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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

Inclusion in Web of Science (Thomson Reuters) - ESCI
Projected Impact Factor (2017): 0.59 , SJR (2017): 0.14
Five-Year Projected Impact Factor: 1.83

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Volume 6 (2015) - Issue 2, February

Review Articles

 
Title
Views
PDF
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1.

HISTAMINE SUBTYPE 3 RECEPTOR ANTAGONISTS: CURRENT STATUS WITH FUTURE PROSPECTS IN DRUG DISCOVERY AND DRUG DEVELOPMENT

The  histamine  H3 receptor is  an  G protein-coupled  receptor that regulates neurotransmission  in  the  central  nervous  system  and plays a major role in cognitive and homeostatic functions. The third histamine receptor was discovered in 1983 by a traditional pharmacological approach, consisting of assessing the inhibitory effect of histamine on its own release from depolarized rat...

Shreya Singh and Satyendra K. Rajput*

Amity Institute of Pharmacy, Amity University, NOIDA, Uttar Pradesh-201303, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).502-09

502-509

4546

1590

2.

SOLID DISPERSION TECHNOLOGY: RECENT ADVANCEMENTS IN THE DELIVERY OF VARIOUS PHYTOCONSTITUENTS

Nature is an eminent source of potential therapeutic drugs, however; most of the herbal bioactives are left unexploited as precise remedies due to lack of appropriate formulation design and development. Pharmacological interventions of herbal molecules may often be limited due to insufficient solubility, bioavailability as well as instability aspects and it remains one of the most challenging face...

Rakesh Pahwa , Umang Kataria , A. C. Rana , Rekha Rao and Sanju Nanda*

Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak-124001, Haryana, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).510-20

510-520

3071

1857

3.

ADVANCED GLYCATION END PRODUCTS IN PROGRESSIVE COURSE OF DIABETIC NEPHROPATHY: EXPLORING INTERACTIVE ASSOCIATIONS

Diabetic nephropathy is a major complication of diabetes and the most common cause of end stage renal damage (E.S.R.D). Diabetic nephropathy is a leading cause of morbidity and mortality and its prevalence is continuously increasing in industrialized nations. Hyperglycemias, hyperlipidaemia and hypertension are considered to be the major risk factors implicated in the progression of nephropathy. P...

Augustin Kumar Bharti*, Amit Agrawal and Suraj Agrawal

Department of Pharmacology, Pt. J. N.M. Medical College, Raipur, 492001, Chhattisgarh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).521-28

521-528

2248

875

4.

NANOSPONGES – NOVEL EMERGING DRUG DELIVERY SYSTEM: A REVIEW

The advent of nanotechnology lead to invention of many dosage forms. Effective targeted drug delivery systems have been a dream for a long time, due to several major drawbacks, a practical approach has been developed for the formation of discrete functionalized particles, which have been termed as ‘Nanosponge’. The development of new colloidal carrier called Nanosponges has the potential to so...

Shastrulagari Shivani * and Kranthi Kumar Poladi

Samskruthi College of Pharmacy, Ghatkesar, Ranga Reddy- Dist-501301, Telangana, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).529-40

529-540

6087

2614

5.

CLINICAL EFFECTIVENESS OF GLUCOSAMINE AND CHONDROITIN SULPHATE IN TREATMENT OF OSTEOARTHRITIS

Osteoarthritis is a form of arthritis, and is the most common form of arthritis. Persons suffering from osteoarthritis have symptoms of pain, stiffness, decreased range of motion of affected joints. Although NSAIDS are the most commonly prescribed agents for this disorder but can cause of serious adverse effects. Two compounds Glucosamine and chondroitin which are extracted from animal products ha...

Fakhra Batool , Muhammad Sohail *, Fizah Ashraf , Beenish Rana , Fahad Mahmood and Sana Tanveer

Department of Pharmacy IUB Cosmetics Lab. Department of Pharmacy Khawaja Fareed Campus Islamia University Bahawalpur Pakistan

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).541-45

541-545

2551

897

6.

METHODS FOR DETERMINATION OF ANTIOXIDANT CAPACITY: A REVIEW

Antioxidants have become a vital part of our lives today. Antioxidants help neutralize or destroy “Reactive Oxygen Species” (ROS) or free radicals before they can damage cells. This paper focuses on types of damaging free radicals generated in metabolic processes and also gives an insight of mechanistic aspect of various in-vitro methods for evaluation of antioxidant capacity of plant metaboli...

Deepshikha Gupta

Department of Chemistry, Amity Institute of Applied Sciences, Amity University Uttar Pradesh, Sector 125, Noida-20130, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).546-66

546-566

7464

6229

7.

PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF IXORA: A REVIEW

Medicinal herbs used in modern medicine are occupying a very significant place as raw materials for important drugs. India officially recognizes over 3000 plants for their medicinal value. It is generally estimated that over 6000 plants in India are used in traditional, folk and herbal medicine. Traditionally Ixora is found to be useful for many ailments like hepatic disorder, cancer, microbial in...

Sunitha Dontha *, Hemalatha Kamurthy and Bhagavanraju Mantripragada

Malla Reddy College of Pharmacy, Maisammaguda, Dhullapally, Secunderabad, 500 014, Andhra Pradesh, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).567-84

567-584

12790

4774

Research Articles

 
Title
Views
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Cited
8.

EXPRESSION OF GLUCOSAMINE-6-PHOSPHATE ISOMERASE AND JACOB GLYCOPROTEIN DURING CULTURE OF ISOLATES OF ENTAMOEBA HISTOLYTICA

The glucosamine-6-phosphate isomerase and Jacob glycoprotein gene expression levels were assessed during E. histolytica excystation from the feces of five patients. Excystation was performed at 0, 24, 48 and 96 h in Robinson medium, and RNA was extracted from the cysts and trophozoites. cDNA was synthesized to amplify the genes using real-time RT-PCR. The results demonstrated differences according...

