Most Popular
IN VITRO CYTOTOXIC EFFECT OF METHANOLIC CRUDE EXTRACTS OF OCIMUM SANCTUM
The aim of this research is to observe the cytotoxic activities of methanolic crude extracts of Ocimum sanctum (Family: Lamiaceae). The leaves of Ocimum sanctum was extracted with organic solvent (methanol) and the extracts were fractionated by using solvent-solvent partition. The n-hexane, ethyl acetate, and chloroform soluble fractions of methanolic crude extract of Ocimum sanctum were screened ...
3907
1731
CONTROLLED RELEASE OF AN ANTI- EMETIC AGENT FROM A POLYMERIC MATRIX: FORMULATION AND IN- VITRO STUDY
The objective of the present study was to develop once daily controlled-release matrix tablets of Domperidone Maleate, an anti- emetic agent. Several formulations containing an anti- emetic agent (domperidone maleate) and hydrophilic polymers (Hydroxypropyl methylcellulose, Carbopol and Polyethylene oxide) were prepared by wet granulation methods. The tablets were subjected to thickness, diameter,...
3907
2028
SCREENING OF BEHAVIOURAL, MUSCLE CO-ORDINATION & ANXIOLYTIC ACTIVITIES OF METHANOLIC EXTRACT OF SOPHORA INTERRUPTA (BEDD)
The aim of this study was to evaluate the behavioural, muscle coordination and anxiolytic activities of methanolic extracts of Sophora interrupta (papilionaceae) in mice. The behavioural, muscle coordination and anxiolytic activities were evaluated by using various models of CNS using mice. Diazepam was used as standard drug for muscle coordination and anxiolytic studies. The extracts were adminis...
3906
1530
EVALUATION OF THE IMMUNOMODULATORY ACTIVITY OF THE ROOTS OF ICHNOCARPUS FRUTESCENS
The objective of the present study was to investigate the immunomodulatory activity of the roots of Ichnocarpus frutescents R.Br. In the present study Pet. Ether, Chloroform and Methanolic fractions of the ethanolic extract of the roots of Ichnocarpus frutescens, in the doses of 10mg/kg and 30mg/kg, were administered orally to evaluate the immunomodulatory activity. The Methanolic fraction in the ...
3905
1526
IDENTIFICATION OF HEAVY METAL TOXICITY INDUCED BIOMARKERS AND THE PROTECTIVE ROLE OF ASCORBIC ACID SUPPLEMENTATION IN CHANNA PUNCTATUS
Arsenic and mercury are presently the most common pollutants of freshwater bodies. There is a continuous increase in the toxic level of these pollutants with some seasonal changes, affecting the aquatic biota. The present study aimed to identify cellular biomarkers of arsenic and mercury toxicity in freshwater fish Channa punctatus. Antioxidant defense like catalase (CAT), superoxide dismutase (SO...
3905
1571
INCIDENCE AND COMPARATIVE ANALYSIS OF ADVERSE DRUG REACTIONS IN DOTS
To assess the adverse drug reactions (ADRs) induced by antitubercular drugs used in Directly Observed Treatment Short Course (DOTS) from previously reported 8 articles from referred sources. Articles related to adverse drug reactions induced by first line anti- tuberculosis drugs in DOTS therapy published during 2002 to 2012 were searched. The incidence rate of each type of ADR from entire ADRs we...
3904
1482
ISOLATION AND CHARACTERISATION OF A NEW ALLELOCHEMICAL FROM PARTHENIUM HYSTEROPHORUS L.
Parthenium hysterophorus L. is commonly known as “Gajar ghas" in Hindi and belongs to family Composite. It is an annual herb erect up to 1.5 m in hight. Its stems is branched and covered with trichomes. Its leaves are pale green, branched and covered with soft fine hairs. In Homoeopathy system, allergies caused by Parthenium can be treated by a drug prepared from Parthenium. Root decoction ...
3903
2127
IN- VITRO ANTIOXIDANT ACTIVITY OF HYDROETHANOLIC EXTRACT OF STEM BARK OF OUGEINIA OOJEINENSIS (ROXB.) HOCHR (LEGUMINOSAE)
Safer antioxidants suitable for long term use are needed to prevent or stop the progression of free radical mediated disorders. In this study, the antioxidant activity of hydroethanolic extract of stem bark of Ougeinia oojeinensis (Roxb.) (HEBO) was studied using various in vitro assays. The antioxidant activity of the extract was evaluated by using the free radical scavenging activity assay (DPPH...
3903
1696
EFFECT OF ETANERCEPT AGAINST MYOCARDIAL ISCHEMIA/REPERFUSION INJURY IN MALE MICE
Objective: This study was undertaken to investigate the potential role of etanercept in amelioration of myocardial I/R injury induced by ligation of coronary artery in a mice model. Materials & methods: Adult male Swiss Albino mice were randomized into 4 equal groups. Group (1) sham group: mice underwent the same anesthetic and surgical procedure as the control group except ligation of LAD cor...
3902
1494
DETECTION OF ANTI-QUORUM SENSING ACTIVITY OF ROSEMARINUS OFFICINALIS AND VALERIANA OFFICINALIS USING MICROBIAL BIOSENSOR STRAIN
Quorum-sensing is a phenomenon in which bacteria exhibit several density dependent phenotypes. Quorum-sensing is achieved through production of auto - inducer which on acquiring a threshold concentration, activates the genes, bringing into effect the concerned phenotypes. Ayurvedic medicinal plant extracts are being used to treat a plethora of infectious disease and are known to be rich in phytoch...
3902
1683