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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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13.

FORMULATION AND EVALUATION OF MUCOADHESIVE GEL FOR ORAL CANDIDIASIS

Oral candidiasis (OC) is a common fungal infection characterized by white patches on the oral mucosa, often triggered by factors like immunosuppression and medication use. It can affect anyone, regardless of age or background. The formulation of mucoadhesive gels for the treatment of oral candidiasis is a promising area of research. The gel enhances the residence time of the drug at the site of in...

Nematullah and Richa Srivastava *

Amity Institute of Pharmacy, Amity University Noida, Sector 125, Noida, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.16(4).953-61

953-961

2243

1240

10.

SIMULTANEOUS DETERMINATION OF PREDNISOLONE AND ASPIRIN IN SYNTHETIC MIXTURE BY VIERORDT´s METHOD

Prednisolone (10mg/day) plus low dose Aspirin (80mg/day) improve the implantation rate in women with autoimmune condition who are undergoing in-vitro fertilization. A new, simple, precise, accurate, and validated simultaneous equation method (Vierordt´s Method) has been developed for simultaneous determination of Prednisolone and Aspirin in the synthetic mixture. The method was based on the measu...

P. Patel *, J. Patel and K. Detholia

Department of Pharmaceutical Quality Assurance, Smt. S.M. Shah Pharmacy College, Amsaran, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.12(5).2620-27

2620-2627

2243

1587

43.

FORMULATION AND EVALUATION OF SUSTAIN RELEASE MATRIX TABLET OF FLUVOXAMINE MALEATE USING MORINGA OLEIFERA GUM

Fluvoxamine Maleate, an oral serotonin reuptake inhibitor, has been used widely for the treatment of anxiety. Sustained-release matrix-type drug delivery system has advantages over conventional modes of drug administration, enhancing drug bioavailability as it avoids the first-pass metabolism and improves patient compliance. Optimization of the formulation was performed by varying the concentratio...

P. D. Deore, S. A. Katti * and S. S. Sonawane

Department of Pharmaceutical Quality Assurance, Mahatma Gandhi Vidyamandir’s Pharmacy College, Nashik, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.12(7).3879-86

3879-3886

2243

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24.

EVALUATION OF COGNITION ENHANCING ACTIVITY OF SESBANIA GRANDIFLORA (L.) FRUITS EXTRACT ON HIGH FAT DIET INDUCED DEMENTIA

The study was aimed to justify the traditional claim of fruits of Sesbania grandiflora (Leguminosae) as a medhya rasayana. Dementia was induced with chronic administration of a high fat diet for 90 days. Petroleum ether, benzene, chloroform, acetone, ethanol extracts of fruits of Sesbania grandiflora were evaluated for cognition-enhancing activity in high-fat diet-induced dementia in rats using an...

V. J. Mahadik * and K. A. Wadkar

Shree Santkrupa Shikshan Sanstha’s College of Pharmacy (D. Pharm), Ghogaon, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.11(11).5547-52

5547-5552

2242

1168

28.

FORMULATION AND EVALUATION OF MUCOADHESIVE MICROSPHERES OF CIMETIDINE FOR ITS GASTRO RETENTIVE DRUG DELIVERY EFFICACY

The Aim and objective of this work were to build up a gastro retentive drug delivery system. Cimetidine is used as a model drug for making mucoadhesive dosage forms. The formulation can be achieved by using the ionic gelation method. The model drug used in this work plan is categorized in antiulcer treatment. The extended-release mucoadhesive microspheres of the drug provide constant plasma concen...

K. M. Nidhi *, Sanjar Alam, K. M. Uma, Naveen Sharma, Jaya Bhati and Sarita Prajapati

Department of Pharmacy, J. K. Institute of Pharmacy, Bulandshahar, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.13(4).1688-94

1688-1694

2242

1210

19.

SYNTHESIS, CHARACTERIZATION, MOLECULAR DOCKING STUDIES AND ANTHELMINTIC AND ANTI-CANCER ACTIVITY OF PYRAZOLE CONTAIN NOVEL INDOLIN-2-ONE DERIVATIVES

Background: Imidazole-5-one scaffold has been predicted in the important synthetic drug analogs, which gave valuable information for treatment and high binding affinity to the multiple receptors helpful drug development. Objective: To synthesize and evaluate the anthelmintic, anticancer, and Insilco docking studies of pyrazole contain novel Indole derivatives (4a-4h). Methods: In the present work,...

Hemalatha Sattu *, Sayeda Hinanaaz and Oleti Navneetha

Department of Pharmaceutical Chemistry, S. N. Vanita Pharmacy Mahavidyalaya, Tarnaka, Secunderabad, Hyderabad, India.

DOI: 10.13040/IJPSR.0975-8232.14(7).3404-13

3404-3413

2242

1156

5.

ETHNOMEDICINAL AND PHARMACOLOGICAL IMPORTANCE OF BACOPA MONNIERI: A REVIEW

Despite the considerable advancement in medical sciences and allopathic medicines, the use of complementary and alternative medicines has dramatically increased worldwide. Bacopa monnieri is one of the most important and highly studied medicinal plants that is being used as an ayurvedic or ethnomedicine for thousands of years. It improves intelligence rejuvenation and treats mental illness, fever,...

S. Das * and J. C. Kalita

Animal Physiology and Biochemistry Laboratory, Department of Zoology, Gauhati University, Guwahati, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.14(7).3255-63

3255-3263

2241

1534

41.

SCREENING OF POLYHERBAL PLANT EXTRACTS AGAINST CARBOPLATIN INDUCED THROMBOCYTOPENIA IN MICE

Thrombocytopenia, a condition in which platelet count decreases (<150-450 × 109/L), occurs as a result of clinical conditions such as viral infections or cancer or as a side effect of chemotherapy or it can be inherited, but if not treated on time it can be life threaten-ing. So, here we have evaluated the anti-thrombocytopenic potential of three plant extracts (aqueous extracts of Carica papa...

V. B. Thacker * and M. A. Rachchh

Department of Pharmaceutical Sciences, Gujarat Technological University (GTU), Ahmedabad, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.12(1).395-02

395-402

2241

1218

24.

BIOACTIVE COMPOUNDS FROM MARINE INVERTEBRATES AND THEIR PHARMACEUTICAL POTENTIAL

Marine environment is an exceptional storehouse of novel bioactive natural products that are mainly found in invertebrates such as sponges, arthropods, annelids, molluscs, etc. This diversity has been the source of unique chemical compounds. A large portion of these natural compounds has been extracted from marine invertebrates. Marine invertebrates are rich sources of bioactive compounds and thei...

V. Priya Senan * and M. Karthika

Post Graduate Department of Biotechnology, SAS SNDP Yogam College, Konni, Pathanamthitta, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.13(2).739-46

739-746

2240

1495

60.

THE POTENTIAL ROLE OF NANOTECHNOLOGY TO CONTROL OF INDUSTRIAL BIOFILM

In recent years, most researchers and interesting ones in the field of microbial biofilm documented that nanoparticles like silver, metal ions play a significant role in the biofilm approach. Here i would like to draw your attention to the modern technique in biofilm and the role of nanotechnology in combating medical resistant microbial infection. It is now realized that most bacterially derived ...

C. Patel * and N. Tripathi

Department of Microbiology, Sri Satya Sai University of Technology and Medical Science (SSSUTMS), Sehore, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(11).5831-43

5831-5843

2240

1121