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EFFECT OF COMBINED VITAMIN E SUPPLEMENTATION AND TREADMILL EXERCISE ON SPECIFIC HAEMATOLOGICAL PARAMETERS OF THE SEDENTARY UNIVERSITY STUDENTS
Background: Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the rest of the body (i.e. the tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power the functions of the organism in the process called metabolism. Several research studies have pointed out the role of vitamin supplementation and amelioration from exercise i...
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HAEMATOLOGICAL AMELIORATION BY ZIZYPHUS MAURITIANA IN SILICA INDUCED TOXICITY IN WISTAR ALBINO RATS
This study was aimed to investigate the biochemical influence of aqueous extracts of roots, stem and leaves of Zizyphus mauritiana (ZM) on silica induced toxicity in rats, with changes in inflammatory markers in liver and kidney. To test the preventive effect of extracts of Zizyphus mauritiana on development of silica induced toxicity in wistar albino rats, animals were treated simultaneously with...
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HEPATOPROTECTIVE ACTIVITY OF SACHHARUM OFFICINARUM AGAINST PARACETAMOL INDUCED HEPATOTOXICITY IN RATS
The hepatoprotective activity of juice of Saccharum officinarum was investigated against paracetamol (acetaminophen) induced liver damage in rats. Paracetamol (PCM) is analgesic, antipyretics drugs available as an over the counter (OTC) medication which cause hepatotoxicity as higher doses. Paracetamol at 3gm/kg induced liver damage in rats manifested by statically increased serum alanine aminotra...
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SYNTHESIS OF THIAZOLIDINONE AND AZETIDINONE DERIVATIVES OF BENZOXAZOLINONE AS ANTIMICROBIAL AGENTS
The present investigation is concerned with synthesis of new substituted benzoxazolinone derivatives (1-18) with the objective of discovering novel and potent antimicrobial agents. The structure of all the synthesized compounds were elucidated by elemental (C, H, N) and spectral (IR, 1HNMR and mass) analysis. The purity of the synthesized compounds was checked by thin layer chromatography (TLC). T...
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DETERMINATION OF RIZATRIPTAN IN BULK AND ITS TABLET DOSAGE FORMS BY UV SPECTROSCOPIC METHOD.
Rizatriptan is a selective 5-HT1B/1D agonist which is used in the treatment of migraine headaches. Zero order spectroscopic method has been developed for the determination of rizatriptan. Rizatriptan in its 0.1 N HCl solutions was determined at the wavelength ranges of 220–400 nm by the spectroscopic method. Rizatriptan showed an absorption peak at 226 nm. Linearity ranges were found as 1-5 µg/...
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ELECTROCHEMICAL BEHAVIOR OF MANIDIPINE AND ITS VOLTAMMETRIC DETERMINATION IN PHARMACEUTICAL FORMULATIONS
The electrochemical behavior of Manidipine is studied by employing cyclic voltammetry (CV) and Differential Pulse Polaro graphy (DPP) in universal buffers of PH ranging from 2.0 to 12.0. The kinetic parameters, such as transfer co-efficient, diffusion co-efficient, and heterogeneous forward rate constant values are evaluated by employing these techniques. Differential Pulse Polarography is emp...
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ANTI- CONVULSANT PROFILE OF AQUEOUS EXTRACT OF SAPINDUS LAURIFOLIA IN EXPERIMENTAL ANIMALS
Objective: The aim of the present study was to evaluatethe anti convulsant property of aqueous extract of Sapindus laurifolia in Pentylenetetrazole (PTZ) and MES induced convulsions in experimental models. Materials & Methods: The purpose of this study is to explore the anticonvulsant activity of ethanolic extract of Momordica tuberosa using Pentylenetetrazole and maximal electric shock induce...
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FORMULATION AND OPTIMIZATION OF FAST DISSOLVING TABLETS OF OLANZAPINE USING VACUUM DRYING TECHNIQUE BY 22 FACTORIAL DESIGN
The purpose of this research was to develop fast dissolving tablets of olanzapine and to optimize the processing variables. Tablets containing olanzapine, camphor, crosscarmellose, and directly compressible lactose were prepared by direct compression technique. The tablets were compressed and later exposed to vacuum. Sublimation of camphor from tablets resulted in superior fast dissolving tablets....
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IN VITRO CYTOTOXIC, ANTIOXIDANT AND GC-MS STUDY OF LEAF EXTRACTS OF CLERODENDRUM PHLOMIDIS
Clerodendrum phlomidis is a shrub common in India and Sri Lanka. It is one of the highly traded medicinal plants from tropical forests, as the leaves and roots are used in folk-lore, Ayurveda, Siddha and Unnani medicines. In this study preliminary phytochemical screening, cytotoxic, antioxidant and GC - MS study of leaf of C. phlomidis was evaluated. Successive extraction of the leaf of C. phlomid...
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EFFECT OF HUMIC AND SALICYLIC ACIDS ON OIL YIELD AND FLAVONOID GLYCOSIDE OF SAFFLOWERS (CARTHAMUS TINCTORIUS L.) AS MEDICINAL PLANTS GROWN IN IRAQ
This study was conducted to investigation the effect of humic acid and salicylic on oil yield and flavonoids glycoside of safflower plant (Carthamus tinctorius L.) grown in Iraq. After soil preparation the plant seeds were cultivated during winter growing seeds at 2015-2017 at Karbala region, South Baghdad in Iraq. The humic acid was applied at 1000, 2000 and 4000 mg/lit conception as organic flow...
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