E. Jimenez-Cardoso,* MP. Crisostomo-Vazquez, L. Eligio- Garcia, VA. Marevelez- Acosta, P. Antonio- Cruz and A. Flores-Luna

Hospital Infantil de Mexico Federico Gomez, Laboratory of Parasitology Research, Dr. Márquez #162 Col. Doctores, 06720 México, D.F.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).585-90

585-590

2047

658

9.

EVENTUAL IMMUNOLOGIAL BENEFIT OF PHOSPHODIESTERASE IV INHIBITOR (ROLIPRAM) ON THE LUNG AND LENS AFFECTION INDUCED BY SELENIUM IN RATS: A PHARMACOLOGICAL, LIGHT AND SCANNING ELECTRON MICROSCOPE STUDY

The association between chronic bronchitis and cataract is debating. While some referred it to the corticosteroid therapy commonly prescribed to bronchitis, other named different immunological pathways that may be involved in this relationship. We tried to find out the possible immunological benefit of phosphodiesterase IV inhibition in these two common associated conditions. The rats were divided...

Omnyah A. El-Kharashi * and Abeer A. Abd El Samad

Pharmacology Department Facility of medicine Ain shams university, Egypt

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).591-03

591-603

1753

695

10.

REPEATED-DOSE TOXICOLOGICAL STUDIES OF HYDROALCOHOLIC EXTRACT OF LANNEA KERSTINGII ENGL AND K. KRAUSE (ANACARDIACEAE) AND IDENTIFICATION OF TOXICITY MECHANISMS

Lannea kerstingii Engl. & K. Krause stem bark (Anacardiaceae) is used to treat anaemia, malaria, infections and Burili ulcer. The antioxidant, antihelmintic and trypanocidal properties have been demonstrated using appropriate in vitro and in vivo assays. But the effective doses have demonstrated toxic effects such as a significant decrease of body weight of the experimental animals. This work ...

Aboudoulatif Diallo *, Kwashie Eklu-Gadegbeku , Amegnona Agbonon , Kodjo Aklikokou , Gado Napo-Koura , Edmond Creppy and Messanvi Gbeassor

Department of Toxicology University of Lome (Togo) Faculty of Sciences, University of Lome (Togo) P.O. Box 216 lomé05

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).604-11

604-611

2030

739

11.

PREVALENCE AND CAUSES OF SELF-MEDICATION IN PREGNANT WOMEN REFERRING TO HEALTH CENTERS IN SOUTHERN OF IRAN

Objective: The self-medication phenomenon is one of the acute health problems particularly in women and as encountering a sensitive period such as pregnancy is of critical importance. The present study has been conducted to determine the prevalence and causes of this phenomenon in the pregnant women in the city of Ahwaz, located in the west south of Iran. Methods: In this descriptive-analytical st...

Porandokht Afshary, Solmaz Mohammadi * Shanaz Najar , Zahra Pajohideh and Hamed Tabesh

Department of Nursing and Midwifery, Ahvaz jundishapur University of Medical Sciences, Ahvaz, Iran

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).612-19

612-619

2739

893

12.

PHYTOCHEMICAL SCREENING, CYTOTOXIC AND CNS DEPRESSANT ACTIVITIES OF HOLARRHENA ANTIDYSENTERICA LEAVES AND SEEDS

Methanolic extract of leaves and seeds of Holarrhena antidysenterica was appraised individually to investigate the cytotoxic activity and CNS depressant activity of the leaf extract was observed adopting both open field test and hole cross test. Phytochemical screening with the leaf extract only, suggested the presence of alkaloids, cardiac glycoside, steroids, flavonoids, tannins and saponin. Bri...

U. J. Nahar , M. M. R. Bhuiyan , A.N.M Samsudduzah , M. R. Uddin and Z. Maryam *

Lecturer, Department of Pharmacy, State University of Bangladesh 77, Dhanmondi, Dhaka-1205, Bangladesh.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).620-23

620-623

2139

1101

13.

IN-VITRO EVALUATION OF SHEA BUTTER-BASED NYSTATIN MICROPARTICLES

Nystatin, an antifungal drug for mucosal infections has a large dosing frequency and is rapidly inactivated by acids. In order to increase drug stability and reduce dosing frequency and reduce dosing frequency and gastric irritation, formulation into inert lipid matrices as solid lipid microparticles may be utilized. The formulations were done from Shea butter extract using either Tween 20 or Twee...

H. C. Nwuke , I. T. Nzekwe *, C. O. Agubata , A. A. Attama , K. C. Ofokansi , O. Okorie , V. C. Okore and C. O. Esimone

Department of Pharmaceutics and Pharmaceutical Technology, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).624-29

624-629

1608

1108

14.

COMPARATIVE STUDY OF ANTIBIOTICS FOR THEIR ANTIMICROBIAL SUSCEPTIBILITY IN CLINICAL ISOLATES

Objective: Antibiotics resistance patterns for many bacteria have changed significantly; causing poor clinical outcomes. The objective of the study was to measure the susceptibility of different antibiotics against specific clinical isolates for surveillance purpose. Method: Kirby-Bauer disc diffusion method was used to evaluate the susceptibility pattern of four antibiotics (commercially availabl...

Farheen Zaheer , Shahnaz Usman *, Sakina Fatima and Muhhammad Mohtasheem Ul Hasan

Department of pharmaceutics Rak College of pharmaceutical sciences, RAKMHSU, Ras Al Khaimah, UAE. Postal code: 11172

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).630-35

630-635

2560

759

15.

