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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

Inclusion in Web of Science (Thomson Reuters) - ESCI
Projected Impact Factor (2018): 0.83 , CiteScore (2017): 0.27
Five-Year Projected Impact Factor: 1.81

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Volume 9 (2018) - Issue 7, July

Review Articles

 
Title
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1.

SCORPION VENOM AND ITS COMPONENTS AS NEW PHARMACEUTICAL APPROACH TO CANCER TREATMENT, A SYSTEMATIC REVIEW

The use of scorpion venom has a very old history in traditional medicine for thousands years ago in China, India and Africa worldwide. The inhibition of cancer progression and induce apoptosis have shown in an increasing number in-vitro and in-vivo studies. We accomplished this systematic review to evaluate the performance of scorpion venom and its components in the growth inhibition of cancer cel...

M. Moradi, R. Solgi, B. Vazirianzadeh, H. Tanzadehpanah and M. Saidijam *

Molecular Medicine Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

DOI: 10.13040/IJPSR.0975-8232.9(7).2604-15

2604-2615

2528

1179

2.

MIDDLE EAST RESPIRATORY SYNDROME (MERS): A SYSTEMATIC REVIEW

The first case of middle east respiratory syndrome (MERS) was identified in a mid-aged Saudi Arabian resident in 2012. The syndrome is analogous to severe acute respiratory syndrome (SARS) in its clinical course, with a male predominance in incidence. MERS virus is disseminated as a result of close proximity of people to camels, person to person transmission being uncommon and confined to hospital...

P. A. Khan, B. B. S. Nousheen *, N. Maryam and K. Sultana

Department of Pharmacy Practice, Anwarul Uloom College of Pharmacy, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2616-25

2616-2625

1635

592

3.

CHITIN, CHITOSAN AND THEIR PHARMACOLOGICAL ACTIVITIES: A REVIEW

Chitin is the second most important natural amino polysaccharide polymer after cellulose in the world.  The main sources exploited are marine crustaceans, shrimp, and crab apart from that some other lobstera, insects, sulphur butter and fungi. Chitosan is the most important natural based common cationic polymer got from chitin has gotten developing consideration for the most part due to their bio...

K. Tripathi and A. Singh *

Department of Pharmaceutical Sciences, Kumaun University, Nainital, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2626-35

2626-2635

2260

839

4.

THE ROLE OF EXTRACTS AND COMPOUNDS OBTAINED FROM HERBS IN TREATMENT OF PARKINSON’S DISEASE

Neurodegenerative disorders particularly Parkinson’s disease are serious threat for heath society. In addition, treatment, control and managing of Parkinson’s disease burden high cost to these patients. Therefore, an efficacy and available treatment strategy is required so that herbs and their bioactive compounds could be good candidates. It has well been demonstrated the herbs are a potential...

S. H. Hassanpour *, M. A. Dehghani, S. Z. Karami and F. Dehghani

Young Researchers and Elite Club, Yasooj Branch, Islamic Azad University, Yasooj, Iran.

DOI: 10.13040/IJPSR.0975-8232.9(7).2636-44

2636-2644

1554

656

5.

AN UPDATED REVIEW OF PHARMACOLOGICAL STUDIES ON AZADIRACHTA INDICA (NEEM)

Neem has become valuable plant in the world which shows the solutions for hundreds to thousands problems. Neem has become important in the global context today because it offers answers to the major concerns facing mankind. Neem has been extensively used in Ayurveda, Unani and Homoeopathic medicine and has become a centre of attraction of modern medicine. Azadirachta indica (neem) is a rapidly gro...

R. K. Bijauliya *, S. Alok, D. K. Chanchal, M. Sabharwal and M. Singh

Department of Pharmacognosy, Institute of Pharmacy, Bundelkhand University, Jhansi, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2645-55

2645-2655

3282

981

6.

ENHANCED HUMAN EXPOSURE TO RADIATIONS, ROLE OF PHYTOCHEMICALS AS POTENTIAL RADIO-PROTECTANTS: A REVIEW

Science and technology have greatly contributed to man’s never-ending quest for quality improvement in different domains of life. But in the process of development, the usage of radiation-based technologies has considerably increased in the fields of medicine, agriculture, aviation, space, warfare, food processing, electronic and communication systems, nuclear-power generation and other industri...

G. E. N. Hanumakumar, M. Balaji * and R. S. Karunakaran

Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2656-68

2656-2668

1109

397

7.

A DIETRY GUIDE TO PREVENTION AND MANAGEMENT OF OSTEOPOROSIS

Osteoporosis is a debilitating disease that affects many older people. Characterized by low bone mass and microarchitectural deterioration (MAD) of bone tissue, Fragility fractures are the hallmark of osteoporosis. There are potentially numerous nutrients and a dietry component that can influence bone health. Bone mineral consists of calcium phosphate, and phosphorus is as important as calcium i...

A. K. Quadri * and S. M. Shahidullah

Department of Pharmacy Practice, Deccan School of Pharmacy, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2669-74

2669-2674

956

353

8.

GROUNDWATER ARSENIC (As) CONTAMINATION AND SIMPLE LOW COST ARSENIC REMOVAL PROCESSES IN TRIPURA

Arsenic (As) is a metalloid. It occurs in almost every fraction of the environment. It is moving in each and every corner of our environment. Levels of arsenic (As) in the environment have become a global concern due to its toxicity and adverse effects on human health and other living beings. It is highly toxic even at low concentrations. It is also carcinogenic. Although, its natural sources are...

T. Bhattacharjee * and M. Goswami

Reproductive Physiology and Endocrinology Laboratory, Department of Human Physiology, Tripura University (A Central University) Suryamaninagar, Agartala, Tripura, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2675-80

2675-2680

1143

381

9.

TRANSETHOSOMES: A NEW PROSPECT FOR ENHANCED TRANSDERMAL DELIVERY

The skin covers a total surface area of approximately 1.8 m2 and provides the contact between the human body and its external environment. Transdermal route of drug delivery has gained great interest in pharmaceutical research as it overcomes many problems associated with the oral route of administration. Although the skin, particularly the stratum corneum presents a barrier to most drug absorptio...

