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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

Inclusion in Web of Science (Thomson Reuters) - ESCI
Projected Impact Factor (2017): 0.59 , SJR (2017): 0.14
Five-Year Projected Impact Factor: 1.83

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Volume 5 (2014) - Issue 7, July

Review Articles

 
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1.

SALIVA-THE KEY REGULATOR OF ORAL CHANGES IN DIABETES PATIENTS

Saliva plays the most important role in the maintenance and preservation of the health of our oral cavity. In diabetes mellitus functions of salivary glands are impaired and as a consequence xerostomia develops. Hoposalivation leads to various oral mucosa alterations, ulcerations, taste alterations, burning mouth, dental decay, halitosis and various infections. All these alterations can compromise...

N. A. Babu, K. M. K. Masthan, T. Bhattacharjee and M. Elumalai*

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2579-83

2579-2583

3638

1203

2.

MENINGITIS CAUSED BY STREPTOCOCCUS PNEUMONIAE: A REVIEW

Meningitis is a condition whereby the protective membranes covering the central nervous system (or meninges) become inflamed. Infections of the central nervous system are still considered to be among the most debilitating diseases in the 21st century. The mortality from this infection ranges from 15% in industrialized to 40% in developing countries. Streptococcus Pneumoniae infections, including p...

Sawati Sharma*, Shubham Goyal, Narinder Pal Kaur and Akhilesh Vats

Department of Pharmacology, School of Pharmacy & Emerging Sciences, Baddi University of Emerging Sciences and Technology Makhnumajra, Baddi, Distt. Solan-173205, Himachal Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2584-95

2584-2595

1567

524

3.

FLOATING DRUG DELIVERY SYSTEM: A REVIEW

In the recent years, scientific and technological advancements have been made in the research and development of novel drug delivery systems by overcoming physiological troubles such as short gastric residence times and unpredictable gastric emptying times. Gastric emptying of dosage form is extremely variable process and ability to prolong and control the emptying time. Gastric transit time is va...

Vandana Tiwari*, Anurag Verma and Navneet Verma

Department of Pharmaceutics, Institute of Pharmaceutical Sciences and Research (IPSR), Sohramau, Unnao, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2596-05

2596-2605

2066

677

Research Articles

 
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4.

MIR AND NIR SPECTROSCOPY AS RAPID METHOD TO QUANTIFY MOLSIDOMIN IN GENERIC TABLET

This work investigates the potential of Partial Least Square (PLS) regression using two vibrational spectroscopies as mid infrared (MIR) and near infrared (NIR) spectroscopies for the quantification of molsidomin in tablets. Two very simple, rapid, inexpensive and green strategies were applied for this determination. Powder blends containing molsidomin and excipients were prepared. The excipients ...

C. Boyer , A. Boudis , Jp. Dubost* and K. Gaudin

Pharmaceutical and Analytical developments applied to neglected diseases and Counterfeits , EA 4575, University of Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux CEDEX, France

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2606-11

2606-2611

1050

951

5.

DEVELOPMENT OF pH-INDEPENDENT ACRYLIC-WAX MATRIX TYPE SUSTAINED RELEASE DRUG DELIVERY SYSTEM OF ACEBROPHYLLINE

The aim of the present study was to improve commercial twice-a-day Acebrophylline formulation to once-a-day new formulation to improve patient compliances. The double-layered tablet was composed of the fast release layer (Acebrophylline 50 mg) and sustained release layer (Acebrophylline 150 mg). To develop the double-layered tablet, the fast release and sustained release layers were prepared using...

Kim Kang Min , Ko Chan Young and Kang Jae Seon*

Department of Pharmacy , Kyungsung University, Busan, Republic of Korea

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2612-19

2612-2619

1272

1737

6.

STUDYING THE EFFECT OF DISPERSED DRUG CRYSTAL IN THE ORGANIC PHASE ON THE ENCAPSULATION BY SOLVENT EVAPORATION TECHNIQUE; (1) EFFECT OF DRUG LOADING EXTENT ON THE PRODUCT SIZE ANALYSIS, MORPHOLOGY AND DRUG CONTENT

Eudragit RS100 microcapsules containing Aspirin as a model drug was prepared using solvent evaporation technique. The drug was dispersed in the organic phase and poured into the aqueous phase with stirring until microcapsules formation. The product was collected by filtration and air dried. The particle size analysis of the products was done and normal distribution curve showed for the same size r...

Omar Mady

Department of Pharmaceutical Technology, Faculty of Pharmacy, Tanta University, Egypt

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2620-30

2620-2630

988

484

7.

APPLICABILITY OF BIVARIATE CALIBRATION ALGORITHM AND VIERORDT METHOD FOR SIMULTANEOUS DETERMINATION OF TIMOLOL MALEATE AND BRIMONIDINE TARTRATE IN THEIR BINARY MIXTURE AND PHARMACEUTICAL DOSAGE FORM

Three simple, rapid, sensitive, specific and economic spectrophotometric methods were developed and validated for simultaneous quantitation of timolol maleate (TM) and brimonidine tartarate (BT) in bulk powder and eye drops.  Vierordt’s and bivariate calibration algorithm spectrophotometric methods were developed for the simultaneous estimation of cited drugs in a binary mixture without previou...

Mohamed S. Rizk , Hanan A. Merey , Shereen M. Tawakkol and Mona N. Sweilam*

Faculty of Pharmacy, Helwan University , Ain Helwan, Cairo, Egypt

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5 (7). 2631-41

2631-2641

1165

433

8.