HOMOLOGY MODELLING, SECONDARY STRUCTURE PREDICTION AND PHYLOGENETIC COMPARATIVE ANALYSIS OF PHOSPHOLIPASE A2FROM DIFFERENT ORGANISMS

Phospholipase A2 is the enzyme that catalyzes the hydrolysis of the sn-2 fatty acyl bond of phospholipids, liberating free fatty acids and lysophospholipids. These enzymes are found in mammalian tissues, insects, reptiles, urochordates, invertebrates and echinoderms. Some of the PLA2 are toxic in nature. Venom from snakes and insects is largely composed of melittin, which is a stimulant of PLA2...

K. Aparna*, C. Joyce Priyakumari and J Gladies Kezia

Bioinformatics Centre of BTIS net, Madras Christian College, Chennai, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).636-44

636-644

1509

591

16.

CONCEPTION OF A POTENT DRUG THROUGH TOXICITY AND PHARMACOPHORE STUDY FOR INHIBITING CD 1 INVOLVED IN CANCER BY MOLECULAR DOCKING STUDIES

Cancer is a class of disease, where the cells uncontrollably divide without any control over cell cycle and cell division. Various factors contribute to cause of cancer in many ways. Ultimately the cancer cell proliferates without control over cell cycle. Many factors involve in cell cycle amongst that one of the ideal target is Cyclin D1 which couples with cyclin dependent kinase 4, phosphorylate...

Katarikonda Sudhakar

Department of Pharmacology, Vagdevi College of Phramacy and Research Centre, Brahmadevam, Nellore - 524346, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).645-51

645-651

1509

924

17.

GREEN SYNTHESIS OF NANOPARTICLES AND THEIR ANTIBACTERIAL ACTIVITY AGAINST PATHOGENIC BACTERIA

The present study investigated the phytochemical analysis of the major bioactive constituents of medicinal important plant of Punica granatum peels in its aqueous extract and green synthesis of silver nanoparticles and their evaluation for antibacterial activity. Flavonoid, phenol & tannins, carbohydrates, glycosides and etc were highly concentrated in the peels extract. The synthesis and char...

Vijay Laxmee Mishra and Richa Sharma

Department of Biotechnology and Allied Sciences, Jayoti Vidyapeeth Women’s University, Jharna, Mahla – Jobner Link Road, Jaipur- Ajmer Express Way, Jaipur -303122, Rajasthan, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).652-59

652-659

2285

1416

18.

SLEEP QUALITY IN END-STAGE RENAL DISEASE PATIENTS ON MAINTENANCE HEMODIALYSIS: A SIX MONTH PROSPECTIVE SURVEY

Objective: The aim of this study was to evaluate the sleep quality and to identify risk factors for poor sleep quality in hemodialysis population. An additional aim of the study was to identify number of patients treated for their sleep problems. Method: 126 patients undergoing hemodialysis treatment were enrolled into the study. Subjective sleep quality was measured using Pittsburgh Sleep Quality...

V.B. Menon , P. Alla , S. Madhuri , S.R. Sanathan *, M.S. Shetty and D. Ram

Lecturer, Department of Pharmacy Practice, JSS College of Pharmacy, JSS University and Clinical Pharmacist, JSS Hospital, Mysore- 570004, Karnataka, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).660-68

660-68

2004

660

19.

DOCTOR’S PRESCRIBING TRENDS OF ANTIBIOTICS FOR OUT PATIENTS IN BANGLADESH: A CROSS-SECTIONAL HEALTH SURVEY CONDUCTED IN THREE DISTRICTS

Objectives: The aim of this study was to analyze and evaluate the practitioners’ prescribing habits of antibiotics in three cities of Bangladesh. Methods: A cross sectional health survey with manual data collection was carried out with a standardized questionnaire over three month period at the three cities Rajshahi, Jessore and Comilla in Bangladesh. The collected data was subjected to simple d...

Mohitosh Biswas *, Debendra Nath Roy , Md. Mahbubur Rahman , Monirul Islam G.M. Masud Parvez , Md.Uzzal Haque , Abdullah Al Ehsan Shahriar , Md. Sabbir Ahmed and Sayeman Islam Niloy

Lecturer Department of Pharmacy University of Rajshahi Rajshahi-6205, Bangladesh.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).669-75

669-675

1944

1149

20.

QUANTIFICATION OF DIOSGENIN IN EXTRACTS AND FORMULATIONS CONTAINING SOLANUM NIGRUM

A reversed phase high performance liquid chromatography coupled with diode array detector (HPLC–DAD) was developed and validated to quantitate diosgenin in berries of Solanum nigrum using C18 analytical column as stationary phase and acetonitrile: water (92: 08, v/v) as mobile phase. The flow rate of mobile phase was kept at 1.0 ml/min. Column oven temperature was set at 25 0C. The method was fo...

Sonal Desai , Pratima Tatke * and S. Y. Gabhe

Professor of Pharm.Chem. C. U. Shah College Of Pharmacy, S. N. D. T. Women’s University, Sir Vithaldas Vidhyavihar, Juhu Road, Santacruz (W), Mumbai-400 049, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).676-81

676-681

1700

1009

21.

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ZALTOPROFEN AND PARACETAMOL IN COMBINED DOSAGE FORM BY ULTRAVIOLET SPECTROPHOTOMETRY

Two spectrophotometric methods are presented for the simultaneous estimation of Zaltoprofen (ZLT) and Paracetamol (PAR) in laboratory prepared mixture and pharmaceutical dosage form without prior separation. Method (1) is simultaneous equation method (Vierodt’s method); which depends on the fact that absorbance of a mixture is the sum of the individual absorbance of the components. Method (2) is...

N. K. Zahira * and P. N. Prasannakumaran

College of Pharmaceutical Sciences, Medical College, Thiruvananthapuram, Kerala - 695011, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).682-87

682-687

1726

926

22.