J. Shaji * and R. Bajaj

Department of Pharmaceutics, Principal K. M. Kundnani College of Pharmacy, Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2681-85

2681-2685

1893

552

10.

CARBON NANOTUBE USAGE IN MEDICAL APPLICATIONS – REVIEW

Bulk nanocomposites prepared from aqueous albumin dispersion with carbon nanotubes by removing the liquid component from the dispersion have been investigated. The composites were obtained by thermostating and exposure to LED and IR diode laser radiation. The nanocomposites obtained under laser irradiation retain their shape and properties for several years, in contrast to the composites fabricate...

E. N. Ganesh

Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2686-92

2686-2692

1121

452

11.

KRILL OIL: THE MOST POWERFUL OMEGA 3 KNOWN ON EARTH

A diet rich in marine fishes and general seafood has long been recommended by several medical authorities as a long-term nutritional intervention to preserve overall health and wellbeing. An association between consumption of fish and seafood and beneficial effects on a variety of health outcomes has been reported in epidemiologic studies and clinical trials. These effects are mainly attributed to...

A. Sati * and P. Bhatt

Division of Pharmaceutical Sciences, Shri Guru Ram Rai Institute of Technology and Science, Patel Nagar, Dehradun, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2693-99

2693-2699

1583

383

12.

ANALYSIS OF DATA MINING AND SOFT COMPUTING TECHNIQUES IN PROSPECTING DIABETES DISORDER IN HUMAN BEINGS: A REVIEW

Diabetes is one of the deadliest and non-contagious diseases that can adversely affect several parts of human body. Early prognosis of diabetes can inkling the grievous complications and help to save human life. Several researchers have used different data mining (Iterative Dichotomiser 3, Random Forest, Support Vector Machine, k-Nearest Neighbour, C4.5) and soft computing (Genetic Algorithm, Ant ...

P. Kaur and M. Sharma *

Department of Computer Science and Applications, DAV University, Jalandhar, Punjab, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2700-19

2700-2719

1733

534

Research Articles

 
Title
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Cited
13.

ISOLATION AND CHARACTERIZATION OF A NOVEL ANTICANCER MUSCLE PROTEIN FROM EDIBLE MARINE CATFISH TACHYSURUS DUSSUMEIRI

Cancer, the uncontrolled growth of cells, has been estimated as a major cause of death among human population. Although there are many potential drugs, a much effective bioactive drug with less side effects are still in its pioneer stage of research. The aim of the study was to isolate, purify and characterize the anticancer muscle protein from edible marine catfish, Tachysaurus dussumieri, so as ...

K. M. Varier, A. Chinnasamy *, B. Gajendran and R. Nagarathnam

Department of Zoology, University of Madras, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2720-30

2720-2730

1318

564

14.

ROSMARINIC ACID ENHANCES CISPLATIN CYTOTOXICITY IN HEPG2 CELL LINE AND ATTENUATES ITS NEPHROTOXICITY IN MICE

The present study aimed to investigate the anticancer effect of rosmarinic acid (RA), both alone and in combination with cisplatin (cis). Also, the potential nephroprotective effects of RA against cis-induced nephrotoxicity in mice and the possible mechanisms underlying this protection were explored. Treatment of HepG2 cells with RA produced a significant decline in cellular proliferation. RA indu...

H. M. Hashiesh *, A. A. Elkhoely, A. A. Eissa and M. M. Youns

Department of Pharmacology and Toxicology, Faculty of Pharmacy, Helwan University, Cairo, Egypt.

DOI: 10.13040/IJPSR.0975-8232.9(7).2731-43

2731-2743

1143

476

15.

TUMOR NECROSIS FACTOR RECEPTOR 1 (TNFR1) NEUTRALIZATION AMELIORATED CARRAGEENAN-INDUCED INFLAMMATION IN MICE SUPPLEMENTED WITH HERBAL ANTIOXIDANTS

TNF-α plays pivotal role in initiation of inflammation via its interaction with TNFR1 in an O2.- induced oxidative stress dependent manner. The present study investigated whether the anti-oxidant effect of hydroalcoholic extract of Clitoria ternatea (CTE), could facilitate the anti-inflammatory effect of TNFR1 neutralization in context to carrageenan-induced acute inflammation in mice. Sub-planta...

R. Adhikary, A. Nandi, S. Sultana and B. Bishayi *

Department of Physiology, Immunology Laboratory, University of Calcutta, University Colleges of Science and Technology, Calcutta, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2744-59

2744-2759

1353

530

16.

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF MORPHOLINE MANNICH BASE DERIVATIVES

In the present study 10 morpholine mannich base derivatives were synthesized by three component reaction of morpholine, N-phenylacetamide and various substituted benzaldehydes. Progress of the reaction was monitored by thin layer chromatography and the compounds synthesized were characterized by ATR and 1HNMR techniques. Antimicrobial activity of the synthesized compounds was evaluated against gra...

H. Amin *, S. Wakode and R. K. Tonk

Centre for Medicinal Chemistry, Delhi Pharmaceutical Sciences and Research University, Pushp Vihar, New Delhi, Delhi, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2760-66

2760-2766

1346

572

17.

TRACE LEVEL QUANTIFICATION OF CYPIONYL CHLORIDE IN TESTOSTERONE CYPIONATE BY PRE COLUMN DERIVATIZATION WITH 2-BUTANOL BY GAS CHROMATOGRAPHY WITH ELECTRON IMPACT IONIZATION DETECTOR

The author has been proposed the precolumn derivatization method for the trace level quantification of cypionyl chloride in testosterone cypionate, it maybe potential impurity in the testosterone cypionate, it has to quantify in the testosterone drug Substance. The method development of cypionyl chloride has been started with gas chromatography with FID detector. The detection of cypionyl chloride...