PROBIOTIC POTENTIALS OF LACTIC ACID BACTERIA ISOLATED FROM VAGINAL SWABS ON SELECTED GENITAL PATHOGENS

Eudragit RS100 microcapsules containing Aspirin as a model drug was prepared using solvent evaporation technique. The drug was dispersed in the organic phase and poured into the aqueous phase with stirring until microcapsules formation. The product was collected by filtration and air dried. The particle size analysis of the products was done and normal distribution curve showed for the same size r...

F.M. Agboola, B.A. Adeniyi*, C.A. Okolo, T.O. Ogunbanwo, F.A. Ayeni and T.O. Lawal

Department of Pharmaceutical Chemistry, M.G.V'S Pharmacy College, Department of Pharmaceutical Microbiology, Faculty of Pharmacy, University of Ibadan, Nigeria Department of Pharmaceutical Microbiology, Faculty of Pharmacy, University of Ibadan, Nigeria

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2642-50

2642-2650

1148

510

9.

DEVELOPMENT AND VALIDATION OF HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHIC (HPTLC) METHOD FOR ESTIMATION OF TAPENTADOL HYDROCHLORIDE IN BULK AND ITS TABLET DOSAGE FORM

A simple, accurate, rapid and sensitive high performance thin layer chromatographic method has been developed for the estimation of Tapentadol Hydrochloride in bulk and its tablet dosage form. Chromatographic separation of the drugs was performed on aluminum plates precoated with silica gel 60 F254 as the stationary phase and the solvent system consisted of methanol: toluene (4:1v/v). Densitometri...

Pragati Amin*, Manisha Tayde and Prakruti Amin

Department of Pharmaceutical Chemistry, M.G.V'S Pharmacy College, Panchavati, Nasik, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2651-56

2651-2656

1164

531

10.

SPECTROPHOTOMETRIC ANALYSIS OF BOVINE SERUM ALBUMIN IN PRESENCE OF 1-(4-AMINOPHENYL)-3-PHENYLPROP-2-EN-1-ONES

Proteins, which are soluble under normal physiological conditions, sometimes form insoluble aggregates with serious medical implications. Bovine serum albumin (BSA), a structural analogue of human serum albumin. Bovine Serum Albumin (BSA) has been used as a carrier, and stabilizing agent, for insoluble fatty acids. The chemistry of chalcone has been recognized as a significant field of study. An i...

S. Garg, M. Singh and N. Raghav*

Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2657-61

2657-2661

965

579

11.

IN SILICO EPITOPE PREDICTION AND HOMOLOGY MODELING OF ENVELOPE SURFACE GLYCOPROTEIN GP160, PRECURSOR REGION FROM HUMAN IMMUNO DEFICIENCY VIRUS -1

The development of a highly effective AIDS vaccine will depend on the success of designing immunogens that will elicit immune response against broadly neutralizing antibodies to naturally circulating strains of HIV- can be done by reverse vaccinology. Reverse vaccinology is a good approach for provoking the broadly neutralizing antibody response by identifying the specific epitopes i.e. surface pr...

Amol M. Kanampalliwar*, Amandeep Girdhar, Rakesh Arya, Rupali Saxena and Archana Tiwari

School of Biotechnology, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal , MP, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2662-86

2662-2686

1274

603

12.

A COMPARATIVE STUDY TO EVALUATE THE EFFECT OF HIGHLY STANDARDISED AQUEOUS EXTRACTS OF PHYLLANTHUS EMBLICA, WITHANIA SOMNIFERA AND THEIR COMBINATION ON ENDOTHELIAL DYSFUNCTION AND BIOMARKERS IN PATIENTS WITH TYPE II DIABETES MELLITUS

Introduction: Biomarkers of oxidative stress and endothelial dysfunction play an important role in the pathogenesis of type II Diabetes Mellitus (DM). The present study was planned to compare the effect of highly standardised aqueous extract of Phyllanthus emblica, Withania somnifera and theircombination on endothelial dysfunction and biomarkers of oxidative stress in patients with type II DM. ...

P. Usharani*, P.V. Kishan, Nishat Fatima and C. Uday Kumar

Department of Clinical Pharmacology & Therapeutics, Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2687-97

2687-2697

1753

1744

13.

IN VITRO COMPARATIVE STUDY OF MEMBRANE STABILIZATION CAPACITY OF DIFFERENT EXTRACTS OF BLEPHARIS MADERASPATENSIS (L.) HEYNE EX ROTH. AND BLEPHARIS MOLLUGINIFOLIA PERS. GROWN IN THE REGION OF MYSORE, KARNATAKA

Blepharis is a genus belonging to family Acanthaceae. It is an Afro-asiatic genus comprising 129 species which occur in arid and semi-arid habitats. They are used for the treatment of a number of ailments. Anti-inflammatory activity was performed based on the folk lore information. The present study is aimed at the evaluation ofanti-inflammatory property of the petroleum ether, ethyl acetate and e...

H.S. Neelambika* and S. Leelavathi

DOS in Botany, University of Mysore - 570 006, Karnataka, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2697-01

2698-2702

1321

623

14.

AMYLASE PRODUCTION ON SOLID STATE FERMENTATION BY WILD TYPE AND MUTANT BACILLUS LICHENIFORMIS & ASPERGILLUS NIGER FROM AGRO-WASTES

Cultures of Aspergillus niger and Bacillus licheniformis were procured from NCL, Pune. Obtained cultures were exposed to UV irradiation. Mutants of Aspergillus niger exposed to 30 and 50 min UV and Bacillus licheniformis exposed to 20 and 30 min UV were selected. Growth of wild type and mutated Aspergillus niger and Bacillus licheniformis was found to be optimum at 48 hrs of incubation time, 30°C...

R.N. Shinde*, M.J. Dhangar and R.B. Narwade

K. K. Wagh College of Agricultural Biotechnology Saraswati Nagar, Panchavati, Nashik – 422003, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2703-13

2703-2713

2883

1001

15.

