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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

IJPSR is indexed with Embase

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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12.

PLANT REGENERATION FROM THE NODAL PART OF CITRULLUS COLOCYNTHIS (L.) SCHARD.

Citrullus colocynthis, belonging to the family of cucurbitaceae. It is a xerophytic desert plant, widely used for its medicinal purpose. In tribal areas it is used for the treatment of constipation, oedema, bacterial infection, cancer, diabetes and abortifacient. Present study is based on developing a protocol for plantlet regeneration from the nodal segment. The sterilized explants were inoculate...

Anu Shrivastava and Shikha Roy*

Plant Biotech Laboratory, Department of Botany, University of Rajasthan, Jaipur, Rajasthan, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(11).2825-27

2825-2827

2514

1002

6

22.

THE IN-VIVO EFFECTS OF PARTIALLY PURIFIED SUB-FRACTION (TAF2) OF THE CRUDE METHANOLIC EXTRACT OF EURYCOMA LONGIFOLIA ROOTS ON THE HAEMATOLOGICAL, BIOCHEMICAL AND HISTOLOGY PARAMETERS

Eurycoma longifolia (E. longifolia) Jack has been widely used in traditional medicine for its antimalarial, aphrodisiac, anti-diabetic, antimicrobial, anti-pyretic and anticancer activities. As yet, no study has been done on biosafety of partially purified sub-fraction (TAF2) of the crude methanolic extract of E. longifolia roots. This study aims to evaluate, in vivo, the effects of TAF2 on the ha...

Omar Saeed Ali Al-Salahi , Abdel-Hamid Zaki ,Kit-Lam Chan , Amin Malik Shah , Wan Zaidah Abdullah , Narazah Mohd Yusoff*

MBBS (Malaya), DCP (London), M Med Sc (London), PhD (Kobe), Associate Professor and Hematologist, Advanced Medical and Dental Institutem, Universiti Sains Malaysia, No 6 (Lot 13), Persiaran Seksyen 4/9, Bandar Putra Bertam, 13200 Kepala Batas, Pulau Pinang, Malaysia

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3101-05

3101-3105

2512

989

3

28.

ORTHOSIPHON STAMINEUS INCREASES METABOLISM OF AMINOPYRINE IN FEMALE RAT HEPATOCYTES BY INHIBITING PROTEIN KINASE- A

Orthosiphon stamineus (Family: Lamiaceae) has becoming one of the popular medicinal plants in Malaysia due to its high beneficial effects in treating diabetes mellitus, hypertension and kidney stones. The present study was conducted to evaluate the mechanism of O. stamineus in affecting metabolism of aminopyrine in female rat hepatocytes via second messenger pathway. Liver perfusion was used to is...

Jin Han Chin and Abas Haji Hussin

Senior Lecturer, Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, UCSI University 1, No.1, Jalan Menara Gading, 56000, Kuala Lumpur, Malaysia

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(7).1777-80

1777-1780

2512

899

1

86.

ANTI-GLYCATION EFFECT OF WHITTON ROOT (EULOPHIA NUDA) IN-VITRO CONDITION

Non enzymatic glycation takes place when elevated levels of reduced sugars react with amino groups of proteins and is called as advanced glycation end products (AGEs) are responsible for Diabetes Mellitus. Hydroalcoholic extract of Whitton root (Eulophia nuda) was tested for in-vitro inhibition of non-enzymatic glycation of Immunoglobin G.  Plant extracts have their own importance and now being s...

Dinesh Prasad Yadav*, Ram Charan Chhipa and Balvinder Singh

Department of Biochemistry, Suresh Gyan Vihar University, Mahal Jagatpura, Jaipur, Rajasthan, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3502-06

3502-3506

2511

1177

5

7.

PHARMACEUTICAL SCIENCE BRINGS GENETICS AND IMMUNOLOGY TOGETHER TO EVOLVE A NEW DIMENSION IN TREATING CHILDHOOD CANCER: A REVIEW

Surgery, chemotherapy and radiation therapy has been the cornerstone of cancer management for decades. Since a decade or so, targeted therapies by way of Imatinib and Trastuzumab arrived that specifically target cancer cells and reply on specific molecular changes to identify them. These are in fact the standard treatment at present in several forms of cancer. But now in recent times, the fifth pi...