N. Rajana *, P. Madhavan, J. M. Babu, K. Basavaiah and D. R. Devi

Scientist in Analytical Research and Development, Custom Pharmaceutical Services, Dr. Reddy’s Laboratories Ltd., Miyapur, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2767-72

2767-2772

1062

428

18.

DIETHYLSTILBESTROL (DES) INDUCED ENDOMETRIOSIS IN BALB/C MICE TREATED WITH MMP-2 AND 9 INHIBITORS-I

Diethylstilbestrol (DES) is an endocrine disturbing compound it can mimic and perform like a natural hormone, which mimics estradiol by binding to the estrogen receptor. This compound mainly reproductive target, so in this study used to induce endometriosis. Endometriosis is an estrone dependent constant gynaecological disorder. Here it, intends to induce endometriosis and treated by the MMP inhib...

M. Rajeswari and B. Kadalmani *

Department of Animal Science, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2773-82

2773-2782

980

324

19.

ISOLATION AND IDENTIFICATION OF ENDOPHYTIC FUNGI WITH ANTIMICROBIAL ACTIVITIES FROM THE LEAVES OF ELAEOCARPUS SPHAERICUS (GAERTN.) K. SCHUM. AND MYRISTICA FRAGRANS HOUTT.

Endophyte fungi reside in the tissues beneath the epidermal cell layers and live within a plant for at least part of its life without causing apparent diseases. Eight morphologically distinct endophytic fungi were selected from the medicinal plants Elaeocarpus sphaericus coded as ELSPF 1 to 4 and Myristica fragrans coded as MYFRF 1 to 4. The highest colonization frequencies (CF %) were found to be...

V. C. Deepthi, S. Sumathi, M. Faisal and K. K. Elyas *

Department of Biotechnology, University of Calicut, Malappuram, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2783-91

2783-2791

1540

401

20.

FORMULATION AND EVALUATION OF IN-SITU NASAL GEL OF MONTELUKAST SODIUM FOR THE EFFECTIVE TREATMENT OF ASTHMA

In this research work an attempt was made to formulate and evaluate in-situ gel for the intranasal delivery of montelukast sodium for the effective treatment of asthma. Thermally gelling in-situ gel formulations for nasal administration were prepared by using polymers such as poloxamer 407 and HPMC K4M in varying concentrations by using cold method. The formulated in-situ gels were evaluated for c...

S. Durgapal, M. Rana , S. Mukhopadhyay, A. J. Rana, L. Goswami and S. Joshi *

Department of Pharmaceutical Sciences, Kumaun University, Nainital, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2792-99

2792-2799

1989

442

21.

APPLICATION OF DOE AND STATISTICAL ANALYSIS FOR DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD FOR CHLROHEXIDINE GLUCONATE AND CETRIMIDE IN ITS BULK AND PHARMACEUTICAL DOSAGE FORMS

The present work includes development of analytical method for simultaneous estimation of Chlorhexidine gluconate and Cetrimide by RP-HPLC method. The chromatographic conditions were successfully optimised for the separation of Chlorhexidine gluconate and Cetrimide by using Hypersil BDS C18 column (4.6 × 150 mm) 5µ, flow rate of 0.8 ml/min, mobile phase ratio of (30:55:15 v/v/v) ACN: methanol: p...

S. J. Rajput * and M. A. Sathe

Faculty of Pharmacy, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2800-06

2800-2806

1352

439

22.

COMPARATIVE PHARMACOGNOSTIC EVALUATION AND STANDARDIZATION OF CAPSICUM ANNUUM L. (RED CHILI)

Present study includes the detailed pharmacognostic evaluation in terms of macroscopic and microscopic study along with physicochemical, phytochemical and fluorescence analysis of Capsicum annuum L., an annual spice and member of family Solanaceae, commonly known as red chili. The pharmacognostic studies provide comprehensive data not only in the identification but at the same time is an excellent...

N. Shaheen, S. Imam, S. Abidi, R. A. Sultan, I. Azhar and Z. A. Mahmood *

Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan.

DOI: 10.13040/IJPSR.0975-8232.9(7).2807-17

2807-2817

1149

409

23.

FORMULATION, OPTIMIZATION AND IN-VITRO EVALUATION OF DICLOFENAC SODIUM LOADED SUSTAINED RELEASE MATRIX TABLET CONTAINING BOTH NATURAL AND SEMI-SYNTHETIC POLYMERS

Objective: The persistence of this effort was to frame, evaluate and examine the impact of natural and semi-synthetic polymer in changing the release rates of matrix tablet loaded with diclofenac sodium. Materials and method: Matrix tablets of diclofenac sodium were made-up by varying the concentrations of both natural polymer i.e Guar gum and semi-synthetic polymer i.e HPMC K4M via straight compr...

U. Borah *, B. Dash, J. Chakraborty and B. Das

Girijananda Chowdhury Institute of Pharmaceutical Science, Azara, Guwahati, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2818-24

2818-2824

955

399

24.

AN INVESTIGATION OF IN-VITRO RELEASE OF RABEPRAZOLE SODIUM FROM PULSATILE RELEASE TABLETS CONTAINING HPMC-EC BLEND AS TIME LAGGED PRESS COATING

To develop new pulsatile release tablets of Rabeprazole sodium (RS), that can suppress drug release in stomach and release the drug rapidly after a predetermined lag time for about 4 h in intestine, a multiple unit dosage forms was designed that contain, drug-containing core, a coating to achieve time lag in drug release and an outermost acid resistant enteric coating. Time lagged press coating wa...

S. Chauhan, N. Nainwal *, T. Bisht and V. A. Saharan

Department of Pharmaceutics, School of Pharmaceutical Sciences, Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences and Research, Balawala, Dehardun, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2825-31

2825-2831

961

381

25.