PHYTOCHEMICAL ANALYSIS AND ANTIFUNGAL ACTIVITY OF MOSS BRYUM CELLULARE AGAINST SOME PHYTOPATHOGENIC FUNGI

Bryophytes possess a pool of bioactive compounds with pharmacological activity. These plants have widely been used as medicinal plants since ancient times and are not infected by bacteria and fungi as they use chemical weapons in the form of secondary metabolites. In order to evaluate the antifungal activity of aqueous crude extract of Bryum cellulare (a moss) against the test fungi Curvularia lun...

G. S. Deora * and N. Guhil

Department of Botany, New Campus, Jai NarainVyas University, Jodhpur-342005 India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).688-91

688-691

2064

753

23.

IN-VITRO ANTIVIRAL ACTIVITY OF INDIAN MEDICINAL PLANTS TO ASIAN AND EAST CENTRAL SOUTH AFRICAN LINEAGE OF CHIKUNGUNYA VIRUS

Indian medicinal plants traditionally used for the treatment of viral infections with high fever, arthritis, inflammation were investigated for their in vitro antiviral activity against the Asian and East Central South African lineage of Chikungunya virus. In vitro cytotoxic assay of aqueous, aqueous ethanolic and ethanolic extracts of Alpinia   Galanga (L) Willd., Alpinia   Officinarum   Ha...

K. Sangeetha and S. Rajarajan*

PG & Research Dept of Microbiology & Biotechnology, Presidency College (Aut), Chennai, TN, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).692-97

692-697

1819

957

24.

SYNTHESIS AND TESTING OF METAL COMPLEXES OF QUINOXALINE BASED SCHIFF BASES FOR ANTIMICROBIAL AND ANTICANCER ACTIVITIES

The compound 3-chloro-2-hydrazine quinoxaline was condensed with 2-furaldehyde to derive a Schiff base 2-furaldehyde-2-(3-chloro-2-quinoxalinyl) hydrazone (FCCQH).The ligand and also its complexes with VO (IV), Cr (III), Mn (II), Fe (III), Co (II), Ni (II), Zn (II), and Pd (II) have been synthesized and characterized by elemental analysis, magnetic studies, thermal analysis, infrared spectra, UV-v...

Ravinder Manchal, Mamatha Kasula, Srujana Muthadi, K.V.N.G Kumari and Srihari Somu*

Department of Chemistry, Kakatiya University, Warangal, TS, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).698-04

698-704

1674

645

25.

PHARMACOGNOSTIC STANDARDIZATION OF MADHUCA INDICA LEAF AND STEM, AN IMPORTANT MEDICINAL PLANT

Objective: To evaluate the pharmacognostic characters of Madhuca indica J.F. Gmel leaf and stem an important traditional medicinal plant. Method: In the present investigation, pharmacognostic parameters like macroscopic and microscopic and powder characters of leaf and stem were studied. Preliminary phytochemical and physiochemical analyses were done by using reported methods. Fluorescent behavior...

Pooja Moteriya, Hemali Padalia, Tejas Rathod, Dishant Desai and Sumitra Chanda *

Phytochemical, Pharmacological and Microbiological Laboratory Department of Biosciences, Saurashtra University - Rajkot, 360 005, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).705-11

705-711

2121

918

26.

PHYTOCHEMICAL ANALYSIS AND ANTIBACTERIAL ACTIVITY OF DALBERGIA PANICULATA ROXB.

Methanolic extracts of leaf, bark, stem and root of D. paniculata were screened for phytochemicals and antibacterial activity against ten different pathogens. Various phytochemicals such as terpenoids, flavonoids, coumarins, saponins and tannins were found to be present. Leaf and bark extract exhibited maximum antibacterial activity against S. aureus, P. vulgaris and E. coli with MIC value of 2.5 ...

S. Chaitra, N. Naveen Kumar *, P. Shalini, R. Sindhu and K. M. Sharu Raj

Department of PG Studies and Research in Biotechnology, Government Science College, Bangalore 560 001, Karnataka, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).712-16

712-716

1654

1201

27.

DEVELOPMENT AND VALIDATION OF UV SPECTROSCOPIC METHODS FOR SIMULTANEOUS ESTIMATION OF PARACETAMOL AND ZALTOPROFEN IN BULK AND TABLET FORMULATION

Two methods for simultaneous estimation of Pracetamol and Zaltoprofen in combined tablet dosage form have been developed. The first UV spectrophotometric method was a determination using the simultaneous equation method at 245 nm and 227 nm. The second UV spectrophotometric method is the Q – analysis (absorption ratio) method, which involves the formation of absorbance equation at 237.5 nm (isob...

R.V. Kalamkar *, S. J. Wadher, S. S. Gagare and A. S. Jain

Shri D.D. Vispute College of Pharmacy & Research Center, Gut No. 104, Devad- Vichumbe, Near New Panvel, Panvel – 410206, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).717-21

717-721

2225

1039

28.

EVALUATION OF ANTIMICROBIAL ACTIVITY OF ASAFOETIDA

This study was carried out with the objective of the antibacterial and antifungal activity of chloroform, ethyl acetate, ethanol, methanol and aqueous extracts of Asafoetida. Antibacterial activity was carried out against Bacillus subtilis, Staphylococcus aureus, Klebsiella pneumonia, Escherichia coli and the antifungal activity was evaluated against Aspergillus niger, Candida albicans. The testin...

S. D. Patil*, S. Shinde, P. Kandpile and A. S. Jain

Shri. D. D. Vispute College of Pharmacy and Research center, New Panvel, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).722-27

722-727

3167

850

29.

IDENTIFICATION OF ANTI HYPERLIPIDEMIC ACTIVITY OF CERIUM OXIDE NANO PARTICLES IN RAT MODEL

Cerium oxide is an oxide of the rare earth metal which is widely used for several disorders. However, there are no complete toxicity studies done on it. The purpose of present study is to evaluate acute and Anti-hyper lipidemic activity of cerium oxide nano particles on Wistar albino rats. In this study, Cerium oxide was administered to six rats in different groups in different concentrations (100...