DETERMINATION OF DRUGS BASED ON OXIDATION BYALKALINE KMNO4: A KINETIC SPECTROPHOTOMETRIC STUDY

Simple, accurate and precise spectrophotometric methods for quantitative determination of four drugs viz., Alfuzosin (ALF), Esomeprazole (ESO), Indomethacin (IND), Ketorolac Tromethamine (KET) have been developed based on oxidation of the drugs by alk.KMnO4. Kinetics of the oxidation reaction is followed spectrophotometrically, as one of the reaction product, Mn(VI), absorbed at 610 nm. Initial ra...

K. Damodhar Reddy, K. Sayanna and G. Venkateshwarlu*

Department of Chemistry, Osmania University, Hyderabad, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2714-21

2714-2721

1229

1121

16.

STUDYING THE EFFECT OF DISPERSED DRUG CRYSTAL IN THE ORGANIC PHASE ON THE ENCAPSULATION BY SOLVENT EVAPORATION TECHNIQUE; (2) X-RAY DIFFRACTION AND DSC AS TOOLS TO STUDY THE MICROCAPSULE STRUCTURE IN RELATION TO THE SUGGESTED DIVISION MECHANISM

The method of entrapment of the drug in the microcapsules structure prepared with different theoretical drug content (TDC) and having different particle size ranges were studied using x-ray diffraction and DSC analysis methods. Also, in the light of the analysis methods, a trial to correlate the actual microcapsule structure with the actual drug content (ADC) and the division mechanism suggested b...

Omar Mady

Department of Pharmaceutical Technology, Faculty of Pharmacy, Tanta University, Egypt

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2722-31

2722-2731

1357

527

17.

FATTY ACIDS OF HIPPOCRATEA AFRICANA ROOT: ANTIOXIDANT AND ANTI-MICROBIAL ACTIVITY

In this study, the fatty acid content, antioxidant activities and antimicrobial potential of oil obtained from the root of Hippocratea africana was investigated. Results showed that the oil was characterized by oleic acid (65.73%), palmitic acid (20.34%) and linoleic acid (6.90%) as the most abundant fatty acids with a oleic acid/linoleic acid ratio of 9.52. The oil possessed potent antioxidant ac...

B. N. Ita* and R. Ngochindo

Department of Chemistry, University of Uyo, Akwa Ibom State, Nigeria

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2732-37

2732-2737

1287

678

18.

ANTIDIABETIC ACTIVITY OF 1-(4-(DIMETHYLAMINO)BENZYLIDENE)-5-(2-OXO INDOLIN-3-YLIDENE) THIOCARBOHYDRAZONE IN RATS

Objective: The present study was aimed to evaluate the antidiabetic activity of 1-(4-(Dimethylamino) benzylidene)-5-(2-oxoindolin-3-ylidene) thiocarbohydrazone i.e. a novel Isatin derivative diabetic rats. Methods: The antidiabetic activity of Isatin derivative was evaluated against alloxaninduced diabetes in rats. Diabetes in rats was induced by administration of alloxan monohydrate (120...

Ch. Tejasree , G. Kiran , G. Rajyalakshmi and A. Rama Narsimha Reddy*

Department of Pharmacology, Vaageswari College of Pharmacy 1, Beside LMD Police Station, Karimnagar-505481, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2738-43

2738-2743

1209

551

19.

ELECTROCHEMICAL STUDY OF INTERACTION OF THE HEAVY METAL IONS IN HYDROXYLATION REACTION OF SALICYLIC ACID ON GLASSY CARBON ELECTRODE

The formation of free hydroxyl radical (˙OH) in oxygen transfers at GCE and the reaction between the electrochemically produced ˙OH and salicylic acid (SA) is studied by cyclic voltammetry method. Experiments showed that ˙OH is formed in the potential range of 1.0-1.4V corresponding to the anodic discharge of H2O at the GCE. The interaction of Cu2+, Hg2+, Cd2+, Mn2+ ions on the hydroxylation re...

B. Marichamy, A. Firose and N. Ramalakshmi*

Post-Graduate and Research Department of Chemistry, Presidency College, Chennai-05, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2744-53

2744-2753

1434

428

20.

CYCLODEXTRIN GLYCOSYLTRANSFERASE PRODUCTION BY ALKALIPHILIC BACILLUS SP. ISOLATED FROM RICE CULTIVATED SOIL AND MEDIA OPTIMIZATION USING TAGUCHI METHOD

A Cyclodextrin glycosyltransferase (CGTase) producer was isolated from soil obtained from rice fields using alkaline Horikoshi II medium. The alkaliphile was characterized microscopically, biochemically and confirmed by 16S rRNA analysis as Bacillus oshimensis. CGTase production is dependent on the strain, medium composition and culture conditions; hence media optimization studies were carried out...

R. Kamble and A. Gupte*

Department of Biotechnology and Bioinformatics, Padmashree Dr. D. Y. Patil University, Plot No. 50, Sector 15, CBD Belapur, Navi Mumbai 400614m Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2754-62

2754-2762

1380

649

21.

IDENTIFICATION OF E.COLI NISSLE 1917 PROTEINS BY USING 2-D GEL ELECTROPHORESIS UNDER THE INFLUENCE OF COCOS NUCIFERA SAP AND WINE

Proteomics is the large scale study of proteins. Before going to analyse the differentially expressed proteins, through 2-D gel electrophoresis the proteins were extracted in a sample under stress.  In the present study, we were isolated the protein samples of E. coli Nissle 1917 treated with cocoti sap and wine stress. The isolated proteins washed with 2-D clean up kit because it was very sensit...