DEVELOPMENT AND CHARACTERIZATION OF BILAYER TABLET CONTAINING TRAMADOL AND PREGABALIN AS A GASTRIC BUOYANT DRUG DELIVERY SYSTEM FOR COMBINATION PHARMACOTHERAPY OF NEUROPATHIC PAIN

Experiments were performed to design, develop and characterize bilayer buoyant tablets with Tramadol (TH), immediate release layer and Pregabalin (PGB), sustained release layer. Super disintegrants like crosscarmellose sodium and sodium starch glycolate, for IR layer where as Hydroxypropyl methylcellulose (HPMC-K4M, HPMC-K100M) and sodium carboxymethyl cellulose, as sustaining polymers for SR laye...

S. Kamble * and B. Poul

School of Pharmacy, Swami Ramanand Teerth Marathwada University, Nanded, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2832-41

2832-2841

1134

488

26.

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING METHOD FOR THE SIMULTANEOUS ESTIMATION OF ELBASVIR AND GRAZOPREVIRIN PHARMA-CEUTICAL DOSAGE FORMS BY RP-HPLC

The present study aimed to develop and validate stability indicating method for the simultaneous determination of Elbasvir and Grazoprevir in its pharmaceutical dosage form using RP-HPLC. Chromatographic separation was done with Discovery C18 (250 mm × 4.6 mm, 5 µ) column using 0.1% ortho-phosphoric acid (OPA) and acetonitrile in the ratio 50:50% v/v as mobile phase on isocratic mode. The column...

G. Ashok * and S. Mondal

Department of Pharmaceutical Analysis and Quality Assurance, Faculty of Pharmacy, Gland Institute of Pharmaceutical Sciences, Kothapet, Medak, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2842-46

2842-2846

948

358

27.

BACTERICIDAL SCREENING AND ESTIMATION OF FREE RADICAL SCAVENGING ACTIVITY OF FRUTICOSE LICHEN CLADONIA SCABRIUSCULA DELISE (NYL.) FROM GOPESHWAR, UTTARAKHAND, INDIA

Lichens came as a consortium of two distinct and dissimilar components- the mycobiont and the phycobionts, which were defined as a composite organism. Lichen vegetation in India is dominated by more than 2500 species. Lichen secondary metabolites specially the phenolics, depsides and depsidones are unique in their origin and are found nowhere else. Much attention has been paid on the biological ro...

A. Pandey *, A. Qidwai, M. Pandey, R. Kumar, S. K. Shukla and A. Dikshit

Biological Product Lab, Department of Botany, University of Allahabad, Allahabad, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2847-51

2847-2851

821

302

28.

CONVENTIONAL AND MICROWAVE ASSISTED SYNTHESIS OF SOME NEW DERIVATIVES OF COUMARIN CONTAINING PYRAZOLINE AND INVESTIGATION OF THEIR ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES

Pyrazoline derivatives, being used as potential medicinal agents, 3-Acetyl-2H-chromen-2one (I) was prepared by Knoevenagel condensation of salicyladehyde with ethylacetoacetate in presence of piperidine. A series of 3-[(2E)-3-substituted-prop-2-enoyl]-2H-chro men-2-one derivatives (II a-h) were prepared by Claisen-Schmidt condensation of 3-acetyl coumarin with aromatic aldehydes. Treatment of 3-su...

A. S. Lunkad * and R. L. Sawant

SCSSS’s Sitabai Thite College of Pharmacy, Pune-Nagar Bypass, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2852-58

2852-2858

928

362

29.

KNOWLEDGE AND ATTITUDE OF PRIMARY CARE PHYSICIANS TOWARD USE OF HERBS AS MEDICINE IN AL-WAZARAT HEALTH CENTER, PRINCE SULTAN MILITARY MEDICAL CITY, RIYADH, SAUDI ARABIA

Introduction: Herbs are the second most commonly used form of complementary and alternative medicine by public. The uses of medicinal herbs continue to increase worldwide. However, clinicians generally have limited knowledge and confidence about using of herbs in medicine. Therefore, this research aimed to assess the level of knowledge and attitude of primary care physicians toward use of medicina...

D. A. Al-Omaim *, G. Al-Arfaj and M. A. F. Abbas

Department of Medicine, Family and Community, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

DOI: 10.13040/IJPSR.0975-8232.9(7).2859-68

2859-2868

981

363

30.

EFFECT OF METHYL PARATHION (AN ORGANOPHOSPHATE) ON BIOCHEMICAL CONTENTS OF FRESH WATER CAT FISH HETEROPNEUSTES FOSSILIS (BLOCH)

The present work was planned to study the effect of methyl parathion an organophosphate compound (OP) on biochemical contents of fresh water cat fish Heteropneustis fossilis. The exposure of fish to the sub-lethal concentrations of the toxicant methyl parathion was investigated and the variations were observed in biochemical contents in different tissues of the fish i.e. gill, liver, intestine, mu...

T. B. Rao, K. Thirupathi and Y. Venkaiah *

Department of Zoology, Kakatiya University, Waranagal, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2869-74

2869-2874

932

338

31.

DESIGN OF EXPERIMENT IN THE BIO-ANALYTICAL DETERMINATION OF QUETIAPINE FUMARATE IN HUMAN PLASMA BY A RP-HPLC METHOD

A new, simple, sensitive, accurate and precise RP-HPLC method was developed for the estimation of quetiapine fumarate in human plasma. Full factorial design was used for the optimization of an extraction method. The main effect of volume of deproteinating agent, speed of centrifugation, time of centrifugation and temperature of centrifugation was found to be significant at P<0.0001 on all the r...

S. D. Dalvi *, R. K. Nanda and S. S. Chitlange

Department of Pharmaceutical Chemistry, Marathwada Mitramandal’s College of Pharmacy, Kalewadi, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2875-82

2875-2882

1037

339

32.

EXTRACTION AND CHARACTERISATION OF MUCILAGE FROM THE LEAVES OF HIBISCUS ROSA-SINENSIS LINN. (MALVACEAE)

Plant mucilages have found wide application in food, pharmaceutical and cosmetic industries. Hence, it would be worthwhile to characterise the physical and chemical attributes of mucilages from commonly available plants for their beneficial utilization. Hibiscus rosa-sinensis Linn. (Family Malvaceae), widely grown as an ornamental throughout the tropics and subtropicsis a good source of mucilage. ...

