated using different polymers includes carbopol 940, carbopol 934 and carbopol 980. Disodium edetate is used as ch...

S. Soni and A. Bharadwaj *

RKDF College of Pharmacy, SRK University, Misrod, Bhopal, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(2).873-83

873-883

4233

1615

44.

SYNTHESIS, CHARACTERIZATION OF SOME 2-AZETIDINONE DERIVATIVES FROM 4- NITRO ETHYL BENZOATE BY MICROWAVE METHOD AND EVALUATION OF THEIR ANTIMICROBIAL ACTIVITY

Non classical, High-speed, environmentally benign synthesis with microwaves has attracted researchers for organic synthesis a considerable amount of attention in recent years. An expeditious one pot microwave irradiation method for preparation of 2-azetidinones is developed. This method has been assessed as greener methodology. In our present study, series of five novel azetidinones  are synthesi...

S.K. Gawande* and R.E. Khadsan

Department of Applied Science and Humanities, Mauli College of Engineering and Technology, Shegaon – 444 203 Dist – Buldana, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2966-71

2966-2971

4232

4520

15.

NOCTURNAL ENURESIS, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF PANDANUS ODORATISSIMUS L. PEDUNCLE

Nocturnal Enuresis treatment activity in rabbits by measuring the changes in urine volume and concentrations of electrolytes as well as bladder capacities. In addition, antioxidant activity was measured using free radical scavenging (DPPH method) and antimicrobial activity against human bacterial pathogens using agar diffusion technique. Pandanus Odoratissimus L. peduncle showed no toxic effect wi...

Amina El-Shaibany

Department of Pharmacognosy, Faculty of Pharmacy, University of Sana’a, Sana’a, Yemen

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(3).811-18

811-818

4231

2037

44.

PROTECTIVE EFFECT OF “RAPHANUS SATIVUS” EXTRACT AGAINST COPPER SULPHATE TOXICITY IN “CTENOPHARYNGODON IDELLA” FISH

The living organisms of the aquatic ecosystem have been directly affected by the accumulation of the heavy metals in the aquatic environment 1. Fishes are very good biosensors of aquatic contaminants and as bio-indicator species respond with great sensitivity to changes in the aquatic environment. Copper will accumulate in many different organs in fish and mollusks. In the present study the acute ...

S. Celine Hilda Mary *, D. Bhuvaneswari and R. Anandan

PG and Research Department of Biochemistry, St. Joseph’s college of Arts & Science, Cuddalore, Tamilnadu, India

DOI: 10.13040/IJPSR.0975-8232.7(6).2620-24

2620-24

4231

1783

24.

DEVELOPMENT AND VALIDATION OF BIO-ANALYTICAL RP-ULTRA FAST LIQUID CHROMATOGRAPHIC METHOD FOR SIMULTANEOUS ESTIMATION OF CLOPIDOGREL AND ROSUVASTATIN IN HUMAN PLASMA

ABSTRACT: This manuscript describes a simple, sensitive, rapid and precise Ultra fast liquid chromatographic (UFLC) method was developed and validated for the simultaneous determination Clopidogrel and Rosuvastatin in human plasma according to USFDA draft guidelines. In the current study, the analysis was performed on phenomenex C8 (250 × 4.6mm, 5μm) column using phosphate buffer (pH-2.5) and ac...

Jinesh Bahubali Nagavi *and Bannimath Gurupadayya

Department of Pharmaceutical Analysis, JSS College of Pharmacy, JSS University, Mysore 570015, Karnataka, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(1).219-25

219-225

4230

1591

23.

DESIGN AND EVALUATION OF BILAYERED MUCOADHESIVE FILM OF CEFPODOXIME PROXETIL

The objective of the present work was to formulate and evaluate a sustained release gastroretentive dosage form. A mucoadhesive bilayered film was prepared consisting of an Immediate Release (IR) and a Controlled Release (CR) layer. The film is folded into a Hard Gelatin Capsule which after administration into GIT unfolds and adheres to the GI mucosa. Cefpodoxime Proxetil is an antibiotic of BCS C...

N. Banerjee and S.R. Singh

Dr. L.H. Hiranandani College of Pharmacy, Ulhasnagar-03, Mumbai, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1295-02

1295-1302

4230

1802

70.

PHARMACOLOGICAL AND PHYTOCHEMICAL EVALUATION OF ANTI-ULCEROGENIC POTENTIAL OF SOLANUM NIGRUM

Anti-ulcer activity of the Solanum nigrum     L. extracts was studied in rats by using pylorus ligated ulcer model. Rantidine was used as the standard drug for comparison. The animals were sacrificed after 19 hrs after the ligation. Stomach was dissected out and contents were drained into tubes and were centrifuged at 1000 rpm for 10min and volume was noted. The PH of gastric juice was recorde...

G.G. Kavitha Shree*, S. Parvathi , P.S.S. Ramkumar , S. Shanmuga Priya

Senior Research Fellow, Department of Home Science Extension, Home Science College and Research Institute, Tamil Nadu Agricultural University, Madurai- 625 104, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(8).2837-40

2837-2840

4230

1594

8.

EVALUATION OF ANALGESIC ACTIVITY OF MOMORDICA DIOICA ROXB. WILLD FRUIT PULP

In the present study Momordica dioica Roxb willd (Cucurbitaceae) fruit pulp was successively extracted with petroleum ether, ethyl acetate and methanol. All extracts were vacuum dried to yield the respective extracts. All extracts were evaluated by non-narcotic models like acetic acid induced writhing syndrome test and narcotic models like hot plate for its analgesic activity in doses of 50 mg/kg ...

M. S. Rakh *, S. R. Chaudhari

Department of Pharmacognosy, Amrutvahini College of Pharmacy, Sangamner, Dist. Ahmednagar, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(9-S).53-56

53-56

4230

1550