K. Chandrasekhar, S. Sreevani and J. Pramoda Kumari*

Dept. of Microbiology, S.V.University, Tirupati, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2763-71

2763-2771

1347

581

22.

PHYSIOCHEMICAL EVALUATION, PHYTOCHEMICAL SCREENING AND CHROMATO-GRAPHIC FINGERPRINT PROFILE OF WOODFORDIA FRUTICOSA (L.) KURZ EXTRACTS

Woodfordia fruticosa (L.) Kurz. is a plant with vast medicinal properties. The plant and its parts are reported to be used for the treatment of hemorrhoids, dysentery, diarrhoea, liver diseases, piles, leucorrhoea, menorrhagia, ulcers, wounds, skin diseases, fever, headache, herpes, etc. The present work attempts to evaluate the physicochemical and preliminary phytochemical screening using var...

Neha Grover, Rishikesh Meena* and Vidya Patni

Plant Tissue Culture and Biotechnology laboratory, Department of Botany, University of Rajasthan, Jaipur, Rajasthan, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2772-82

2772-2782

2283

3213

23.

FORMULATION AND IN-VITRO EVALUATION OF BUPROPION HYDROCHLORIDE CONTROLLED RELEASE TABLET

The aim of the study was to develop and evaluate matrix based controlled drug delivery system of Bupropion hydrochloride. Controlled release tablets were prepared by employing Guar gum, Eudragit RS 100, HPMC K15M, HPMC K100M at different concentration. All 13 batches passed friability, hardness, weight variation, assay but only four batches (CRB7W, CRB8W, CRB10W, and CRB11W) passed the dissolution...

Anjan Paudel*, Subash Tha Shrestha, Yogendra Raj Pandey and Sumit Chandra Shrestha

Faculty of Pharmacy, Asian College for Advanced Studies, Purbanchal University, Lalitpur, Nepal

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2783-90

2783-2790

1283

1551

24.

MS/MS AND HPLC CHARACTERIZATION OF FORCED DEGRADATION PRODUCTS OF DUTASTERIDE AND TAMSULOSIN HYDROCHLORIDE

A new simple and sensitive reverse phase high performance liquid chromatographic method was developed for simultaneous estimation of Dutasteride and Tamsulosin hydrochloride following forced degradation studies as per ICH guidelines. The degradation products were observed in acid and alkaline hydrolysis for Dutasteride; whereas Tamsulosin hydrochloride showed degradation on exposure to light. All ...

Rohit Chaudhari, Krishnapriya Mohanraj and Vaishali Shirsat*

Bombay College of Pharmacy, Kalina, Santacruz (E), Mumbai-400098, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2791-06

2791-2806

2080

505

25.

ANTIDEPRESSANT EFFECTS OF FRUIT EXTRACT OF ELAEOCARPUS GANITRUS IN FORCE SWIM TEST

The present study was designed to evaluate antidepressant effects of fruit extract of Elaeocarpus ganitrus(75% ethanol)on albino mice. Albino mice of either sex, weighing 25-30g were divided into seven groups and each group contains six animals. The animals were housed in polypropylene cages (38×23×10cm3) with not more than six animals per cage. Group I, II and III were administered orally with ...

Amit Dadhich, Nakuleshwar Dut Jasuja*, Subhash Chandra and Gargi Sharma

Department of Biotechnology and Allied Science, Jayoti Vidyapeeth Women’s University, Jaipur, Rajasthan, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2807-12

2807-2812

1387

842

26.

A NOVEL, SENSITIVE, BIOANALYTICAL METHOD FOR ESTIMATION OF AMLODIPINE BESYLATE IN RAT PLASMA USING FLOURESCENCE DETECTION BY RP-HPLC

The aim of the present work was to develop and validate a novel, rapid, sensitive, accurate and specific RP-HPLC assay with fluorescence detection for the quantification of amlodipine besylate in rat plasma to be applied to preclinical studies. Flourescein was used as internal standard (IS) and the detection was carried out by an online wavelength switching which enabled detection of amlodipine &a...

A. Varghese*, N. Pandita and R.S. Gaud

Department of Pharmaceutical Analysis, Shobhaben Pratapbhai Patel, School of Pharmacy and Technology Management, SVKM’s NMIMS, Vile Parle (W), Mumbai-400056, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2813-20

2813-2820

1214

901

27.

A STUDY TO EVALUATE THE IN VITRO ANTIMICROBIAL ACTIVITY AND ANTIANDROGENIC EFFECTS ON RATS OF Cr (III) COMPLEXES OF S∩N DONOR LIGANDS

The present paper deals with synthesis and characterization of some new chromium (III) Schiff base complexes using microwave irradiation technique as well as conventional heating. The S∩N donor benzothiazolines, 1-(2-furanyl) ethanone benzothiazoline (Bzt1N∩SH), 1-(2-thienyl) ethanone benzothiazoline (Bzt2N∩SH) and 1-(2-pyridyl) ethanone benzothiazoline (Bzt3N∩SH) were prepared by the cond...

Nighat Fahmi*, Ramhari Meena, Pradeep Mitharwal, Sumit Shrivastava and R.V. Singh

Department of Chemistry, University of Rajasthan, Jaipur 302 004, Rajasthan, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2821-33

2821-2833

2228

572

28.

HPTLC DENSITOMETRIC QUANTIFICATION OF SECONDARY METABOLITES FROM POLYCARPAEA CORYMBOSA LAMS

Polycarpaea corymbosa has been used traditionally as medicine for the treatment of various ailments. In the present investigation an attempt has been made to quantify phenol, flavonoid and steroid in methanol extract of aerial and root parts of P.corymbosa Lam. by HPTLC method. Different compositions of the mobile phase for HPTLC analysis were tested in order to obtain high resolution and re...