R. M. Vignesh * and B. R. Nair

Department of Botany, University of Kerala, Kariavattom, Thiruvananthapuram, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2883-90

2883-2890

2589

548

33.

EVALUATION OF THE EFFECT OF TYLOSIN (MACROLIDE ANTIBIOTICS) ON MURINE TOXOPLASMOSIS

Toxoplasmosis is a parasitic disease with global prevalence that is caused by a unicellular organism called Toxoplasma gondii. Given the high prevalence of the disease in the country, particularly in pregnant women, and severe complications of the disease for the fetus, congenital type, the disease consequences for patients taking medications that suppress the immune system as well as side effects...

Q. Asgari, M. F. Madan, S. Alipour * and S. N. Shahabadi

Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

DOI: 10.13040/IJPSR.0975-8232.9(7).2891-96

2891-2896

873

322

34.

DEVELOPMENT AND VALIDATION OF HPLC METHOD FOR DETERMINATION OF CERITINIB IN RABBIT PLASMA USING PDA DETECTOR

A rapid, sensitive and reproducible HPLC method was developed and validated for the quantification of Ceritinib in rabbit plasma using PDA detector at wave length 264 nm. The method was developed using Dasatinib as internal standard (IS). Ceritinib is a selective and potent inhibitor of anaplastic lymphoma kinase (ALK) indicated in the treatment of non-small cell lung cancer (NSCLC). The Ceritinib...

M. S. V. Sakuntala *, M. W. Carey and A. L. Rao

School of Pharmaceutical Sciences, JNTUK, Kakinada, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2897-04

2897-2904

1079

336

35.

FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS OF PROPRANOLOL PREPARED USING NATURAL POLYMER

Propranolol is beta-blocker and it is widely used in the management of hypertension. Propranolol is used to treat tremors angina, hypertension, heart rhythm disorder and other heart or circulatory conditions. The mucoadhesive buccal tablets of propranolol were papered by wet granulation method using natural polymer like Vigna mungo powder. The compatibility studies of drug and excipient were perfo...

G. M. Milind *, G. Yogesh and A. Yadav

Department of Pharmaceutics, Gourishankar Institute of Pharma-ceutical Education and Research, Limb Satara, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2905-13

2905-2913

1880

403

36.

FORMULATION AND EVALUATION OF SUSTAINED RELEASE TABLETS OF REPAGLINIDE USING HYDROPHILIC NATURAL AND SYNTHETIC POLYMERS

Repaglinide is used in the treatment of type 2 Diabetes mellitus and has very short half life. The patient compliance can decrease when larger doses are administered two to three times a day. Sustained release formulation which maintains a plasma level of 8-10 h might be recommended for daily administration of repaglinide. The main objective of the present study was to develop sustained release fo...

M. S. Reddy * and S. Archana

Centre for Pharmaceutical Sciences, Institute of Science and Technology, JNTUH, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2914-20

2914-2920

1415

427

37.

GC-MS ANALYSIS OF ANTI-MICROBIAL COMPOUNDS FROM ANTHERAEA MYLITTA COCOONS

The architecture of cocoons and the chemical compounds present in the cocoons play crucial role to provide protection of the pupae during metamorphosis. Insects spin a silk web as cocoon to facilitate protection and ensuring proper inner environment inside the cocoon during the metamorphosis. Such cocoons are equipped with a variety of chemical compounds which include antibacterial, antifungal, in...

M. S. I. Ahamad and S. K. Vootla *

Department of Biotechnology and Microbiology, Karnatak University, Dharwad, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2921-26

2921-2926

1023

340

38.

FORMULATION AND EVALUATION OF NANOEMULSION FOR ENHANCED BIOAVAILABILITY OF ITRACONAZOLE

Nanoemulsions are the novel drug delivery system which allows sustained or controlled release of drug, biological active ingredient and genetic material. Nanoemulsion is a system consisting of oil, surfactant and an aqueous phase, which is an isotropically clear and thermo-dynamically or kinetically stable liquid solution, usually with droplet diameter within the range of 10 - 500 nm. Nanoemulsion...

J. Suyal *, G. Bhatt and N. Singh

Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2927-31

2927-2931

1658

620

39.

TOPSIS ANALYSIS FOR THE PREDICTION OF DIABETES BASED ON GENERAL CHARACTERISTICS OF HUMANS

Worldwide diabetic patients are very common. This paper studies spread of diabetes in human living in Lahore, Pakistan. Data is collected from two local hospitals of Lahore and TOPSIS is applied to draw the results of the study. The study points out the people who are more likely to have diabetes due to various parameters like age, weight, height, body mass index (BMI), systolic blood pressure (SB...

M. Zulqarnain, F. Dayan * and M. Saeed

Department of Mathematics, University of Management and Technology, Lahore, Pakistan.

DOI: 10.13040/IJPSR.0975-8232.9(7).2932-39

2932-2939

817

268

40.

INCREASING COMPLEX FORMATION OF WEAK ACID DRUG WITH ION EXCHANGE RESIN

Functionality of Ion Exchange Resin (IER) mainly depends on solubility and degree of ionization and molecular weight of drug. For this reason the application of IER is limited to only strong acidic and basic drugs or drug existing as salt; not for weak acidic and weak basic drugs due to their low ionization properties. If we increase the ionization of weak acid and bases, then application of IER w...

A. K. Sahoo * and A. V. Gothoskar

Shri Venkateshwara University, Rajabpur, Gajraula, Amroha, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2940-46

2940-2946

1017

299

41.