R. Narasimha Naik *, S. Tirupati Rao , D. Durga Rao , K. Ramalingeswara Rao and T. Mohan Rao

Department of Pharmacology, Vagdevi College of Pharmacy, Gurazala - 522415, Andhra Pradesh, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).728-32

728-732

1357

490

30.

ANTIDIABETIC EFFECT OF THE SAPONIN-RICH FRACTION OF THE EXTRACT OF TAMARINDUS INDICA L. ON EXPERIMENTAL HYPERGLYCAEMIA

It is estimated that more than 170 million people are suffering from diabetes globally and this number is expected to double by 2030, and the greatest increase in prevalence is, however, expected to occur in Asia and Africa. Diabetes is the most common endocrine disease and its prevalence is reaching epidemic proportion worldwide. Tamarindus indica is a slow growing tree that is resistant to stron...

M. Yerima *

Department of Pharmacology and Toxicology Usmanu Danfodiyo University, Sokoto Nigeria

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).733-38

733-738

1425

789

31.

PREPARATION AND EVALUATION OF ISONIAZIDE NANO-CONJUGATES FOR IMPROVING THE THERAPEUTIC EFFICIENCY

Raise in the multidrug resistance gave challenge to the treatment of tuberculosis with first line medication due to less response. Nanoparticle drug delivery has proven efficiency in improving the therapeutic efficacy of many drugs. Reduction of dosing frequency was achieved by applying drug delivery using Nano medicine and Green Nanotechnology. The present study aimed in the production of such dr...

D. Sarvamangala *, P. Nagasejitha. , S. Phrabu Seenivasan , L. Srinivas and U.S.N. Murthy

Department of Biotechnology, GIT, GITAM University, Visakhapatnam, Andhrapradesh, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).739-45

739-745

1460

1171

32.

APPLICATION OF DESIGN OF EXPERIMENTS FOR OPTIMIZATION OF RANEY NICKEL MEDIATED BORROWING HYDROGEN REACTION

An efficient, cost effective use of Raney nickel (R-Ni) a widely used industrial catalyst for N-Alkylation using alcohols is highlighted here. The work describes the scope and capability of R-Ni in borrowing hydrogen reactions for Aniline and Benzyl alcohol. The reaction optimization is described using two techniques, Conventional and Design of experiment. The use of DOE for reaction optimization ...

Astha Mehta , A. Thaker , V. Londhe and Santosh R. Nandan *

Ambernath Organics Pvt ltd, 307/314, Creative Industries Premises, Road No.2, Sunder Nagar, Kalina, Mumbai-400098, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).746-51

746-751

1732

787

33.

SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF N-ARYLQUINOXALIN-2-AMINES BEARING BENZIMIDAZOLE DERIVATIVES

In the present study reports synthesis and development of 3-Chloro – N - ((5-chloro-1-tosyl-1H-benzo [d] imidazol – 2 - yl) methyl) - N arylquinoxalin-2-amines (5a-e) from 3-chloro-N-p-tolyl quinoxalin -2-amine (3) condensed with proporgyl bromide followed by adding 4-chloro-N1-tosylbenzene-1,2-diamine,by adopting simple procedure. All titled compounds were screened for their anti bacterial ac...

G. Brahmeshwari *, P. Bhaskar and G. Kumaraswamy

Department of Chemistry, Kakatiya University, Warangal-506 009 (TS) - India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).752-56

752-756.

1291

493

34.

ANTIMICROBIAL ACTIVITY OF AMYCOLATOPSIS ORIENTALIS JAR10 FROM AGRICULTURAL FIELD

Actinomycetes are versatile and prolific source of microbial natural products with great advantage in medicine and agriculture.  Recently there is growing interest in exploring biological active compounds from rare actinomycetes. Usually rare actinomycetes are regarded as strains of actinomycetes whose isolation frequency by conventional methods is much lower than that of Streptomycetes strains. ...

Ritika Chauhan and Jayanthi Abraham*

Microbial Biotechnology Laboratory, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).757-61

757-61

1895

1775

35.

COLUMN CHROMATOGRAPHIC SEPARATION OF BIOACTIVE COMPOUNDS FROM TAGETES ERECTA LINN.

Traditional medicines in many developing countries rely on the plant phytochemicals as a source of drug in curing many diseases. Tagetes erecta Linn. is an ornamental plant containing valuable therapeutic phytochemicals. In the current investigation, ethanol extraction of the dried flower sample was subjected to column chromatographic separation. Around 185 fractions were separated and recorded wi...

R. Devika* and Justine Koilpillai

Department of Biotechnology, Aarupadai Veedu Institute of Technology, Paiyanoor, Tamil Nadu, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).762-66

762-766

2119

903

36.

ROLE OF PROBIOTIC LACTOBACILLUS SPOROGENES IN THE TREATMENT OF ACUTE DIARRHOEA IN CHILDREN

Objective: To investigate the effectiveness of Lactobacillus sporogenes in the treatment of acute diarrhoea in paediatric population. Methods: In a prospective randomized open label comparative study, 62 children (1 month– 6 years) admitted to the Medical College Hospital for the treatment of acute diarrhoea, were included. The patients were randomised into two groups, control group (n =31) rece...

A. K. Manyal and V. D. Phadke*

Professor and Head, Department of Paediatrics, K. J. Somaiya Medical College and Hospital Everard Nagar, Eastern Express Highway, Sion (East), Mumbai 400022, MH, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).767-71

767-771

1944

616

37.