Sindhu Subramanian* and S. Manorama

PG and Research Dept. of Botany Kongunadu Arts and Science College (Autonomous), Coimbatore-29, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2834-40

2834-2840

1187

825

29.

MICROENCAPSULATION OF ISONIAZID BY TEMPERATURE CHANGE METHOD: PREPARATION AND CHARACTERIZATION

Aim: Isniazid is unstable in aqueous medium. The aim is to improve the aqueous stability of isoniazid by microencapsulation method. Methods: Isoniazid microcapsules were prepared by temperature change method. Ethyl cellulose used as coating material which forms a layer on pure drug. Ethyl cellulose was insoluble in cold cyclohexane when temperature rise about 70-750C it become soluble in cyc...

Athar Husain*, Amit Kaushik and Mohd. Rashid Ansari

Mahatma Gandhi Institute of Pharmacy, Junabganj, Kanpur Road, Banthra, Lucknow, U.P. India-227101

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2841-47

2841-2847

2794

743

30.

STABILITY INDICATING FORCED DEGRADATION RP-HPLC METHOD DEVELOPMENT AND VALIDATION OF OLMESARTAN MEDOXOMIL

A simple, precise, accurate, economical and reproducible HPLC method for estimation of Olmesartan in tablet dosage form has been developed. Quantitative HPLC was performed with HITACHI L2130 with D Elite 2000 Software with Isocratic with UV-Visible Detector (L-2400), PUMP (LC-IOAT). C18 Develosil ODS HG-5 RP 150mm x 4.6mm 5µm particle sizecolumn receptor in vascular muscle. Its action is therefor...

A. Srinivas* and Y. Sneha

SRR College of Pharmaceutical Scienes, Valbhapur (V), Elkathurthy (M), Karimnagar (Dist) - 505 476, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2848-55

2848-2855

1707

428

31.

TOXICITY STUDIES OF AQUEOUS EXTRACT OF BRIDELIA MICRANTHA STEM ADMINISTERED ON MICE AND RATS

The World Health Organization (WHO) defines traditional medicine as “the health practices, approaches, knowledge and beliefs incorporating plants, animals and mineral-based medicines, spiritual therapies, manual techniques and exercises, applied singularly or in combination to treat, diagnose and prevent illness or maintain wellbeing. Various compounds have been isolated from Bridelia micrantha ...

E.O. Oshomoh*, M. Idu and D. Uwaya

Department of Plant Biology and Biotechnology, Faculty of Life Sciences, University of Benin, Benin city, Edo State. Nigeria

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2856-65

2856-2865

1286

684

32.

FACILE AND ECO-FRIENDLY METHOD FOR THE SYNTHESIS OF ZINC OXIDE NANOPARTICLES USING AZADIRACHTA AND EMBLICA

The evolution of green chemistry in the production of nanoparticles has wrapped up an immense consideration because traces of chemicals left unreacted in the chemical synthesis process can be precarious. Owing to copious interest a competent protocol for the production of ZnO NPs without calcinations was developed by green synthesis method using aqueous leaf extracts of Azadirachta Indica and Embl...

D. Gnanasangeetha* and Sarala D. Thambavani

Department of Chemistry, PSNA College of Engineering and Technology, Dindigul, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2866-73

2866-2873

1894

2122

33.

PHYTOCONSTITUENTS INVESTIGATION BY LC-MS AND EVALUATION OF ANTI-MICROBIAL AND ANTI-PYRETIC PROPERTIES OF CYNODON DACTYLON

Among numerous species of plants growing in the wild in India, Garike, orDruva or taxonomically the Cynodon dactylon sp. occupies its unique place in the traditions, religions and cultures of different societies. In the present study, Phytochemical screening of methanolic, petroleum ether, ethanolic and aqueous extracts of Cynodon dactylon revealed the presence of 17 different phytoconstituents. Q...

Zabin K. Bagewadi*, Siddanagouda R.S and Praveen G. Baligar

Department of Biotechnology, B.V. Bhoomaraddi College of Engineering & Technology, Hubli-580031, Karnataka, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2874-89

2874-2889

1739

2005

34.

ROLE OF LIQUID MEMBRANE HYPOTHESIS IN THE MECHANISM OF ACTION OF ERTAPENEM

The role of liquid membrane hypothesis has been studied in the mechanism of action of Ertapenem. In the present study transport of selected permeants (glucose, p-amino benzoic acid and ions like magnesium, ammonium, phosphate, calcium, sodium, potassium and chloride) through liquid membrane generated by Ertapenem in series with supporting membrane has been studied. The results indicate that the li...

Abhay K. Jain *, Manish Srivastava and Sharad K. Gupta

Department of Chemistry, D. D. U. Gorakhpur University, Gorakhpur - 273009, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2890-95

2890-2895

1212

445

35.

ANTIOXIDANT ACTIVITY OF TAXIFOLIN OBTAINED FROM METHANOLIC EXTRACTS OF CORDIA DICHOTOMA LINN. SEEDS

Cordia dichotoma L. family Boraginaceae is a medium sized tree, is taken as food. The immature fruits are pickled and are also used as vegetable. The various extracts and fractions of Cordia dichotoma were screened for their free radical scavenging properties using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and comparing it with butylated hydroxyl toluene (BHT) as standard antioxidant...

Mahasweta Roy*, Bhupendra Kumar, Nishant Kumar, Amrit Patel and Babita Kumar

College of Pharmacy, Shree Ganpati Institute of Technology, Ghaziabad, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2896-01

2896-2901

1448

512

36.