ANTIOXIDANT POTENTIAL OF PHLOROGLUCINOL; AN IN-VITRO APPROACH

Phloroglucinol is a polyphenol and a component of phlorotannins belonging to the Laminariaceae family. Phloroglucinol has many positive effects on health. The present study was aimed to evaluate the antioxidant potential of phloroglucinol by comparing it with Standard antioxidant viz, ascorbic acid. The antioxidant potential of phloroglucinol was estimated using free radicals such as 1, 1-diphenyl...

I. Archana and K. Vijayalakshmi *

Department of Biochemistry, Bharathi Women’s College, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2947-51

2947-2951

979

300

42.

AN INVESTIGATION ON THE TYPE I ANTIDIABETIC ACTIVITY OF METHANOLIC EXTRACT OF MARINE ALGAE, GRACILARIA EDULIS AND SARGASSUM POLYCYSTUM

The objective of this study was to evaluate the antidiabetic activity of methanolic extract of marine algae Sargassum polycystum (MSP) and Gracilaria edulis (MGE) in STZ induced diabetes in rats for Type I diabetic mellitus. The marine algae SP and GE were dried under shade and then powdered, and extracted with methanol. Preliminary phytochemical studies and acute toxicity studies were also carrie...

R. Koneri, D. K. Jha and M. G. Mubasheera *

Department of Pharmacology, Karnataka College of Pharmacy, Bangalore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2952-59

2952-2959

1015

396

43.

ACUTE TOXICITY OF HYDROXYUREA IN MALE ALBINO MICE

This study was carried out to investigate the acute oral toxicity LD50 of an anti-neoplastic and a chemotherapeutic agent hydroxyurea in male albino mice by using up α Down method. The result revealed that LD50 of hydroxyurea was (7868.5 mg/kg. b.w). Orally after 24 h of exposure. That’s mean it is slightly toxic agent. To study the effect of lethal doses of hydroxyurea on the some of blood par...

A. I. Al-ameedi *, M. M. Al-Ani and B. S. Sahib

Department of Physiology Pharmacology, Collage of Veterinary Medicine Al-Qasim Green University, Iraq.

DOI: 10.13040/IJPSR.0975-8232.9(7).2960-64

2960-2964

960

324

44.

METHOD DEVELOPMENT AND VALIDATION OF VILDAGLIPTIN AND METFORMIN HCl IN PHARMACEUTICAL DOSAGE FORM BY REVERSE PHASE–HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (RP-HPLC)

Determination of the anti-diabetic drugs vildagliptin and metformin is wildly used to validate drug efficiency in diabetic patients. Here we describe a new and simple chromatographic method to analyze both drugs simultaneously in their commercial pharmaceutical dosage forms. A reverse Phase-high performance liquid chromatography (RP-HPLC) separation method was applied using an Xterra C18 column (2...

W. A. Dayyih *, M. Hamad, E. Mallah, A. A. Dayyih, R. Awad, Z. Zakaria and T. Arafat

Department of Pharmaceutical Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy and Medical Sciences, University of Petra, Amman, Jordan.

DOI: 10.13040/IJPSR.0975-8232.9(7).2965-72

2965-2972

2281

461

45.

SCREENING AND MOLECULAR IDENTIFICATION OF POTENTIAL EXOPOLY-SACCHARIDES (EPSs) PRODUCING MARINE BACTERIA FROM THE BHAVNAGAR COAST, GUJARAT

Marine environment is a complex habitat defined by a wide fluctuation in conditions such as pH, temperature, nutrient availability, osmotic pressure and salinity. Because of these various extreme environmental conditions, it harbors varieties of biodiversity such as bacteria, algae, fungi, coral reefs and sea weeds, as compared to terrestrial environment. For adaptation in these conditions marine ...

P. J. Shukla and B. P. Dave *

Department of Life Sciences, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2973-81

2973-2981

1193

349

46.

DEVELOPMENT OF HPLC METHOD FOR DETERMINING THE FOREIGN IMPURITIES IN THE SUBSTANCE OF CARBOREN

A High-Performance Liquid Chromatography (HPLC) technique has been developed for the determining of foreign impurities in the parent substance of carboren. We have proposed the most sensitive, selective and also the universal HPLC method to be used, which would allow to conduct the qualitative and quantitative analysis under the same conditions so that to determine foreign impurities in the substa...

N. L. Bereznyakova *, S. V. Baiurka, A. V. Berezniakov, V. D. Yaremenko and L. A. Bobritskaya

Department of Medicinal Chemistry, National University of Pharmacy, Kharkiv, Ukraine.

DOI: 10.13040/IJPSR.0975-8232.9(7).2982-85

2982-2985

1041

286

47.

SOCIAL AND BIOLOGICAL FACTOR OF TYPE 2 DIABETES MELLITUS

Diabetes mellitus is reaching potentially epidemic proportions in India. The level of morbidity and mortality due to diabetes and its potential complications are enormous and pose significant healthcare burdens on both families and society. In this study 400 blood serum samples were collected from various laboratories and diabetic centre in and around Tirupur, Tamil Nadu, India. Blood glucose leve...

R. Gopika *, G. Senthilkumar, E. S. Karthy, M. Revathi and A. Paneerselvam

A. V. V. M. Sri Pushpam College (Autonomous), Poondi, Thanjavur, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2986-89

2986-2989

1382

368

48.

EVALUATION OF IN-VITRO ANTIOXIDANT AND ANTIPLASMODIAL ACTIVITIES OF THE ACETONE EXTRACT OF CRINUM JAGUS BULBS (LILIACEAE) LINN.

This study evaluated the acetone extract of Crinum jagus bulbs for its antioxidant, and antiplasmodial properties. The bulbs of Crinum jagus are used in traditional medicine for various ailments. The antioxidant activity of the extract was evaluated using DPPH and nitric oxide free radical scavenging assay. The antiplasmodial activity (suppressive, prophylactic and curative activity) was evaluated...

O. A Shorinwa *, O. O. Ebong, A. W. Obianime and I. M. Siminialayi

Department of Experimental Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Port Harcourt, Rivers State, Nigeria.

DOI: 10.13040/IJPSR.0975-8232.9(7).2990-98

2990-2998

858

318

49.