COMPARATIVE ANATOMICAL AND HISTOCHEMICAL STUDIES OF EUPHORBIA HIRTA L. AND EUPHORBIA THYMIFOLIA L. (STEM)

Dugdhika is one of the important raw drug used in Ayurveda. E. thymifolia is used as the genuine source plant of drug Dugdhika, it posses properties like, used for skin disorders, sexual disorders, effective drug for asthma., diarrhoea, dysentery. The present study deals with the comparative study of morphological, anatomical, histochemical characters of E. hirta and E. thymifolia. Two plants show...

K. Sereena* and T. A. Shahida

Department of Botany, MES Asmabi College, P. Vemballur, Thrissur (Dt), Kerala, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).772-77

772-777

2200

614

38.

IN-VITRO CYTOTOXIC ACTIVITY OF SQUID AND CUTTLEFISH BONE EXTRACT ON HEP G2 CELL LINE

The present study was carried out to assess the anticancer activity of methanol extracts of internal bone of L.duvauceli and S. pharaonis for cell viability and toxicity on HepG2 liver cancer cells. The bone extracts had significant cytotoxicity on HepG2 cell in different concentrations (100,500,1000 µg/ml).  Methanol fraction of squid bone powder showed cell death at a higher concentration of 1...

Jemma Hermelin Jesy Diaz*, R.D. Thilag and V. Sivakumar

Assistant Professor St. Mary’s College (Autonomous) Thoothukudi, Tamil Nadu, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).778-82

778-782

1985

1258

39.

A GREENER CHEMISTRY APPROACH FOR SYNTHESIS OF 4-(4-HYDROXYPHENYL)-6-METHYL-2-OXO-1,2,3,4 TETRAHYDROPYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER

The objective of present research work is to provide green technique for synthesis of 4-(4-Hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester. Pyrimidine derivatives are well known in the pharmaceutical industry and exhibit to possess a broad spectrum of biological activities. Highly efficient and simple methods complying with principle of Green chemistry have...

D. Jagwani* and P. Joshi

Medi-Caps Group of Institutions, Pigdamber, Rau, Indore- 453331, Madhya Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).783-90

783-790

1417

1809

40.

FORMULATION AND PROCESS VALIDATION OF DICLOFENAC SODIUM AND PARACETAMOL COMBINATION TABLET

A properly designed system will provide a high degree of assurance that every step, process, and change has been properly evaluated before its implementation. Validation is an important step carried out in order to control the entire process, and the process adapted to produce itself must assure that process will consistently produce the expected results and maintain the desired quality of the fin...

Peeyush Yadav*

HSN International, Haridwar, Uttarakhand, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).791-97

791-797

4516

1350

41.

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING METHOD FOR SIMULTANEOUS ESTIMATION OF FEBUXOSTAT AND DICLOFENAC POTASSIUM IN BULK AND TABLET DOSAGE FORM USING RP-HPLC

A novel method for the simultaneous estimation of Febuxostat and Diclofenac Potassium in combine dosage form was developed and validated by reverse phase high performance liquid chromatography. The determination was performed on an Inertsil C18 column (100mm x 4.6 mm ID, 5µm particle size) and the mobile phase consisting a mixture of 0.01M Ammonium di-hydrogen phosphate buffer (pH adjusted to 5 w...

Uttam Prasad Panigrahy * and A. Sunil Kumar Reddy

Department of Pharmaceutical Analysis and Quality Assurance, Malla Reddy College of Pharmacy, Maisammaguda, Dullapally, Secunderabad, 500014, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).798-07

798-807

2374

997

42.

FORMULATION AND EVALUATION OF IMMEDIATE RELEASE TABLET OF VALSARTAN

The immediate release tablet of antihypertensive drug Valsartan were prepared and evaluated to increase solubility and bioavailability of low soluble drug. The tablets were prepared by direct compression method using Surfactants such as Poloxamer 188, Sodium stearate, Sodium Lauryl Sulfate and Superdisintegrant such as Cross carmellose sodium were used in tablet formulation. The formulation were e...

Rohit S. Kulkarni*and Dr. Amulyaratna L. Behera

Vishal Institute of Pharmaceutical Education and Research, Ale Tal- Junnar, Dist-Pune, Maharashtra, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).808-15

808-815

4880

1493

43.

DERMATOLOGICAL ADVERSE DRUG REACTIONS IN TERTIARY CARE HOSPITAL

Adverse drug reactions are undesirable effects of drugs beyond its anticipated therapeutic uses occurring commonly in clinical practice. Although many of these ADRs are mild and disappear when the suspected drug is stopped or dose is reduced, some are more serious and last longer. Many studies have been published regarding hospital admission due to ADRs and it has been estimated that 2.9% to 5.6% ...

Neha Tabassum, Mohd Ilyas , Syedazizullah Ghori , Ashok Reddy and Mohd Mohiuddin 2

Deccan School of Pharmacy, Hyderabad-500 058, Andhra Pradesh, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).816-24

816-824

1808

605

44.

PHARMACOGNOSTIC AND PHYTOCHEMICAL INVESTIGATION ON STEM BARK OF CHLOROXYLON SWIETENIA DC. AN ETHNOMEDICINALLY IMPORTANT MEDICINAL TREE

Chloroxylon swietenia DC. belongs to the family Rutaceae / Meliaceae / Chloroxylaceae, is a medicinal and aromatic tree of dry deciduous forests. It is popularly known as Yellow wood, East Indian satin wood and Ceylon satin wood. The stem bark is credited for its effectiveness in the treatment of common cough and cold, it is also used as an astringent. Its pharmacognostic data for authentication o...

Sharanabasappa Melmari * and M. Jayaraj

P. G. Department of Botany, Karnatak University, Dharwad, Karnataka, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).825-29

825-829

1765

550

45.