DEVELOPMENT AND VALIDATION OF A HPLC-UV METHOD FOR SIMULTANEOUS DETERMINATION OF MOXIFLOXACIN HYDROCHLORIDE AND KETOROLAC TROMETHAMINE IN OCULAR FORMULATION

A simple, rapid, and sensitive high-performance liquid chromatographic method with UV detection has been developed and validated according to the ICH guidelines for the quantitation of Moxifloxacin Hydrochloride (MOX), Ketorolac Tromethamine (KET) in pharmaceutical dosage form. Chromatographic separation was carried out in a Zorbax eclipse plus, C18 column (250 mm × 4.6 mm; 5 µm particle size) w...

Tapas Majumder, Sarbojit Kundu*, Subrata Kumar Ray and Prasanta Kumar Barat

Central Drugs Laboratory, (Govt. of India), 3, Kyd Street, Kolkata-700 016, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2902-07

2902-2907

1697

1176

37.

MULTI-DRUG RESISTANT PATTERNS OF BIOFILM FORMING AEROMONAS HYDROPHILA FROM URINE SAMPLES

Biofilm are a matrix of microorganisms which are adhered to and colonized a surface. When formed they are very difficult to remove and act as a source of contamination in processing environments. As bacteria in biofilm exhibit enhanced resistance to antibiotics and clearance by the host immune system, the resistance of enteropathogenic bacteria to commonly prescribed antibiotics is increasing both...

S. Thenmozhi*, P. Rajeswari, B.T. Suresh Kumar, V. Saipriyanga and M. Kalpana

Department of Microbiology, Vivekanandha College of Arts and Sciences for Women (Autonomous) Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2908-18

2908-2918

1341

672

38.

ASSESSMENT OF FOOD, ETHNOBOTANICAL AND ANTIBACTERIAL ACTIVITY OF TRICHOSANTHES CUCUMIRINA L.

Trichosanthes cucumirina L., locally known as “Chachindra” among the tribal and rural mass of Similipal Biosphere Reserve (SBR) forest. Plant parts are used as ethnomedicine among inhabitants of SBR. They use the fruits, leaves and roots against various diseases and traditional practices are continuing since long. Leaves are used against microbial infections, roots against diabetic and fruits ...

Prakash Kumar Tripathy, Sanjeet Kumar and Padan Kumar Jena*

Department of Botany, Ravenshaw University, Cuttack, Odisha, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2919-26

2919-2926

1180

470

39.

A CASE STUDY ON RUBIA CORDIFOLIA L IN FILM COATING OF TRIPHALA GUGGLE AYURVEDIC TABLETS

Alizarin [1, 2 di hydroxy anthraquinone] is the major pigment, extracted from Rubia Cordifolia L. The aim of the present work is to extract manjith dye and alizarin pigment from Rubia Cordifolia L., and use it in the film coating of triphala guggle ayurvedic (TGA) tablet. The optimum extraction conditions for manjistha dye are 600C and 60 minute stirring with methanol (80%) and M:L ratio(1:10) wit...

N. Rani*, A. Goel and M.K. Bhardwaj

Department of Chemistry, KGC, Gurukul Kangri Vishvavidhyalaya, Haridwar- 249407, Uttarakhand, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2927-35

2927-2935

1709

1228

40.

OPTIMIZED FORMULATION OF VANCOMYCIN LOADED THERMOREVERSIBLE HYDROGEL FOR TREATMENT OF ORTHOPEDIC INFECTIONS

The aim of the present study was to develop suitable controlled release injectable vancomycin thermoreversible chitosan/ β-glycerophosphate hydrogel system for treatment of orthopedic infections. The effect of different formulation variables on the gelation temperature was studied. The prepared vancomycin loaded Chitosan/β-glycerophosphate thermoreversible hydrogels were characterized regarding ...

Hend Mohamed Abdel-Bar, Amal Youssef Abdel-Reheem, Rihab Osman*, Gehanne A.S. Awad and Nahed Mortada

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2936-46

2936-2946

1536

887

41.

VIRTUAL SCREENING OF NOVEL HIV-RT NNRT INHIBITORS USING ZINC DATABASE

Non-nucleoside reverse transcriptase inhibitors (NNRTI) are a group of small hydrophobic compounds with diverse structure that specifically inhibit HIV-1 reverse transcriptase (RT) by allosteric bind to change its conformation. NNRTIs interact with HIV-1 RT by binding to a single site on the p66 subunit of the p66/p51 heterodimeric enzyme, termed the NNRTI-binding pocket (NNRTI-BP), binding intera...

Rituraj*and Md. Tanweer Alam

Department of Chemistry, Vinoba Bhave University, Hazaribagh, Jharkhand, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2947-54

2947-2954

1122

830

42.

SERUM CREATININE LEVEL IN HYPERTENSIVE PATIENTS: A STUDY FROM UTTARAKHAND, INDIA

Chronic Kidney diseases are increasingly recognized as a problem worldwide. Incidence of chronic kidney diseases is doubled in last fifteen years. The kidney is both cause and victim of hypertension. Hypertension is a serious risk factor for chronic kidney disease. The purpose of this study was to measure serum creatinine level in hypertensive patients as an indicator of kidney functioning and com...

Pooja* and Yashoda Mittal

Department of Zoology, Government Post Graduate College, Rishikesh, District – Dehradun, Uttarakhand, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2955-59

2955-2959

1691

1300

43.

HISTOPATHOLOGICAL AND ULTRASTRUCTURAL STUDIES OF THE EFFECT OF FENUGREEK SEED EXTRACT ON PANCREAS OF ALLOXAN INDUCED DIABETIC MICE

To evaluate the protective effect of fenugreek (Trigonella foenum graecum L.) on alloxan induced diabetic mice, 15 male albino mice weighing 26-30 gm were used. They were divided into 3 groups. Control group received subcutaneous injection of 0.15 M acetate buffer for 15 days. Alloxan induced group received subcutaneous injection of alloxan 150 mg/ kg body weight to induce diabetes. Recovery group...