A. S. Singh* and M. Y. Tilawat

SVKM’S Narsee Monjee Institute of Management Studies, Babulde, Bank of Tapi River, Mumbai-Agra Road, Shirpur, Maharashtra, India

DOI: 10.13040/IJPSR.0975-8232.8(6).2396-01

2396-2401

2511

893

0

29.

SYNTHESIS NEW MOLECULARLY IMPRINTED POLYMERS FOR THE SELECTIVE ELECTRODES OF ISOPROPAMIDE FROM PHARMACEUTICAL SAMPLES

Liquid electrodes of polymers imprinted with Isopropamide (ISP) were synthesized based on precipitation polymerization mechanism. The molecularly imprinted polymer (MIP) and non-imprinted polymers (NIP) were synthesized using (ISP) as a template. In the polymerization process, 2-Hydroxyethyl meth acrylate (2-HEMA) and 2-Vinyl pyridine (2-VP) were used as monomers. Di-vinylbanzene (DVB) was used as...

A. M. Dhari * and Y. K. Al-Bayati

Department of Chemistry, College of Science, University of Baghdad, Al-Jadryia, Baghdad, Iraq.

DOI: 10.13040/IJPSR.0975-8232.10(6).2870-78

2870-2878

2511

832

0

03.

NATURAL GELLING AGENTS POLYMER IN PHARMACEUTICAL PREPARATION

Pharmaceutical preparation mostly contains active ingredients and excipients. The function of excipients to improve the physicochemical properties of pharmaceutical manufacturing products. In pharmaceutical preparation, polymer plays a key role act as excipients in any dosage formulation development. Polymers are derived from the source of natural and synthetic. The polymer should have basic prope...

Muhammad Masood Ahmad and Syed Nasir Abbas Bukhari

Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.

DOI: 10.13040/IJPSR.0975-8232.12(12).6139-50

6139-6150

2511

759

0

61.

SYNTHESIS AND BIOLOGICAL EVALUATION OF COUMARIN CLUBBED OXAZINES

Coumarin segment have been reported broad spectrum of different biological activities with the oxazine derivatives. In view that we have synthesized newer coumarin clubbed 4-(4-fluorophenyl)-6-substituted phenyl-2H-1,3-oxazin-2-amine and screened for their biological studies. 4-(4-fluorophenyl)-6-substituted phenyl-2H-1,3-oxazin-2-amine IIa-j condensed with 4-Methyl-6-nitro-2-oxo-2H-chromen-7-yl c...

N. B. Chauhan, N. B. Patel * and B. M. Mistry

Department of Chemistry, Veer Narmad South Gujarat University, Surat, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.9(6).2595-03

2595-2603

2510

1223

1

52.

ASSESSMENT OF ANALGESIC AND ANTIDIARRHOEAL ACTIVITIES OF DIFFERENT FRACTIONS OF CRUDE EXTRACT OF STEPHANIA JAPONICA STEM

The different fractions of crude methanol extract of stem of Stephania japonica (Thunb.) Miers (Menispermaceae) was screened for its analgesic and antidiarrhoeal activities. The different fractions of crude extract produced significant writhing inhibition in acetic acid induced writhing in mice at the dose of 250 and 500 mg/kg body weight comparable to the standard drug diclofenac sodium at the do...

Bishwajit Bokshi, S.M. Abdur Rahman*, Samir Kumar Sadhu, Ashif Muhammad and Md. Ariful Islam

Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(3).1233-38

1233-1238

2509

969

6

24.

SCHIZOPHRENIA: A LOOK FORWARD WITH ZINC06025953

Phosphodiesterase PDE10A is an enzyme that has established connection earlier with schizophrenic condition, schizophrenia is well known severely chronic and disabling disease worldwide today. Unfortunately, there is no concrete evidence till day to point out as a single cause of this disease. However, in a recent work a research team of Merck Research Group recognized earlier pyp-1 as an effective...

Rituraj * and K. K. Srivastava

Department of Chemistry, Vinoba Bhave University, Hazaribag, Jharkhand, India.

DOI: 10.13040/IJPSR.0975-8232.8(5).2122-33

2122-2133

2509

899

0