STUDY ON SAFETY AND EFFICACY OF DIFFERENT MODALITIES IN THE POST-OPERATIVE PAIN MANAGEMENT IN A TERTIARY CARE TEACHING HOSPITAL

ABSTRACT: Background: Postoperative pain control is an important part of effective postoperative care. However, 30 - 80% of postoperative patients complain about moderate to severe post-surgical pain as a result of the surgical procedure or a pre-existing disease. Aim: To assess the safety and efficacy of different modalities of postoperative pain management in post surgical wards of a tertiary ca...

P. Thennarasu *, N. V. Rani, G. Ragesh and G. Vidhya

Department of Pharmacy Practice, Faculty of Pharmacy, Sri Ramachandra Medical College and Research Institute (Deemed to be University), Porur, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2999-04

2999-3004

970

292

50.

IN VITRO ANTIMICROBIAL SCREENING OF MEDICINAL PLANTS AGAINST CLINICAL AND PHYTOPATHOGENIC BACTERIA AND FUNGI

The positive results of screening medicinal plants for antimicrobial activity forms primary platform for phytochemical and pharmacological studies in future. The work was undertaken to evaluate the antimicrobial activity of four medicinal plants viz., Sesbania grandiflora, Epiphyllum oxypetalum, Nyctanthes arbor-tristis, and Vetiveria zizanioides. Leaves were extracted using water and ethanol as s...

S. P. Purushotham * and N. Anupama

P. G. Department of Botany, Maharani’s Science College for Women, Mysuru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3005-14

3005-3014

967

353

51.

QUANTITATIVE DETERMINATION OF PIPERACILLIN BY IODOMETRIC METHOD USING POTASSIUM PEROXOMONOSULFATE

Kinetics and stoichiometry S-oxidation reaction of sodium piperacillin by means of potassium hydrogen peroxomonosulfate in aqueous solutions using iodometric titration were studied. Zopercin® – powder in vials for piperacillin injection solution in the combined form with tazobactam (piperacillin 4.0 g and tazobactam 0.5 g) was used for analysis. A new iodometric method for quantitative determin...

S. P. Karpova *, M. Y. Blazheyevskiy, O. O. Mozgova, Y. Y. Serdiukova, M. M. Ivashura and I. Y. Petukhova

Department of Physical and Colloid Chemistry, National University of Pharmacy, Pushkinska Street, Kharkiv, Ukraine.

DOI: 10.13040/IJPSR.0975-8232.9(7).3015-19

3015-3019

1365

389

52.

A PRELIMINARY STUDY ON TOTAL PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITIES OF CALYCOPTERIS FLORIBUNDA ROOT EXTRACTS

We evaluated the total phenolic acid content and antioxidant activity of methanolic and aqueous extracts of Calycopteris floribunda roots. Antioxidant activity of the extracts was determined using Reducing Power Assay and Total Antioxidant Capacity (TAC) assays. Preliminary phytochemical analysis of the extracts revealed the presence of various phytochemicals. The total phenolic content of the ext...

A. B. Vantamuri *, Y. B. Sounshi, O. Kotresh and S. S. Dodamani

Department of Biotechnology, Karnatak Science College, Dharwad, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3020-23

3020-3023

797

339

53.

ISOLATION AND CHARACTERIZATION OF NATURAL PRODUCT COMPOUNDS FROM RHIZOMES OF CYPERUS ROTUNDUS LINN.

Background: Cyperus rotundus Linn. is a traditional medicinal plant appearing among Indian, Chinese and Japanese natural drugs, used for the treatment of spasms stomach disorder and also used as anti-inflammatory, antimalarial, hypotensive, antipyretic, anthelmintic, hepatoprotective agent. Rhizomes of C. rotundus have been used in ancient medicine in India for fever, dysentery, pruritis, pain, vo...

T. C. Sharma, A. K. Sharma *, S. K. Meena, M. P. Dobhal and M. C. Sharma

Department of Chemistry, Jagan Nath University, Jaipur, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3024-28

3024-3028

1077

367

54.

ANTI-MICROBIAL AND ANTI-TUBERCULAR ACTIVITY EVALUATION OF NEWLY SYNTHESIZED ZINC COMPLEXES OF AMINOTHIOPHENE SCHIFF BASES

Tridentate Schiff bases were obtained in succession from the condensation of ethyl 2-amino-5,6-dihydro-4H-cyclopenta [b] thiophene-3-carboxylate and different aryl aldehydes in 1:1 molar ratio. Zinc chloride complexes of these new aminothiophene Schiff bases were prepared in 1:1 metal: ligand stichometry. These complexes were characterized using IR, UV-Visible, elemental analysis and molar conduct...

G. More, S. Bootwala *, S. Shenoy, J. Mascarenhas and K. Aruna

Department of Chemistry, Wilson College, Girgaon Chowpatty, Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3029-35

3029-3035

1033

369

55.

ZINC AND COPPER LEVELS AND THEIR CORRELATION WITH POLYCYSTIC OVARY SYNDROME BIOCHEMICAL CHANGES

Background: Multiple logistic regression analysis of several metabolic variables between polycystic ovary syndrome and control groups revealed that zinc level was the most important variable to predict polycystic ovarian syndrome. Objective: This study was designed to illustrate the correlation between zinc and copper levels with the biochemical changes associated with polycystic ovary syndrome. M...

B. H. Khalaf *, M. H. Ouda, H. S. Alghurabi and A. S. Shubbar

Department of Pharmacology and Toxicology, College of Pharmacy, University of Kerbala, Kerbala, Iraq.

DOI: 10.13040/IJPSR.0975-8232.9(7).3036-41

3036-3041

2367

366

56.