M.V. Walvekar*, S.B. Pol and .K. Chandrasekhar Sagar

Department of Zoology, Shivaji University , Kolhapur, Maharashtra, India

DOI: madhuri_walvekar@rediffmail.com

2960-2965

1263

707

44.

SYNTHESIS, CHARACTERIZATION OF SOME 2-AZETIDINONE DERIVATIVES FROM 4- NITRO ETHYL BENZOATE BY MICROWAVE METHOD AND EVALUATION OF THEIR ANTIMICROBIAL ACTIVITY

Non classical, High-speed, environmentally benign synthesis with microwaves has attracted researchers for organic synthesis a considerable amount of attention in recent years. An expeditious one pot microwave irradiation method for preparation of 2-azetidinones is developed. This method has been assessed as greener methodology. In our present study, series of five novel azetidinones  are synthesi...

S.K. Gawande* and R.E. Khadsan

Department of Applied Science and Humanities, Mauli College of Engineering and Technology, Shegaon – 444 203 Dist – Buldana, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2966-71

2966-2971

1541

1722

45.

SESAME OIL INCORPORATED MEDIUM FOR ISOLATION AND ENUMERATION OF LIPOPHILIC YEASTS

This communication reports on an easy and cost effective mycological medium, developed for primary isolation and culture of lipophilic yeasts. The medium has been modified and adjusted specifically to promote the growth of lipophilic yeasts and simultaneously suppress the growth of other fungi and bacteria. The traditional medium of Sabouraud’s dextrose agar (SDA) with olive oil overlay was modi...

V. Agrawal*, A.M. Bhagwat and C.S. Sawant

School of Science NMIMS 1 (Deemed to be University), Mumbai, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2972-79

2972-2979

1374

3009

46.

NUTRITIONAL ASSESSMENT OF DIFFERENT PARTS OF ACACIA CATECHU WILLD. COLLECTED FROM CENTRAL INDIA

Acacia catechu is a multipurpose tree predominantly found in tropical and subtropical regions of India. The tree produces nitrogen rich fodder and green manure, high quality fuel wood and charcoal, strong durable poles and timber. The most useful products of this tree are Kutch or “Kattha” which is obtained from bark and heartwood of the tree. Commonly used plant part of Acacia catechu is bark...

K.S. Verma*, R. Pandey and A. Ayachi

Department of Biological Sciences 1, R.D. University, Jabalpur, Madhya Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2980-86

2980-2986

1911

2603

47.

IN VITRO ANTI-INFLAMMATORY ACTIVITY OF VARIOUS EXTRACTS OF LEAF AND BARK OF HOLOPTELIA INTEGRIFOLIA PLANCH

The different extracts of leaf and bark of the plant Holoptelia integrifolia were investigated for in-vitro anti-inflammatory activity by human red blood cell membrane stabilization (HRBC) method.  The HRBC membrane stabilization activity of the petroleum ether extract of   leaf  at the concentration of 200 mg/ml showed 68.12+/-1.05 % and petroleum ether extract of bark at the concentration of...

Padmaja , Chinna Eswaraiah and Amgoth Srinivas Nayak*

University College of Pharmaceutical Sciences, Satavahana University, Karimnagar-505001, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2987-90

2987-2990

1229

461

48.

ANTIFERTILITY INVESTIGATIONS ON THE ETHANOL EXTRACT OF EUGENIA SINGAMPATTIANA BEDD LEAF IN MALE ALBINO RATS

Antifertility effect of ethanol extract of leaf of Eugenia singampattiana was observed in male albino rats. The relative weight of the testes and epididymis were decreased. The epididymal sperm count, motility and sperm abnormality were reduced significantly in treated rats. There was an increase in serum urea, creatinine and the activity of liver marker enzyme (SGOT) levels of drug treated rats. ...

S. Mary Jelastin Kala, P.S. Tresina and V.R. Mohan*

Ethnopharmacology Unit, Research Department of Botany , V.O. Chidambaram College, Tuticorin-628008, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2991-98

2991-2998

1451

776

49.

GAS CHROMATOGRAPHY-MASS SPECTROMETRY ANALYSIS OF KYLLINGA TRICEPS

Objective: To isolate and analyze the chemical components in crude methanolic extract from the South Indian medicinal plant of Kyllinga triceps by gas chromatography-mass spectrometry (GC-MS). Methods: Preliminary phytochemical screening of the extract was carried out according to the standard method described by Brindha et al. The shade dried powder was extracted with methanol by using s...

Siddabathuni Aneela ⃰ , Akalanka Dey and Somnath De

Dr. Samuel George Institute of Pharmaceutical Sciences, Markapur- 523316, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2999-03

2999-3003

1423

814

50.

FORMULATION AND CHARACTERIZATION OF SOLID DISPERSIONS OF A POORLY SOLUBLE FENOFIBRATE

Solid dispersion is one of these methods, which was most widely and successfully applied to improve the solubility, dissolution rates and consequently the bioavailability of poorly soluble drugs. The solid dispersions based on the concept that the drug is dispersed in an inert water-soluble carrier at solid state. Several water soluble carriers such as methyl cellulose, urea, lactose, citric...

A. Prashanth Kumar

Prasad institute of Pharmaceutical Sciences, Jalgaon, Telangana, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).3004-17

3004-3017

1538

2423

51.