UV-VISIBLE SPECTRAL ANALYSIS OF BORIC ACID IN DIFFERENT SOLVENTS: A CASE STUDY

Boric acid is one of the widely used inorganic compound in pharmaceutical industry. We find its utilization as an antiseptic, in eye wash preparations, as an insecticidal, as a buffering agent etc.  In this present work, a comparative study of the UV-Vis spectras of the boric acid solution in different solvents have been done. A variety of solvents like water, ethanol, methanol, glacial acetic ac...

Sarbjeet Singh Gujral

Maharaja Surajmal Institute of Pharmacy, C-4, Janakpuri, New Delhi, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).830-34

830-834

4232

1781

46.

SOLUBILITY ENHANCEMENT OF MELOXICAM BY LIQUISOLID TECHNIQUE AND ITS CHARACTERIZATION

Solubility is the important parameter to design a dosage form; it is very difficult to formulate an insoluble drug in to final formulation. In This present study deals with the enhancement of solubility of poorly water soluble drug Meloxicam.: The liquisolid system is a novel technique for solubility enhancement and dissolution improvement of low soluble drugs. Liquisolid technique (powdered solut...

Janakidevi Sirisolla

A.U. College of Pharmaceutical Sciences, Andhra University, Visakhapatnam. Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).835-40

835-840

2436

1152

47.

ANTIMICROBIAL ACTIVITY OF BURSERA PENICILLATA LEAF EXTRACTS ON HUMAN INFECTIOUS PATHOGENS

The purpose of this study was to evaluate antimicrobial activity of Bursera penicillata leaf extract against human infected bacteria. Antimicrobial activity of Petrolium ether, Methanolic and Aqueous extracts from leaves of Bursera penicillata were tested against pathogenic bacteria Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae, Staphylococcus saprophyticus, Ente...

T. Ashok *, N. Madhuri, G.L.N Raju and M. Rani

Department of Microbiology, Ventura Institute of Biosciences1, Moosaram Bagh, Hyderabad, Telangana, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).841-44

841-844

2068

773

48.

SINGLE-STEP PURIFICATION OF UREASE FROM CANAVALIA GLADIATA SEEDS

The urease (E.C.3.5.1.5) catalyzes the hydrolysis of urea to ammonia and is commonly used in clinical laboratories for the estimation of urea in biological fluids. The urease enzyme of sword bean (Canavalia gladiata) has been purified in single-step by affinity chromatography using epoxy activated agarose containing urea as the affinity ligand. The yield of the purified enzyme was about 83% with s...

ASM Saem, Md. Tanvir Hossain , DHN Chandan , M. Abdul Mottaleb and M. Taufiq Alam

Assistant Professor, Department of Applied Chemistry and Chemical Engineering, Noakhali Science & Technology University, Noakhali-3814, Bangladesh.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).845-49

845-849

2287

950

49.

SYNTHESIS OF THIAZOLIDINONE AND AZETIDINONE DERIVATIVES OF BENZOXAZOLINONE AS ANTIMICROBIAL AGENTS

The present investigation is concerned with synthesis of new substituted benzoxazolinone derivatives (1-18) with the objective of discovering novel and potent antimicrobial agents. The structure of all the synthesized compounds were elucidated by elemental (C, H, N) and spectral (IR, 1HNMR and mass) analysis. The purity of the synthesized compounds was checked by thin layer chromatography (TLC). T...

I. Singh * and A. Kumar

Department of Chemistry Janta Vedic College Baraut (Baghpat) U.P, India 250611

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).850-56

850-856

1542

637

50.

A PEDICULICIDAL ACTIVITY OF CLOVE OIL

The humans head lice are a nuisance for millions of people worldwide with high prevalence in children. Head lice have been treated by methods that include the physical removal of lice, various domestic treatments and conventional insecticides. None of these methods render complete protection and there is clear evidence for the evolution of resistance and cross-resistance to conventional insecticid...

Trupti D. Dhumal and J. S. Waghmare*

Department of Oils, Oleo chemicals and Surfactants Technology, Institute of Chemical Technology, Mumbai-400019, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).857-65

857-865

2338

854

51.

FABRICATION AND CHARACTERIZATION OF MICROEMULSION BASED ORAL SOLID DOSAGE FORM OF GLIMEPIRIDE

The aim of this investigation was to develop a solid microemulsion of Glimepiride for enhancing its solubility, and its dissolution rate. For this purpose, solubility of Glimepiride was determined in various vehicles. Oil, Surfactant and Cosurfactant were selected based on the solubility. Pseudo-ternary phase diagrams were constructed to identify the microemulsion existing zone. The optimized micr...

Sushant Mishra* and Gouri Dixit

Department of Pharmaceutics, Priyadarshini J.L College of Pharmacy, Electronic Zone, Hingna Road, M.I.D.C., Nagpur – 440016, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).866-74

866-874

2198

1372

52.

IN VIVO AND IN VITRO DETERMINATION OF TOTAL PHENOLS, ASCORBIC ACID CONTENT AND ANTIOXIDANT ACTIVITY IN PLUCHEA LANCEOLATA OLIVER & HIERN.

The present investigation deals with the determination of in vitro antioxidant activity as well as the phenols and ascorbic acid content in in vivo (leaf, stem, root) and in vitro (unorganised static callus cultures) plant parts of Pluchea lanceolata. Unorganised static callus cultures (eighteen months old) were grown on MS medium supplemented with NAA (1.0 mg/l) and BAP (0.5 mg/l) using leaf expl...

Deepika Arya *, Vidya Patni Preeta Nair and Radha D. Kale

Post Doctoral Fellow Department of Biotechnology, Mount Carmel College, Bangalore-560052, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).875-79

875-879

1538

797

53.