COMPARATIVE EVALUATION OF ANTIMICROBIAL EFFICACY OF TWO COMMERCIALLY AVAILABLE HERBAL AND NON-HERBAL (FLUORIDATED) TOOTHPASTES ON SALIVARY MICROBIAL COUNT: AN IN-VIVO STUDY

Dental caries is a complex disease which is expressed as an interaction between various factors including the host, agent, substrate and time. The interplay between the dental biofilm and oral microorganisms is an important feature for development of a cariogenic dental plaque. Formation of the biofilm needs to be controlled through regular brushing in order to prevent the development of caries an...

K. Patel *, S. Karkare, B. Pustake, D. Kothawade, S. Khedkar and S. Bote

Department of Pedodontics and Preventive Dentistry, MGV’s K.B.H Dental College and Hospital, Panchavati, Nashik, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3042-46

3042-3046

1187

333

57.

GC-MS ANALYSIS, ANTIBACTERIAL AND ANTICANCER ACTIVITIES OF BARK EXTRACT OF LANNEA COROMANDELICA (HOUTT.) MERR.

Lannea coromandelica is one of the important herbal plants well distributed in India. It is commonly called as Odiar, Gumphini in South India. It was extensively used by the tribes all over India to treat various diseases such as body pain, tooth ache, stomach ache, ulcers, sexual impotency. The aim of the present study was to evaluate the GC-MS analysis, antibacterial and anticancer activities of...

C. Sivaraj *, B. Pavithra, A. Srivastav and P. Arumugam

Natural Product Division, ARMATS Biotek Training and Research Institute, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3047-51

3047-3051

953

368

58.

EXTRACTION AND QUANTIFICATION OF PIGMENTS FROM INDIAN TRADITIONAL MEDICINAL PLANTS: A COMPARATIVE STUDY BETWEEN TREE, SHRUB AND HERB

Chlorophyll and carotenoids are important photosynthetic pigments found in higher plants, cyanobacteria and algae. Carotenoids are responsible for bright red, yellow and orange color in many fruits and vegetables. These two pigments play an important role in plant health. Chlorophyll and carotenoids are reported to contain anticancer properties. Chlorophyll and carotenoids protect skin and help in...

P. Ghosh, P. Das, R. Mukherjee, S. Banik, S. Karmakar * and S. Chatterjee

Department of Biotechnology, Techno India University, Kolkata, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3052-59

3052-3059

1907

431

59.

FORMULATION OF NICERDIPINE HYDROCHLORIDE INCLUSION COMPLEX FOR DISSOLUTION ENHANCEMENT

The purpose of this study was to improve the dissolution rate of poorly soluble Nicardipine hydrochloride with cyclodextrin complexation by using different techniques like physical mixing, solvent evaporation and kneading method. Nicardipine hydrochloride is a calcium channel blocker. It is belonging to BCS class - II having poor solubility and high permeability. It is used to treat Angina having ...

S. Makwana , R. Kharadi and S. Samova *

Department of Zoology, University School of Sciences, Gujarat University, Ahmedabad, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3060-65

3060-3065

904

364

60.

HPTLC FINGERPRINTING FOR SIMULTANEOUS QUANTIFICATION OF HARMINE, KAEMPFEROL, DIOSGENIN AND OLEIC ACID IN THE FRUIT EXTRACT OF TRIBULUS TERRESTRIS L. AND ITS FORMULATION

A simple, accurate and reproducible HPTLC method has been developed for the simultaneous quantification of diosgenin, oleic acid, harmine and kaempferol from the methanolic extract of fruits of plant Tribulus terrestris L. and its marketed formulation. The CAMAG HPTLC systems with winCATS software used for the analysis. Double development with mobile phase Toluene: Ethyl acetate: Formic acid: Glac...

V. V. Vaidya, P. L. Kondalkar *, M. A. Shinde and S. Gotmare

Department of Chemistry, Ramnarain Ruia College, Matunga, Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3066-74

3066-3074

1097

367

61.

DEVELOPING A TOOL FOR MEASURING KNOWLEDGE ABSORPTIVE CAPACITY AND ASSESSING ITS EFFECT ON INNOVATION PERFORMANCE OF IRANIAN PHARMACEUTICAL COMPANIES

Now a day’s establishing and sustaining competitive advantage depends on the effective development of Knowledge Absorptive Capacity (KAC) and innovations. This study evaluated the role of prior technical experiences in developing firm’s absorptive capacity and the contribution of this type of capacity to the firm’s innovation performance. In this study we designed a questionnaire to assess f...

E. Sanati, V. Varahrami, M. Davari, K. Keshavarz, A. Abdollahiasl, H. Madani and A. Kebriaeezade *

Pharmaceutical Management and Economics Research Center, Tehran University of Medical Sciences, Tehran, Iran.

DOI: 10.13040/IJPSR.0975-8232.9(7).3075-82

3075-3082

932

383

62.

PHYTOCHEMICAL AND TOXICOLOGICAL INVESTIGATION ON AQUEOUS EXTRACT OF POLYHERBAL PREPARATION

Polyherbal preparations (PHP) are   known to express high effectiveness in a vast number of diseases. In view of this, present investigation was carried out to identify phytochemical constituents of PHP, prepared from the aqueous extract of test plant powders of Mimusops elengi Linn., Strobilanthes barbatus Nees, Indigofera zollingeriana Miquel and Dillenia indica Linn. Phytochemical screening o...

R. Pasupula * and R. R. Pragada

Department of Pharmacology, St. Anns College of Pharmacy, Prtakasam, Vizianagaram, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3083-93

3083-3093

929

352

63.

IMMOBILIZATION AND ESTIMATION OF ACTIVITY OF YEAST CELLS BY ENTRAPMENT TECHNIQUE USING DIFFERENT MATRICES

Background: It becomes clear that living processes were based on the action of enzymes. Cell immobilization serves as a useful tool for the immobilization of intracellular enzymes. The purpose of study is to improve economically important processes by attaching the yeast cells to matrices. Methods: In this analytical study by using mixed models of matrices like (sodium alginate alone, sodium algin...

N. K. D. Devi * and A. S. S. Nagamani

KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).3094-99

3094-3099

1858

359