DESIGNING AND PHARMACEUTICAL EVALUATION OF FAST DISSOLVING TABLET OF FEXOFENADINE USING COPROCESSED SUPERDISINTEGRANTS

Among various novel drug delivery systems fast dissolving tablets have attracted great attention in recent years due to their ability to release the drug content gradually. Therefore the demand for this dosage form has been increased since last few years especially in patients with swallowing difficulties as this dosage form provides advantage of being swallowed without water. The objective of thi...

Shiv Shankar Hardenia*, G.N. Darwhekar , Shailesh Sharma and Anu Hardenia

College of Pharmacy IPS Academy , Department of Pharmaceutics, Indore, Madhya Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).3018-30

3018-3030

1619

569

52.

QUALITY EVALUATION OF THE COMMONLY PRESCRIBED ANTIPSYCHOTIC DRUGS (CHLORPROMAZINE & THIORIDAZINE TABLETS) MARKETED IN ETHIOPIA

The purpose of this study was to evaluate the quality of the commonly prescribed imported and locally manufactured antipsychotic drugs (chlorpromazine and thioridazine tablets) that are marketed in drug retail outlets in Ethiopia. Four different sources of Chlorpromazine and two thioridazine tablets were assessed in this investigation. The quality of the samples was examined in seven aspects: perc...

Gebremariam Birhanu, Ariaya Hymete, Asfaw Debella and Ayenew Ashenef*

Department of Pharmaceutical Chemistry and Pharmacognosy , School of Pharmacy, College of Health sciences, Addis Ababa University, Addis Ababa, Ethiopia.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).3031-41

3031-3041

1628

1650

53.

ASSESSMENT OF OXIDATIVE STRESS, ANTIOXIDANT ENZYMES AND LIPID PROFILE IN THE SUBJECTS OF CORONARY ARTERY DISEASE (CAD)

Coronary artery disease (CAD) is the major cause of mortality and morbidity worldwide. The incident of CAD is rising and they are predicted to be the biggest causes of death by 2020 in India. Therefore, the aim of the present study was to assess the association of oxidative stress, antioxidant enzyme and lipid status parameters in CAD patients and to compare the results age- sex matched healthy co...

Sumit Kumar Thakur *, Kalpana Jaggi , Brijesh Rathore , Ramesh Chander, Farzana Mahdi and Abhishek Mathur

Department of Biochemistry, Era’s Lucknow Medical College & Hospital, Sarfarazganj, Hardoi Road, Lucknow, (U.P) India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).3042-46

3042-3046

1605

611

54.

OXIDATIVE STRESS INDUCED ALTERATION OF PROTEIN AND NUCLEIC ACID METABOLISM IN FLUORIDE-INTOXICATED RAT BRAIN: PROTECTION BY 3α-HYDROXY OLEAN-12-EN-27-OIC ACID ISOLATED FROM NEANOTIS WIGHTIANA

Increased production of reactive oxygen species plays important role in pathogenesis of chronic fluoride toxicity resulting from prolonged exposure to fluoride. Oral (NaF) fluoride administration to rats at 20 mg/kg b.w./day for 30 days resulted in elevation in MDA, free amino acid N2, NO level and decreased activities of SOD, GPx, CAT, GR and reduced non enzymatic antioxidant like GSH. Significan...

Chaitali Sarkar, Niranjan Das , Sudipta Pal * and Biswanath Dinda

Nutritional Biochemistry Laboratory, Department of Human Physiology1, Tripura University, Suryamaninagar-799 022, West Tripura, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).3047-66

3047-3066

2757

614

55.

ANTIMICROBIAL POTENTIAL OF SOME INDIAN MEDICINAL PLANTS AGAINST DRUG-RESISTANT PATHOGENS

Many infectious diseases are known to be treated with herbal remedies throughout the history of mankind. Even today, plant materials continue to play a major role in primary health care as therapeutic remedies in many developing countries. Traditional system of medicine is found to have utilities as many accounts. Due to population rise adequate supply of drug and high cost of treatment in side ef...

Asima Shaban *, Satish K. Verma and Abhishek Mathur

Dept. of Research & Development, Institute of Transgene Life Sciences , Dehradun (U.K), India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).3067-71

3067-3071

1222

592

56.

PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL ACTIVITIES OF SOME WILD MEDICINAL PLANTS OF THE WESTERN MEDITERRANEAN COASTAL REGION, EGYPT

Four wild plant species (Chrysthanthemum cornarium, Capparis spinosa, Carthamus lanatus, Haplophyllum tuberculatum) were investigated for their antioxidant activity, phenolic and flavonoid contents of their methanolic extracts. The antioxidant activity of the extracts was assessed their free radical scavenging properties using DPPH. Total phenolics and total flavonoids were detected by spectrophot...

H.M. Abou-Zeid*, L.M. Bidak and Y.M. Gohar

Botany & Microbiology department, Faculty of Science, Alexandria University, Egypt

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).3072-80

3072-3080

1180

582

57.

A COMPARATIVE STUDY OF THE IN VITRO ANTIBACTERIAL ACTIVITY OF ENDOCARP, DATE PALM TISSUE AND DATE PALM TISSUE WITH ENDOCARP TOGETHER AGAINST SOME GRAM NEGATIVE AND GRAM POSITIVE PATHOGENIC BACTERIA

The antibacterial activities of water extracts of the three major parts of the date palm fruit were compared against Eschereshia coli; Klebsiella pneumonia; Salmonella enteritidis; Pseudomonas aeruginosa; Staphylococcus aureus using the agar well diffusion method. Endocarp extract showed a wide range of activity against all Gram negative bacteria while it exhibited a low activity against Gram posi...

R Al Qroom and W.M Al Momani*

Department of Allied Medical Sciences, Al Balqa’ Applied University, P.O. Box 19117, Al-Salt, Jordan

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).3081-84

3081-3084

1130

522