PHYTOCHEMICAL STUDIES ON CARICA PAPAYA LEAF JUICE

Whole plant parts, fruits, roots, bark, peel, seeds and pulp of Carica papaya are known to have medicinal properties. It has been used for treatment of numerous diseases like warts, corns, sinuses, eczema, cutaneous tubercles, blood pressure, dyspepsia, constipation, amenorrhoea, general debility, expel thread worms and stimulate reproductive organs. Ayurvedic literature reveals that papaya leaf e...

S. Akhila * and N. G. Vijayalakshmi

Department of Pharmaceutical Sciences, Regional Institute of medical Sciences and research, Mahatma Gandhi University, Rubber Board P.O, Kottyam. Kerala, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).880-83

880-883

5737

3154

54.

DEVELOPMENT AND VALIDATION OF A HPLC-UV METHOD FOR SIMULTANEOUS DETERMINATION OF CEFIXIME AND OFLOXACIN IN TABLET FORMULATION

A simple, rapid, and sensitive high-performance liquid chromatographic method with UV detection has been developed and validated according to the ICH guidelines for the quantization of Cefixime (CFXM) and Ofloxacin (OFLO) in tablet preparation. Chromatographic separation was carried out in a Agilent Zorbax Eclipse XDB-C18 column (150 mm × 4.6 mm; 5 μm particle size) of Agilent Technologies with ...

Sarbojit Kundu*, Tapas Majumder, Prasanta Kumar Barat and Subrata Kumar Ray

Central Drugs Laboratory, (Govt. of India), 3, Kyd Street, Kolkata-700 016, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).884-89

884-889

2315

598

55.

EVALUATION OF THE ANTIDEPRESSANT EFFECTS OF BACOPA MONIERI IN MICE

Bacopamonnieri L. Pennell (family: Sclorphulariaceae) is a reputed drug of Ayurveda. The present study was undertaken to investigate the antidepressant activity of alcoholic extract of B. monnieri was studied at doses of 40 mg / kg and 80 mg / kg against TST and FST mice model of depression. Dose dependent reductions in immobility time were observed in TST and FST mice model of depression. The res...

Ujwala Wasnik *, Vijender Singh and Mohammad Ali

Mouda road, Shitalwadi colony T-Point Ramtek, Thasil Ramtek, Dist Nagpur, Pin code:441106 India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).890-94

890-894

1656

867

56.

ANTI-ULCER ACTIVITY OF ETHANOL EXTRACT OF PARKIA SPECIOSA AGAINST INDOMETHACIN INDUCED PEPTIC ULCER IN ALBINO RATS

This study was performed to determine the anti-ulcer effects of ethanol extract of Parkia speciosa on Indomethacin induced peptic ulcer in Albino rats. Rats of female sex weighing between 150 g - 200 g were used. Rats were divided into six groups with six rats in each group. Omeprazole (20 mg/kg) were used as a standard drug for this study. Parkia speciosa extract were given in three different dos...

M. Santha Maria*, Surya Devarakonda , Ajay Kumar TV and N. Balakrishnan

School of Biomedicine, Asia Metropolitan University, G-8, Jalan Kemacahaya 11, Batu 9, 43200 Cheras, Selangor, Malaysia

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).895-902

895-902

1755

959

57.

EFFECT OF PLACEBO ON DEPRESSION

Depression is a well defined mood disorder which is characterized by state of disposition of mind and dislike or antipathy to activity that can affect an individual’s thoughts, demeanor, sense of emotional touch and physical well- being. Depressed people may feel mournful, troubled, uneasy in mind, meaningless, helpless and unworthy, experiencing as if having committed an offence. They are easil...

Girija Shankar Shukla * and Pramod Kumar Rai

Faculty of Health Sciences, Sam Higginbottom Institute of Agriculture, Technology & Sciences-Deemed University, Allahabad, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).903-13

903-913

1464

447

58.

STUCTURAL AND SPECTROSCOPIC STUDY OF Cu(II) – TAURINE –HEXAMINE TERNARY COMPLEX: DETERMINATION OF THE STABILITY CONSTANTS IN METHANOL – WATER MIXTURES

Stoichiometry and apparent stability constant (KC) of the complex formed between Cu(II), hexamine and taurine were determined in water and methanol-water mixtures (% methanol w/w: 3.11; 6.15; 10.4; 15.2; 19.9 and 25.3) by UV–vis spectroscopy at 25o C and constant ionic strength (0.05 M, sodium chloride). Stoichiometry of the ternary complex (1:1: 2, metal: hexamine: taurine) is not modified with...

M. K. Sharaf El Din and M. E. K. Wahba*

Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).914-23

914-923

1594

605

59.

INDUCTION OF CALLOGENESIS AND SHOOTING IN ASTERACANTHA LONGIFOLIA(L.) NEES –A MEDICINAL HERB

This study is concerned to develop a rapid system for regenerating shoots and callus from mature shoot tip explants of Asteracantha longifolia (L.) Nees, a medicinally important annual herb (family acanthaceae). Effective shoot and callus   regeneration was observed by using several concentrations of cytokinins and auxins with MS medium.  Shoot tips responded better for callusing almost in all ...

Ashiq Hussain Khanday

Department of Botany Sant Gadge Baba Amravati University, Amravati (M.S) - 444602, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).924-27

924-927

1483

696

60.

FORMULATION AND EVALUATION OF STAVUDINEAS MUCOADHESIVE VAGINAL TABLETS

Mucoadhesive drug delivery system has occupied an important place in the field of pharmaceutical research. Mucoadhesive tablets prolong the residence time of the drug at the site of application and provide extended therapeutic effect. Mucoadhesive tablets have been prepared for various sites thus offering localization as swell as systemic control of drug release. The present review focuses on conc...

P. Preetha*, A. Srinivasa Rao and B. BanutejaNaik

Department of Pharmaceutics, Bhaskar Pharmacy College, Hyderabad, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).928-34

928-934

1586

616