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PREPARATION AND EVALUATION OF HPMC-ALGINATE MUCOADHESIVE MICROCAPSULES OF DICLOFENAC FOR CONTROLLED RELEASE
A new, novel promising technology for obtaining controlled release and enhancing the bioavailability is a combination of mucoadhesion principle and microencapsulation to result in mucoadhesive microcapsules. Mucoadhesive microcapsules consist of either entirely of a mucoadhesive polymer or having an outer coating enclosing the drug particles. They facilitate an intimate and prolonged contact with ...
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EVALUATION OF ANTHELMINTIC ACTIVITY OF DALBERGIA SISSOO ROXB.
The ethanolic extract of bark of Dalbergia sissoo Roxb. was investigated for its activity against Indian earthworms Pheretima posthuma and nematode Ascardi galli. Various concentrations (10, 20, 50 mg/ml) of ethanolic extract were tested, which involved determination of time of paralysis and time of death of the worms. It was compared with Piperazine citrate (15 mg/ml) and Albendazole (20 mg/ml) a...
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THE IMPACT OF FOOT REFLEXOLOGY MASSAGE ON ANXIETY CAUSED BY BLOOD TRANSFUSION IN CHILDREN WITH THALASSEMIA
Introduction: Based on the results of formerly conducted studies, the application of invasive methods, such as blood transfusion, for the treatment of children with thalassemia cause distress and anxiety symptoms in these children; therefore, it is attempted to apply non-invasive, non-pharmacological, simple, and inexpensive nursing practice to improve these deficiencies. Thus, the present study w...
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COMPARISON OF SURGICAL SITE INFECTION RATE BETWEEN ANTIBACTERIAL COATED SURGICAL SUTURE AND CONVENTIONAL SUTURE: A RANDOMIZED CONTROLLED SINGLE CENTRE STUDY FOR PREVENTIVE MEASURE OF POSTOPERATIVE INFECTION
The main objective of this study is to compare the reduction rate of surgical site infection (SSI) between Triclosan coated (TC) and conventional surgical (CS) suture postoperatively. Surgical site infection (SSI) can be presented as a major challenge for people in the sense of mortality and morbidity mostly in developing countries. The result of SSI with antibacterial suture in developed countrie...
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IN-VITRO EVALUATION OF ANTIBACTERIAL ACTIVITY AND CYTOTOXICITY EFFECT OF CHEMICALLY SYNTHESIZED ZnO NANOPARTICLE
Nanoparticles, generally considered as particle with a size of upto 100nm, exhibit completely new or improved properties as compared to the larger particles of the bulk material that they are composed of based on specific characteristics such as size, distribution and morphology. In this study ZnO nanoparticle was synthesized by a simple and easy chemical method from ZnCl2. The synthesized nanopar...
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ANTIBACTERIAL ACTIVITIES AND BRINE SHRIMP LETHALITY BIOASSAY OF THE CHLOROFORM EXTRACT OF STEM BARK OF CRATAEVA NURVALA BUCH HAM
Antibacterial and cytotoxic activities of the chloroform extract of the stem bark of Crataeva nurvala (Bengali name- Borun; Family- Capparidaceae) were studied. Antibacterial activity was determined against two Gram positive (Bacillus cereus, Bacillus megaterium,) and four Gram negative (Escherichia coli, Shigella dysenteriae, Shigella sonnei, Shigella boydii) human pathogenic bacteria by disc d...
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EFFECT OF GARLIC ADMINISTRATION ON RAT HEART MITOCHONDRIAL ENZYMES AFTER NOISE STRESS EXPOSURE
Background: Noise has been recognized as one of the risk factors for cardiovascular diseases. Garlic is one of the oldest medications used in human culture. Garlic is used in herbal medicine for thousands of years and also as one of the main food ingredient. The present study was aimed to investigate the cardioprotective effect of garlic after noise exposure in Wistar albino rats. Methods: Anim...
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DIURETIC ACTIVITY OF METHANOLIC RHIZOME EXTRACT OF PICRORRHIZA KURROA ROYLE EX. BENTH.
Kidneys are the excretory organs of our body that serves the important functions such as elimination of waste products, regulation of fluid volume and electrolyte content of the extracellular fluid. Picrorrhiza kurroa (Scrophulariaceae) is a small perennial herb growing in the hilly parts of the north-Western Himalayas region in India and Nepal. The objective of the present study was to evaluate a...
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COMPARITIVE EFFECTS OF HORMONAL AND NON HORMONAL CONTRACEPTIVES ON FASTING BLOOD SUGAR LEVELS
The objective of the current study was to differentiate contraceptives for their effects on carbohydrate metabolism. This is a cross sectional design that was conducted in different clinical settings of urban population who belong to low socio economic status by convenience sampling method. Females representing fertile age ranging from 26 to 32 and maintained on different types of hormonal and non...
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PHYSICAL, CHEMICAL AND PHYSICO-CHEMICAL CONTROL OF HELIOTROPIUM INDICUM LINN., BORAGINACEAE, POWDER AND TINCTURE
The quality control of herbal drugs and their extracts is essential when they are used as raw material for the development of herbal medicines. In this work, several techniques (pharmacopoeial and non-pharmacopoeial) were performed, aiming at establishing quality control parameters of the leaves of Heliotropium indicum L. (Boraginaceae), a shrub popularly known as stinker (fedegoso) in Brazilian n...
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